Genomics Research Center, Academia Sinica
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Structural repertoire of HIV-1-neutralizing antibodies targeting the CD4 supersite in 14 donors
T Zhou, RM Lynch, L Chen, P Acharya, X Wu, NA Doria-Rose, MG Joyce, ...
Cell 161 (6), 1280-1292, 2015
Origins of specificity and affinity in antibody–protein interactions
HP Peng, KH Lee, JW Jian, AS Yang
Proceedings of the National Academy of Sciences 111 (26), E2656-E2665, 2014
Rationalization and design of the complementarity determining region sequences in an antibody-antigen recognition interface
CM Yu, HP Peng, IC Chen, YC Lee, JB Chen, KC Tsai, CT Chen, ...
PLoS One 7 (3), e33340, 2012
Modeling protein loops with knowledge-based prediction of sequence-structure alignment
HP Peng, AS Yang
Bioinformatics 23 (21), 2836-2842, 2007
Amino acid substitutions of MagA in Klebsiella pneumoniae affect the biosynthesis of the capsular polysaccharide
TL Lin, FL Yang, AS Yang, HP Peng, TL Li, MD Tsai, SH Wu, JT Wang
PLoS One 7 (10), 2012
Protein-protein interaction site predictions with three-dimensional probability distributions of interacting atoms on protein surfaces
CT Chen, HP Peng, JW Jian, KC Tsai, JY Chang, EW Yang, JB Chen, ...
PloS one 7 (6), 2012
Structure‐Based Design and Synthesis of Highly Potent SARS‐CoV 3CL Protease Inhibitors
YM Shao, WB Yang, HP Peng, MF Hsu, KC Tsai, TH Kuo, AHJ Wang, ...
ChemBioChem 8 (14), 1654-1657, 2007
Germline breast cancer susceptibility gene mutations and breast cancer outcomes
YA Wang, JW Jian, CF Hung, HP Peng, CF Yang, HCS Cheng, AS Yang
BMC cancer 18 (1), 315, 2018
Loop-Sequence Features and Stability Determinants in Antibody Variable Domains by High-Throughput Experiments
HJ Chang, JW Jian, HJ Hsu, YC Lee, HS Chen, JJ You, SC Hou, CY Shao, ...
Structure 22 (1), 9-21, 2014
Prediction of carbohydrate binding sites on protein surfaces with 3-dimensional probability density distributions of interacting atoms
KC Tsai, JW Jian, EW Yang, PC Hsu, HP Peng, CT Chen, JB Chen, ...
PLoS One 7 (7), 2012
Assessing computational amino acid β-turn propensities with a phage-displayed combinatorial library and directed evolution
HJ Hsu, HJ Chang, HP Peng, SS Huang, MY Lin, AS Yang
Structure 14 (10), 1499-1510, 2006
Antibody variable domain interface and framework sequence requirements for stability and function by high-throughput experiments
HJ Hsu, KH Lee, JW Jian, HJ Chang, CM Yu, YC Lee, C Chen, HP Peng, ...
Structure 22 (1), 22-34, 2014
Molecular evolution of cystine-stabilized miniproteins as stable proteinaceous binders
HJ Chang, HJ Hsu, C Chang, HP Peng, YK Sun, HM Yu, HC Shih, ...
Structure 17 (4), 620-631, 2009
Discovering neutralizing antibodies targeting the stem epitope of H1N1 influenza hemagglutinin with synthetic phage-displayed antibody libraries
CP Tung, C Chen, CM Yu, HP Peng, JW Jian, SH Ma, YC Lee, JT Jan, ...
Scientific reports 5 (1), 1-16, 2015
Predominant structural configuration of natural antibody repertoires enables potent antibody responses against protein antigens
HS Chen, SC Hou, JW Jian, KS Goh, ST Shen, YC Lee, JJ You, HP Peng, ...
Scientific reports 5, 12411, 2015
Prediction of fatty acid-binding residues on protein surfaces with three-dimensional probability distributions of interacting atoms
R Mahalingam, HP Peng, AS Yang
Biophysical chemistry 192, 10-19, 2014
Prediction of FMN-binding residues with three-dimensional probability distributions of interacting atoms on protein surfaces
R Mahalingam, HP Peng, AS Yang
Journal of theoretical biology 343, 154-161, 2014
Predicting ligand binding sites on protein surfaces by 3-dimensional probability density distributions of interacting atoms
JW Jian, P Elumalai, T Pitti, CY Wu, KC Tsai, JY Chang, HP Peng, ...
PloS one 11 (8), 2016
Antibody-drug conjugates with HER2-targeting antibodies from synthetic antibody libraries are highly potent against HER2-positive human gastric tumor in xenograft models
WY Kuo, HJ Hsu, CY Wu, HS Chen, YC Chou, YL Tsou, HP Peng, ...
mAbs 11 (1), 153-165, 2019
Evaluating BRCA mutation risk predictive models in a Chinese cohort in Taiwan
FH Hung, YA Wang, JW Jian, HP Peng, LL Hsieh, CF Hung, MM Yang, ...
Scientific reports 9 (1), 1-10, 2019
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