Dynamic modeling of imatinib-treated chronic myeloid leukemia: functional insights and clinical implications I Roeder, M Horn, I Glauche, A Hochhaus, MC Mueller, M Loeffler Nature medicine 12 (10), 1181-1184, 2006 | 348 | 2006 |
Tissue stem cells: definition, plasticity, heterogeneity, self-organization and models–a conceptual approach M Loeffler, I Roeder Cells Tissues Organs 171 (1), 8-26, 2002 | 262 | 2002 |
A novel dynamic model of hematopoietic stem cell organization based on the concept of within-tissue plasticity I Roeder, M Loeffler Experimental hematology 30 (8), 853-861, 2002 | 194 | 2002 |
Towards an understanding of lineage specification in hematopoietic stem cells: a mathematical model for the interaction of transcription factors GATA-1 and PU. 1 I Roeder, I Glauche Journal of theoretical biology 241 (4), 852-865, 2006 | 158 | 2006 |
High-speed panoramic light-sheet microscopy reveals global endodermal cell dynamics B Schmid, G Shah, N Scherf, M Weber, K Thierbach, CP Campos, ... Nature communications 4 (1), 1-10, 2013 | 152 | 2013 |
Mice in an enriched environment learn more flexibly because of adult hippocampal neurogenesis A Garthe, I Roeder, G Kempermann Hippocampus 26 (2), 261-271, 2016 | 139 | 2016 |
Nanog variability and pluripotency regulation of embryonic stem cells-insights from a mathematical model analysis I Glauche, M Herberg, I Roeder PloS one 5 (6), e11238, 2010 | 113 | 2010 |
Stem cell proliferation and quiescence—two sides of the same coin I Glauche, K Moore, L Thielecke, K Horn, M Loeffler, I Roeder PLoS Comput Biol 5 (7), e1000447, 2009 | 98 | 2009 |
Lineage specification of hematopoietic stem cells: mathematical modeling and biological implications I Glauche, M Cross, M Loeffler, I Roeder Stem cells 25 (7), 1791-1799, 2007 | 89 | 2007 |
Competitive clonal hematopoiesis in mouse chimeras explained by a stochastic model of stem cell organization I Roeder, LM Kamminga, K Braesel, B Dontje, G de Haan, M Loeffler Blood 105 (2), 609-616, 2005 | 84 | 2005 |
The bulk of the hematopoietic stem cell population is dispensable for murine steady-state and stress hematopoiesis KB Schoedel, MNF Morcos, T Zerjatke, I Roeder, T Grinenko, ... Blood 128 (19), 2285-2296, 2016 | 71 | 2016 |
Model-based decision rules reduce the risk of molecular relapse after cessation of tyrosine kinase inhibitor therapy in chronic myeloid leukemia M Horn, I Glauche, MC Müller, R Hehlmann, A Hochhaus, M Loeffler, ... Blood, The Journal of the American Society of Hematology 121 (2), 378-384, 2013 | 68 | 2013 |
Characterization and quantification of clonal heterogeneity among hematopoietic stem cells: a model-based approach I Roeder, K Horn, HB Sieburg, R Cho, C Muller-Sieburg, M Loeffler Blood, The Journal of the American Society of Hematology 112 (13), 4874-4883, 2008 | 56 | 2008 |
Insertional mutagenesis and clonal dominance: biological and statistical considerations B Fehse, I Roeder Gene therapy 15 (2), 143-153, 2008 | 56 | 2008 |
QuickMap: a public tool for large-scale gene therapy vector insertion site mapping and analysis JU Appelt, FA Giordano, M Ecker, I Roeder, N Grund, A Hotz-Wagenblatt, ... Gene therapy 16 (7), 885-893, 2009 | 55 | 2009 |
In vivo time-lapse imaging shows diverse niche engagement by quiescent and naturally activated hematopoietic stem cells NM Rashidi, MK Scott, N Scherf, A Krinner, JS Kalchschmidt, K Gounaris, ... Blood, The Journal of the American Society of Hematology 124 (1), 79-83, 2014 | 53 | 2014 |
Multiplexing clonality: combining RGB marking and genetic barcoding K Cornils, L Thielecke, S Hüser, M Forgber, M Thomaschewski, N Kleist, ... Nucleic acids research 42 (7), e56-e56, 2014 | 53 | 2014 |
Activation of Evi1 inhibits cell cycle progression and differentiation of hematopoietic progenitor cells OS Kustikova, A Schwarzer, M Stahlhut, MH Brugman, T Neumann, ... Leukemia 27 (5), 1127-1138, 2013 | 53 | 2013 |
Asymmetry of stem cell fate and the potential impact of the niche I Roeder, R Lorenz Stem cell reviews 2 (3), 171-180, 2006 | 53 | 2006 |
Conceptual models to understand tissue stem cell organization M Loeffler, I Roeder Current opinion in hematology 11 (2), 81-87, 2004 | 53 | 2004 |