| Structural repertoire of HIV-1-neutralizing antibodies targeting the CD4 supersite in 14 donors T Zhou, RM Lynch, L Chen, P Acharya, X Wu, NA Doria-Rose, MG Joyce, ... Cell 161 (6), 1280-1292, 2015 | 315 | 2015 |
| Origins of specificity and affinity in antibody–protein interactions HP Peng, KH Lee, JW Jian, AS Yang Proceedings of the National Academy of Sciences 111 (26), E2656-E2665, 2014 | 206 | 2014 |
| Germline breast cancer susceptibility gene mutations and breast cancer outcomes YA Wang, JW Jian, CF Hung, HP Peng, CF Yang, HCS Cheng, AS Yang BMC cancer 18, 1-13, 2018 | 95 | 2018 |
| Rationalization and design of the complementarity determining region sequences in an antibody-antigen recognition interface CM Yu, HP Peng, IC Chen, YC Lee, JB Chen, KC Tsai, CT Chen, ... PLoS One 7 (3), e33340, 2012 | 59 | 2012 |
| Amino acid substitutions of MagA in Klebsiella pneumoniae affect the biosynthesis of the capsular polysaccharide TL Lin, FL Yang, AS Yang, HP Peng, TL Li, MD Tsai, SH Wu, JT Wang PLoS One 7 (10), e46783, 2012 | 48 | 2012 |
| Modeling protein loops with knowledge-based prediction of sequence-structure alignment HP Peng, AS Yang Bioinformatics 23 (21), 2836-2842, 2007 | 43 | 2007 |
| Protein-protein interaction site predictions with three-dimensional probability distributions of interacting atoms on protein surfaces CT Chen, HP Peng, JW Jian, KC Tsai, JY Chang, EW Yang, JB Chen, ... PloS one 7 (6), e37706, 2012 | 38 | 2012 |
| Structure‐based design and synthesis of highly potent SARS‐CoV 3CL protease inhibitors YM Shao, WB Yang, HP Peng, MF Hsu, KC Tsai, TH Kuo, AHJ Wang, ... ChemBioChem 8 (14), 1654-1657, 2007 | 38 | 2007 |
| Loop-Sequence Features and Stability Determinants in Antibody Variable Domains by High-Throughput Experiments HJ Chang, JW Jian, HJ Hsu, YC Lee, HS Chen, JJ You, SC Hou, CY Shao, ... Structure 22 (1), 9-21, 2014 | 36 | 2014 |
| Assessing computational amino acid β-turn propensities with a phage-displayed combinatorial library and directed evolution HJ Hsu, HJ Chang, HP Peng, SS Huang, MY Lin, AS Yang Structure 14 (10), 1499-1510, 2006 | 32 | 2006 |
| Prediction of carbohydrate binding sites on protein surfaces with 3-dimensional probability density distributions of interacting atoms KC Tsai, JW Jian, EW Yang, PC Hsu, HP Peng, CT Chen, JB Chen, ... PloS one 7 (7), e40846, 2012 | 30 | 2012 |
| Antibody variable domain interface and framework sequence requirements for stability and function by high-throughput experiments HJ Hsu, KH Lee, JW Jian, HJ Chang, CM Yu, YC Lee, C Chen, HP Peng, ... Structure 22 (1), 22-34, 2014 | 29 | 2014 |
| Discovering neutralizing antibodies targeting the stem epitope of H1N1 influenza hemagglutinin with synthetic phage-displayed antibody libraries CP Tung, IC Chen, CM Yu, HP Peng, JW Jian, SH Ma, YC Lee, JT Jan, ... Scientific Reports 5 (1), 15053, 2015 | 20 | 2015 |
| Molecular evolution of cystine-stabilized miniproteins as stable proteinaceous binders HJ Chang, HJ Hsu, C Chang, HP Peng, YK Sun, HM Yu, HC Shih, ... Structure 17 (4), 620-631, 2009 | 18 | 2009 |
| Predicting ligand binding sites on protein surfaces by 3-dimensional probability density distributions of interacting atoms JW Jian, P Elumalai, T Pitti, CY Wu, KC Tsai, JY Chang, HP Peng, ... PloS one 11 (8), e0160315, 2016 | 17 | 2016 |
| Predominant structural configuration of natural antibody repertoires enables potent antibody responses against protein antigens HS Chen, SC Hou, JW Jian, KS Goh, ST Shen, YC Lee, JJ You, HP Peng, ... Scientific reports 5 (1), 12411, 2015 | 17 | 2015 |
| Evaluating BRCA mutation risk predictive models in a Chinese cohort in Taiwan FH Hung, YA Wang, JW Jian, HP Peng, LL Hsieh, CF Hung, MM Yang, ... Scientific Reports 9 (1), 10229, 2019 | 16 | 2019 |
| Effective binding to protein antigens by antibodies from antibody libraries designed with enhanced protein recognition propensities JW Jian, HS Chen, YK Chiu, HP Peng, CP Tung, IC Chen, CM Yu, ... mAbs 11 (2), 373-387, 2019 | 14 | 2019 |
| Antibody-drug conjugates with HER2-targeting antibodies from synthetic antibody libraries are highly potent against HER2-positive human gastric tumor in xenograft models WY Kuo, HJ Hsu, CY Wu, HS Chen, YC Chou, YL Tsou, HP Peng, ... mAbs 11 (1), 153-165, 2019 | 10 | 2019 |
| Prediction of fatty acid-binding residues on protein surfaces with three-dimensional probability distributions of interacting atoms R Mahalingam, HP Peng, AS Yang Biophysical chemistry 192, 10-19, 2014 | 10 | 2014 |
An-Suei YangGenomics Research Center, Academia SinicaEmail verificata su gate.sinica.edu.tw
