| The pregnane X receptor: a promiscuous xenobiotic receptor that has diverged during evolution SA Jones, LB Moore, JL Shenk, GB Wisely, GA Hamilton, DD McKee, ... Molecular endocrinology 14 (1), 27-39, 2000 | 871 | 2000 |
| Discovery of I-BRD9, a selective cell active chemical probe for bromodomain containing protein 9 inhibition NH Theodoulou, P Bamborough, AJ Bannister, I Becher, RA Bit, KH Che, ... Journal of medicinal chemistry 59 (4), 1425-1439, 2016 | 220 | 2016 |
| A public-private partnership to unlock the untargeted kinome S Knapp, P Arruda, J Blagg, S Burley, DH Drewry, A Edwards, D Fabbro, ... Nature chemical biology 9 (1), 3-6, 2013 | 173 | 2013 |
| Circadian clock component REV-ERBα controls homeostatic regulation of pulmonary inflammation M Pariollaud, JE Gibbs, TW Hopwood, S Brown, N Begley, R Vonslow, ... The Journal of clinical investigation 128 (6), 2281-2296, 2018 | 159 | 2018 |
| Identification of peroxisome proliferator-activated receptor ligands from a biased chemical library PJ Brown, TA Smith-Oliver, PS Charifson, NCO Tomkinson, AM Fivush, ... Chemistry & biology 4 (12), 909-918, 1997 | 147 | 1997 |
| Molecular basis of fatty acid selectivity in the zDHHC family of S-acyltransferases revealed by click chemistry J Greaves, KR Munro, SC Davidson, M Riviere, J Wojno, TK Smith, ... Proceedings of the National Academy of Sciences 114 (8), E1365-E1374, 2017 | 137 | 2017 |
| Alkene syn dihydroxylation with malonoyl peroxides JC Griffith, KM Jones, S Picon, MJ Rawling, BM Kariuki, M Campbell, ... Journal of the American Chemical Society 132 (41), 14409-14411, 2010 | 131 | 2010 |
| Microwave‐assisted synthesis of pyrimidine libraries MC Bagley, DD Hughes, MC Lubinu, EA Merritt, PH Taylor, ... QSAR & Combinatorial Science 23 (10), 859-867, 2004 | 111 | 2004 |
| Secondary and primary amine catalysts for iminium catalysis JB Brazier, NCO Tomkinson Asymmetric Organocatalysis, 281-347, 2009 | 110 | 2009 |
| A general method for the α-acyloxylation of carbonyl compounds CS Beshara, A Hall, RL Jenkins, KL Jones, TC Jones, NM Killeen, ... Organic letters 7 (25), 5729-5732, 2005 | 109 | 2005 |
| Optimized chemical probes for REV-ERBα RP Trump, S Bresciani, AWJ Cooper, JP Tellam, J Wojno, J Blaikley, ... Journal of medicinal chemistry 56 (11), 4729-4737, 2013 | 95 | 2013 |
| Solution phase, solid state, and theoretical investigations on the MacMillan imidazolidinone JB Brazier, G Evans, TJK Gibbs, SJ Coles, MB Hursthouse, JA Platts, ... Organic Letters 11 (1), 133-136, 2009 | 91 | 2009 |
| Differential activity of rosiglitazone enantiomers at PPARγ DJ Parks, NCO Tomkinson, MS Villeneuve, SG Blanchard, TM Willson Bioorganic & medicinal chemistry letters 8 (24), 3657-3658, 1998 | 87 | 1998 |
| Clinical progress and pharmacology of small molecule bromodomain inhibitors NH Theodoulou, NCO Tomkinson, RK Prinjha, PG Humphreys Current opinion in chemical biology 33, 58-66, 2016 | 83 | 2016 |
| Metal-free syn-dioxygenation of alkenes MJ Rawling, NCO Tomkinson Organic & Biomolecular Chemistry 11 (9), 1434-1440, 2013 | 75 | 2013 |
| Copper-catalyzed coupling of hydroxylamines with aryl iodides KL Jones, A Porzelle, A Hall, MD Woodrow, NCO Tomkinson Organic letters 10 (5), 797-800, 2008 | 73 | 2008 |
| Palladium-catalyzed coupling of hydroxylamines with aryl bromides, chlorides, and iodides A Porzelle, MD Woodrow, NCO Tomkinson Organic Letters 11 (1), 233-236, 2009 | 72 | 2009 |
| Fam49/CYRI interacts with Rac1 and locally suppresses protrusions L Fort, JM Batista, PA Thomason, HJ Spence, JA Whitelaw, L Tweedy, ... Nature cell biology 20 (10), 1159-1171, 2018 | 70 | 2018 |
| Metal-free dihydroxylation of alkenes using cyclobutane malonoyl peroxide KM Jones, NCO Tomkinson The Journal of Organic Chemistry 77 (2), 921-928, 2012 | 68 | 2012 |
| The α-effect in iminium ion catalysis JL Cavill, RL Elliott, G Evans, IL Jones, JA Platts, AM Ruda, ... Tetrahedron 62 (2-3), 410-421, 2006 | 65 | 2006 |
Tim WillsonProfessor, UNC Eshelman School of Pharmacy, UNC Chapel HillEmail verificata su unc.edu
