Structural biology of factor VIIa/tissue factor initiated coagulation K Vadivel, SP Bajaj Frontiers in bioscience: a journal and virtual library 17, 2476, 2012 | 71 | 2012 |
Drug-induced modulation of gp130 signalling prevents articular cartilage degeneration and promotes repair R Shkhyan, B Van Handel, J Bogdanov, S Lee, Y Yu, M Scheinberg, ... Annals of the rheumatic diseases 77 (5), 760-769, 2018 | 55 | 2018 |
Engineering Kunitz Domain 1 (KD1) of Human Tissue Factor Pathway Inhibitor-2 to Selectively Inhibit Fibrinolysis: PROPERTIES OF KD1-L17R VARIANT*♦ MS Bajaj, GI Ogueli, Y Kumar, K Vadivel, G Lawson, S Shanker, ... Journal of biological chemistry 286 (6), 4329-4340, 2011 | 50 | 2011 |
Structural and functional studies of γ-carboxyglutamic acid domains of factor VIIa and activated Protein C: role of magnesium at physiological calcium K Vadivel, S Agah, AS Messer, D Cascio, MS Bajaj, S Krishnaswamy, ... Journal of molecular biology 425 (11), 1961-1981, 2013 | 37 | 2013 |
Suppression of tau propagation using an inhibitor that targets the DK-switch of nSMase2 T Bilousova, C Elias, E Miyoshi, MP Alam, C Zhu, J Campagna, K Vadivel, ... Biochemical and biophysical research communications 499 (4), 751-757, 2018 | 31 | 2018 |
The heterodimeric structure of heterogeneous nuclear ribonucleoprotein C1/C2 dictates 1, 25-dihydroxyvitamin D-directed transcriptional events in osteoblasts TS Lisse, K Vadivel, SP Bajaj, R Zhou, RF Chun, M Hewison, JS Adams Bone research 2 (1), 1-11, 2014 | 29 | 2014 |
Platelets contain tissue factor pathway inhibitor-2 derived from megakaryocytes and inhibits fibrinolysis K Vadivel, SM Ponnuraj, Y Kumar, AK Zaiss, MW Bunce, RM Camire, ... Journal of Biological Chemistry 289 (45), 31647-31661, 2014 | 28 | 2014 |
Dual neutral sphingomyelinase-2/acetylcholinesterase inhibitors for the treatment of Alzheimer’s disease T Bilousova, BJ Simmons, RR Knapp, CJ Elias, J Campagna, M Melnik, ... ACS chemical biology 15 (6), 1671-1684, 2020 | 23 | 2020 |
Protein structure prediction using mutually orthogonal Latin squares and a genetic algorithm J Arunachalam, V Kanagasabai, N Gautham Biochemical and Biophysical Research Communications 342 (2), 424-433, 2006 | 22 | 2006 |
A small molecule mimetic of the humanin peptide as a candidate for modulating NMDA-induced neurotoxicity MP Alam, T Bilousova, P Spilman, K Vadivel, D Bai, CJ Elias, D Evseenko, ... ACS Chemical Neuroscience 9 (3), 462-468, 2017 | 18 | 2017 |
Sodium‐site in serine protease domain of human coagulation factor IXa: evidence from the crystal structure and molecular dynamics simulations study K Vadivel, HA Schreuder, A Liesum, AE Schmidt, G Goldsmith, SP Bajaj Journal of Thrombosis and Haemostasis 17 (4), 574-584, 2019 | 16 | 2019 |
The first intrinsic tenase complex inhibitor with serine protease structure offers a new perspective in anticoagulant therapy Z Latinović, A Leonardi, L Kovačič, CY Koh, J Šribar, AT Bakija, ... Thrombosis and Haemostasis 118 (10), 1713-1728, 2018 | 14 | 2018 |
Exploring the conformational space of protein loops using a mean field technique with MOLS sampling V Kanagasabai, J Arunachalam, P Arun Prasad, N Gautham Proteins: Structure, Function, and Bioinformatics 67 (4), 908-921, 2007 | 12 | 2007 |
Inhibition of a signaling modality within the gp130 receptor enhances tissue regeneration and mitigates osteoarthritis R Shkhyan, C Flynn, E Lamoure, A Sarkar, B Van Handel, J Li, J York, ... Science translational medicine 15 (688), eabq2395, 2023 | 8 | 2023 |
Structure and function of vitamin K-dependent coagulation and anticoagulation proteins K Vadivel, AE Schmidt, VJ Marder, S Krishnaswamy, SP Bajaj Hemostasis and Thrombosis: basic principles and clinical practice, 208-32, 2012 | 8 | 2012 |
Conformational sampling in structure prediction and refinement with atomistic and coarse-grained models M Feig, SM Gopal, K Vadivel, A Stumpff-Kane Multiscale approaches to protein modeling: Structure prediction, dynamics …, 2011 | 7 | 2011 |
Evaluation of an Allosteric BACE Inhibitor Peptide to identify mimetics that can interact with the loop F region of the enzyme and prevent APP cleavage J Campagna, K Vadivel, B Jagodzinska, M Jun, T Bilousova, P Spilman, ... Journal of molecular biology 430 (11), 1566-1576, 2018 | 6 | 2018 |
Interaction of factor V B-domain acidic region with its basic region and with TFPI/TFPI2: Structural insights from molecular modeling studies K Vadivel, Y Kumar, MW Bunce, RM Camire, MS Bajaj, SP Bajaj International biology review 1 (1), 2017 | 6 | 2017 |
Exploring conformational space using a mean field technique with MOLS sampling PA Prasad, V Kanagasabai, J Arunachalam, N Gautham Journal of biosciences 32, 909-920, 2007 | 6 | 2007 |
Quantifying vitamin K-dependent holoprotein compaction caused by differential γ-carboxylation using high-pressure size exclusion chromatography NC Vanderslice, AS Messer, K Vadivel, SP Bajaj, M Phillips, M Fatemi, ... Analytical biochemistry 479, 6-14, 2015 | 4 | 2015 |