Mechanical Allostery: Evidence for a Force Requirement in the Proteolytic Activation of Notch W Gordon, B Zimmerman, L He, L Miles, J Huang, K Tiyanont, D McArthur, ... Developmental Cell 33 (6), 729-736, 2015 | 383 | 2015 |
Crystal structure of a full-length human tetraspanin reveals a cholesterol-binding pocket B Zimmerman, B Kelly, BJ McMillan, TCM Seegar, RO Dror, AC Kruse, ... Cell 167 (4), 1041-1051. e11, 2016 | 270 | 2016 |
Differential β-arrestin–dependent conformational signaling and cellular responses revealed by angiotensin analogs B Zimmerman, A Beautrait, B Aguila, R Charles, E Escher, A Claing, ... Science signaling 5 (221), ra33-ra33, 2012 | 168 | 2012 |
Structural basis for regulated proteolysis by the α-secretase ADAM10 TCM Seegar, LB Killingsworth, N Saha, PA Meyer, D Patra, B Zimmerman, ... Cell 171 (7), 1638-1648. e7, 2017 | 149 | 2017 |
A new inhibitor of the β-arrestin/AP2 endocytic complex reveals interplay between GPCR internalization and signalling A Beautrait, JS Paradis, B Zimmerman, J Giubilaro, L Nikolajev, ... Nature communications 8 (1), 15054, 2017 | 142 | 2017 |
c-Src-mediated phosphorylation of AP-2 reveals a general mechanism for receptors internalizing through the clathrin pathway B Zimmerman, M Simaan, MH Lee, LM Luttrell, SA Laporte Cellular signalling 21 (1), 103-110, 2009 | 68 | 2009 |
Inaxaplin for Proteinuric Kidney Disease in Persons with Two APOL1 Variants O Egbuna, B Zimmerman, G Manos, A Fortier, MC Chirieac, LA Dakin, ... New England Journal of Medicine 388 (11), 969-979, 2023 | 54 | 2023 |
Structural basis for UBA-mediated dimerization of c-Cbl ubiquitin ligase G Kozlov, P Peschard, B Zimmerman, T Lin, T Moldoveanu, ... Journal of Biological Chemistry 282 (37), 27547-27555, 2007 | 53 | 2007 |
Src-dependent phosphorylation of β2-adaptin dissociates the β-arrestin–AP-2 complex D Fessart, M Simaan, B Zimmerman, J Comeau, FF Hamdan, ... Journal of cell science 120 (10), 1723-1732, 2007 | 52 | 2007 |
Role of ssarrestins in bradykinin B2 receptor-mediated signalling B Zimmerman, M Simaan, MY Akoume, N Houri, S Chevallier, P Séguéla, ... Cellular signalling 23 (4), 648-659, 2011 | 51 | 2011 |
Structure of human POFUT1, its requirement in ligand-independent oncogenic Notch signaling, and functional effects of Dowling-Degos mutations BJ McMillan, B Zimmerman, ED Egan, M Lofgren, X Xu, A Hesser, ... Glycobiology 27 (8), 777-786, 2017 | 49 | 2017 |
A tail of two sites: a bipartite mechanism for recognition of notch ligands by mind bomb E3 ligases B McMillan, B Schnute, N Ohlenhard, B Zimmerman, M Laura, N Beglova, ... Molecular Cell 57 (5), 912-924, 2015 | 40 | 2015 |
Essential role of endocytosis of the type II transmembrane serine protease TMPRSS6 in regulating its functionality F Béliveau, C Brulé, A Désilets, B Zimmerman, SA Laporte, CL Lavoie, ... Journal of Biological Chemistry 286 (33), 29035-29043, 2011 | 28 | 2011 |
Biasing the prostaglandin F2α receptor responses toward EGFR-dependent transactivation of MAPK E Goupil, V Wisehart, E Khoury, B Zimmerman, S Jaffal, TE Hébert, ... Molecular Endocrinology 26 (7), 1189-1202, 2012 | 27 | 2012 |
Crystal structure of human tetraspanin CD81 reveals a conserved intramembrane binding cavity B Zimmerman, B McMillan, T Seegar, A Kruse, S Blacklow The FASEB Journal 30, lb71-lb71, 2016 | 6 | 2016 |
Arrestin biosensor M Bouvier, PG Charest, C LeGouill, A Beautrait, SA Laporte, ... US Patent 8,883,486, 2014 | 5 | 2014 |
Crystal structure of human tetraspanin CD81 reveals a conserved cholesterol binding cavity B Zimmerman, BJ McMillan, T Seegar, AC Kruse, SC Blacklow The Journal of Immunology 196 (1_Supplement), 132.6-132.6, 2016 | 1 | 2016 |
Small Molecule APOL1 Inhibitors as a Precision Medicine Approach for APOL1-mediated Kidney Disease B Zimmerman, L Dakin, A Fortier, E Nanou, A Blasio, J Mann, H Miller, ... | | 2024 |
Regulation of angiotension II type I receptor signalling by beta-arrestin and the clathrin adaptor AP-2 B Zimmerman McGill University, 2012 | | 2012 |
Development of small chemical tools modulating clathrin‐mediated GPCR endocytosis A Beautrait, B Zimmerman, M Audet, S Laporte, M Bouvier The FASEB Journal 25, 751.2-751.2, 2011 | | 2011 |