| Crystal structure of the dengue virus RNA-dependent RNA polymerase catalytic domain at 1.85-angstrom resolution TL Yap, T Xu, YL Chen, H Malet, MP Egloff, B Canard, SG Vasudevan, ... Journal of virology 81 (9), 4753-4765, 2007 | 495 | 2007 |
| The flavivirus polymerase as a target for drug discovery H Malet, N Massé, B Selisko, JL Romette, K Alvarez, JC Guillemot, ... Antiviral research 80 (1), 23-35, 2008 | 249 | 2008 |
| α-Synuclein interacts with glucocerebrosidase providing a molecular link between Parkinson and Gaucher diseases TL Yap, JM Gruschus, A Velayati, W Westbroek, E Goldin, N Moaven, ... Journal of biological chemistry 286 (32), 28080-28088, 2011 | 214 | 2011 |
| α-Synuclein shows high affinity interaction with voltage-dependent anion channel, suggesting mechanisms of mitochondrial regulation and toxicity in Parkinson disease TK Rostovtseva, PA Gurnev, O Protchenko, DP Hoogerheide, TL Yap, ... Journal of Biological Chemistry 290 (30), 18467-18477, 2015 | 181 | 2015 |
| Membrane-bound α-synuclein interacts with glucocerebrosidase and inhibits enzyme activity TL Yap, A Velayati, E Sidransky, JC Lee Molecular genetics and metabolism 108 (1), 56-64, 2013 | 124 | 2013 |
| Mutagenesis of the dengue virus type 2 NS5 methyltransferase domain H Kroschewski, SP Lim, RE Butcher, TL Yap, J Lescar, PJ Wright, ... Journal of biological chemistry 283 (28), 19410-19421, 2008 | 91 | 2008 |
| A scintillation proximity assay for dengue virus NS5 2′-O-methyltransferase—kinetic and inhibition analyses SP Lim, D Wen, TL Yap, CK Yan, J Lescar, SG Vasudevan Antiviral research 80 (3), 360-369, 2008 | 66 | 2008 |
| Structural features of membrane-bound glucocerebrosidase and α-synuclein probed by neutron reflectometry and fluorescence spectroscopy TL Yap, Z Jiang, F Heinrich, JM Gruschus, CM Pfefferkorn, M Barros, ... Journal of Biological Chemistry 290 (2), 744-754, 2015 | 60 | 2015 |
| Saposin C protects glucocerebrosidase against α-synuclein inhibition TL Yap, JM Gruschus, A Velayati, E Sidransky, JC Lee Biochemistry 52 (41), 7161-7163, 2013 | 55 | 2013 |
| Residue-specific fluorescent probes of α-synuclein: detection of early events at the N-and C-termini during fibril assembly TL Yap, CM Pfefferkorn, JC Lee Biochemistry 50 (12), 1963-1965, 2011 | 41 | 2011 |
| NMR structure of calmodulin complexed to an N-terminally acetylated α-synuclein peptide JM Gruschus, TL Yap, JC Lee Biophysical Journal 104 (2), 52a, 2013 | 36 | 2013 |
| Alpha-synuclein lipid-dependent membrane binding and translocation through the α-hemolysin channel PA Gurnev, TL Yap, CM Pfefferkorn, TK Rostovtseva, AM Berezhkovskii, ... Biophysical journal 106 (3), 556-565, 2014 | 32 | 2014 |
| Dissociation of glucocerebrosidase dimer in solution by its co-factor, saposin C JM Gruschus, Z Jiang, TL Yap, SA Hill, A Grishaev, G Piszczek, ... Biochemical and biophysical research communications 457 (4), 561-566, 2015 | 28 | 2015 |
| The yin and yang of amyloid: insights from α-synuclein and repeat domain of Pmel17 RP McGlinchey, TL Yap, JC Lee Physical Chemistry Chemical Physics 13 (45), 20066-20075, 2011 | 26 | 2011 |
| A multi-step strategy to obtain crystals of the dengue virus RNA-dependent RNA polymerase that diffract to high resolution TL Yap, YL Chen, T Xu, D Wen, SG Vasudevan, J Lescar Acta Crystallographica Section F: Structural Biology and Crystallization …, 2007 | 24 | 2007 |
| A phase I study of oral belinostat (PXD101) in patients with advanced solid tumors WK Kelly, T Yap, J Lee, U Lassen, E Crowley, A Clarke, T Hawthorne, ... Journal of Clinical Oncology 25 (18_suppl), 14092-14092, 2007 | 15 | 2007 |
| Alpha-Synuclein Blocks VDAC Suggesting Mechanism of Mitochondrial Regulation and Toxicity in Parkinson Disease PA Gurnev, TK Rostovtseva, DP Hoogerheide, O Protchenko, TL Yap, ... Biophysical Journal 108 (2), 607a, 2015 | | 2015 |
| Saposin C Protects Glucocerebrosidase against-Synuclein Inhibition TL Yap, V Arashauthor, S Ellenauthor | | 2015 |
| Molecular Details of α-Synuclein Membrane Association Revealed by Neutron Reflectometry JC Lee, Z Jiang, S Hess, RP McGlinchey, TL Yap, F Heinrich Biophysical Journal 106 (2), 17a, 2014 | | 2014 |
| Parkinson Disease-Associated Protein α-Synuclein Blocks VDAC Providing New Insights into Mitochondrial Toxicity TK Rostovtseva, PA Gurnev, TL Yap, JC Lee, SM Bezrukov Biophysical Journal 106 (2), 590a, 2014 | | 2014 |
