Follow
Brandon Zimmerman
Brandon Zimmerman
Verified email at vrtx.com
Title
Cited by
Cited by
Year
Mechanical Allostery: Evidence for a Force Requirement in the Proteolytic Activation of Notch
W Gordon, B Zimmerman, L He, L Miles, J Huang, K Tiyanont, D McArthur, ...
Developmental Cell 33 (6), 729-736, 2015
3832015
Crystal structure of a full-length human tetraspanin reveals a cholesterol-binding pocket
B Zimmerman, B Kelly, BJ McMillan, TCM Seegar, RO Dror, AC Kruse, ...
Cell 167 (4), 1041-1051. e11, 2016
2702016
Differential β-arrestin–dependent conformational signaling and cellular responses revealed by angiotensin analogs
B Zimmerman, A Beautrait, B Aguila, R Charles, E Escher, A Claing, ...
Science signaling 5 (221), ra33-ra33, 2012
1682012
Structural basis for regulated proteolysis by the α-secretase ADAM10
TCM Seegar, LB Killingsworth, N Saha, PA Meyer, D Patra, B Zimmerman, ...
Cell 171 (7), 1638-1648. e7, 2017
1492017
A new inhibitor of the β-arrestin/AP2 endocytic complex reveals interplay between GPCR internalization and signalling
A Beautrait, JS Paradis, B Zimmerman, J Giubilaro, L Nikolajev, ...
Nature communications 8 (1), 15054, 2017
1422017
c-Src-mediated phosphorylation of AP-2 reveals a general mechanism for receptors internalizing through the clathrin pathway
B Zimmerman, M Simaan, MH Lee, LM Luttrell, SA Laporte
Cellular signalling 21 (1), 103-110, 2009
682009
Inaxaplin for Proteinuric Kidney Disease in Persons with Two APOL1 Variants
O Egbuna, B Zimmerman, G Manos, A Fortier, MC Chirieac, LA Dakin, ...
New England Journal of Medicine 388 (11), 969-979, 2023
542023
Structural basis for UBA-mediated dimerization of c-Cbl ubiquitin ligase
G Kozlov, P Peschard, B Zimmerman, T Lin, T Moldoveanu, ...
Journal of Biological Chemistry 282 (37), 27547-27555, 2007
532007
Src-dependent phosphorylation of β2-adaptin dissociates the β-arrestin–AP-2 complex
D Fessart, M Simaan, B Zimmerman, J Comeau, FF Hamdan, ...
Journal of cell science 120 (10), 1723-1732, 2007
522007
Role of ssarrestins in bradykinin B2 receptor-mediated signalling
B Zimmerman, M Simaan, MY Akoume, N Houri, S Chevallier, P Séguéla, ...
Cellular signalling 23 (4), 648-659, 2011
512011
Structure of human POFUT1, its requirement in ligand-independent oncogenic Notch signaling, and functional effects of Dowling-Degos mutations
BJ McMillan, B Zimmerman, ED Egan, M Lofgren, X Xu, A Hesser, ...
Glycobiology 27 (8), 777-786, 2017
492017
A tail of two sites: a bipartite mechanism for recognition of notch ligands by mind bomb E3 ligases
B McMillan, B Schnute, N Ohlenhard, B Zimmerman, M Laura, N Beglova, ...
Molecular Cell 57 (5), 912-924, 2015
402015
Essential role of endocytosis of the type II transmembrane serine protease TMPRSS6 in regulating its functionality
F Béliveau, C Brulé, A Désilets, B Zimmerman, SA Laporte, CL Lavoie, ...
Journal of Biological Chemistry 286 (33), 29035-29043, 2011
282011
Biasing the prostaglandin F2α receptor responses toward EGFR-dependent transactivation of MAPK
E Goupil, V Wisehart, E Khoury, B Zimmerman, S Jaffal, TE Hébert, ...
Molecular Endocrinology 26 (7), 1189-1202, 2012
272012
Crystal structure of human tetraspanin CD81 reveals a conserved intramembrane binding cavity
B Zimmerman, B McMillan, T Seegar, A Kruse, S Blacklow
The FASEB Journal 30, lb71-lb71, 2016
62016
Arrestin biosensor
M Bouvier, PG Charest, C LeGouill, A Beautrait, SA Laporte, ...
US Patent 8,883,486, 2014
52014
Crystal structure of human tetraspanin CD81 reveals a conserved cholesterol binding cavity
B Zimmerman, BJ McMillan, T Seegar, AC Kruse, SC Blacklow
The Journal of Immunology 196 (1_Supplement), 132.6-132.6, 2016
12016
Small Molecule APOL1 Inhibitors as a Precision Medicine Approach for APOL1-mediated Kidney Disease
B Zimmerman, L Dakin, A Fortier, E Nanou, A Blasio, J Mann, H Miller, ...
2024
Regulation of angiotension II type I receptor signalling by beta-arrestin and the clathrin adaptor AP-2
B Zimmerman
McGill University, 2012
2012
Development of small chemical tools modulating clathrin‐mediated GPCR endocytosis
A Beautrait, B Zimmerman, M Audet, S Laporte, M Bouvier
The FASEB Journal 25, 751.2-751.2, 2011
2011
The system can't perform the operation now. Try again later.
Articles 1–20