Tryptophan catabolites from microbiota engage aryl hydrocarbon receptor and balance mucosal reactivity via interleukin-22 T Zelante, RG Iannitti, C Cunha, A De Luca, G Giovannini, G Pieraccini, ... Immunity 39 (2), 372-385, 2013 | 2124 | 2013 |
Modulation of tryptophan catabolism by regulatory T cells F Fallarino, U Grohmann, KW Hwang, C Orabona, C Vacca, R Bianchi, ... Nature immunology 4 (12), 1206-1212, 2003 | 1836 | 2003 |
CTLA-4–Ig regulates tryptophan catabolism in vivo U Grohmann, C Orabona, F Fallarino, C Vacca, F Calcinaro, A Falorni, ... Nature immunology 3 (11), 1097-1101, 2002 | 1510 | 2002 |
The combined effects of tryptophan starvation and tryptophan catabolites down-regulate T cell receptor ζ-chain and induce a regulatory phenotype in naive T cells F Fallarino, U Grohmann, S You, BC McGrath, DR Cavener, C Vacca, ... The Journal of Immunology 176 (11), 6752-6761, 2006 | 1313 | 2006 |
T cell apoptosis by tryptophan catabolism F Fallarino, U Grohmann, C Vacca, R Bianchi, C Orabona, A Spreca, ... Cell Death & Differentiation 9 (10), 1069-1077, 2002 | 1206 | 2002 |
Tryptophan metabolism as a common therapeutic target in cancer, neurodegeneration and beyond M Platten, EAA Nollen, UF Röhrig, F Fallarino, CA Opitz Nature reviews Drug discovery 18 (5), 379-401, 2019 | 1070 | 2019 |
BTLA is a lymphocyte inhibitory receptor with similarities to CTLA-4 and PD-1 N Watanabe, M Gavrieli, JR Sedy, J Yang, F Fallarino, SK Loftin, ... Nature immunology 4 (7), 670-679, 2003 | 1069 | 2003 |
Tolerance, DCs and tryptophan: much ado about IDO U Grohmann, F Fallarino, P Puccetti Trends in immunology 24 (5), 242-248, 2003 | 948 | 2003 |
Indoleamine 2, 3-dioxygenase is a signaling protein in long-term tolerance by dendritic cells MT Pallotta, C Orabona, C Volpi, C Vacca, ML Belladonna, R Bianchi, ... Nature immunology 12 (9), 870-878, 2011 | 750 | 2011 |
Aryl hydrocarbon receptor control of a disease tolerance defence pathway A Bessede, M Gargaro, MT Pallotta, D Matino, G Servillo, C Brunacci, ... Nature 511 (7508), 184-190, 2014 | 699 | 2014 |
Defective tryptophan catabolism underlies inflammation in mouse chronic granulomatous disease L Romani, F Fallarino, A De Luca, C Montagnoli, C D’Angelo, T Zelante, ... Nature 451 (7175), 211-215, 2008 | 632 | 2008 |
Gut CD103+ dendritic cells express indoleamine 2, 3-dioxygenase which influences T regulatory/T effector cell balance and oral tolerance induction G Matteoli, E Mazzini, ID Iliev, E Mileti, F Fallarino, P Puccetti, M Chieppa, ... Gut 59 (5), 595-604, 2010 | 437 | 2010 |
IDO upregulates regulatory T cells via tryptophan catabolite and suppresses encephalitogenic T cell responses in experimental autoimmune encephalomyelitis Y Yan, GX Zhang, B Gran, F Fallarino, S Yu, H Li, ML Cullimore, ... The Journal of Immunology 185 (10), 5953-5961, 2010 | 387 | 2010 |
CD28 induces immunostimulatory signals in dendritic cells via CD80 and CD86 C Orabona, U Grohmann, ML Belladonna, F Fallarino, C Vacca, R Bianchi, ... Nature immunology 5 (11), 1134-1142, 2004 | 386 | 2004 |
Reverse signaling through GITR ligand enables dexamethasone to activate IDO in allergy U Grohmann, C Volpi, F Fallarino, S Bozza, R Bianchi, C Vacca, ... Nature medicine 13 (5), 579-586, 2007 | 379 | 2007 |
IL-23 and IL-12 have overlapping, but distinct, effects on murine dendritic cells ML Belladonna, JC Renauld, R Bianchi, C Vacca, F Fallarino, C Orabona, ... The Journal of Immunology 168 (11), 5448-5454, 2002 | 361 | 2002 |
Functional expression of indoleamine 2, 3-dioxygenase by murine CD8α+ dendritic cells F Fallarino, C Vacca, C Orabona, ML Belladonna, R Bianchi, B Marshall, ... International Immunology 14 (1), 65-68, 2002 | 332 | 2002 |
IL-22 defines a novel immune pathway of antifungal resistance A De Luca, T Zelante, C D'Angelo, S Zagarella, F Fallarino, A Spreca, ... Mucosal immunology 3 (4), 361-373, 2010 | 320 | 2010 |
TLRs govern neutrophil activity in aspergillosis S Bellocchio, S Moretti, K Perruccio, F Fallarino, S Bozza, C Montagnoli, ... The Journal of Immunology 173 (12), 7406-7415, 2004 | 312 | 2004 |
Murine plasmacytoid dendritic cells initiate the immunosuppressive pathway of tryptophan catabolism in response to CD200 receptor engagement F Fallarino, C Asselin-Paturel, C Vacca, R Bianchi, S Gizzi, MC Fioretti, ... The Journal of Immunology 173 (6), 3748-3754, 2004 | 311 | 2004 |