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Rikke Hahn Kofoed
Rikke Hahn Kofoed
Post doctoral fellow, Aarhus University and Aarhus University Hospital, Denmark
Email verificata su sri.utoronto.ca
Titolo
Citata da
Citata da
Anno
Alpha‐synuclein aggregates activate calcium pump SERCA leading to calcium dysregulation
C Betzer, LB Lassen, A Olsen, RH Kofoed, L Reimer, E Gregersen, ...
EMBO reports 19 (5), e44617, 2018
1052018
ELISA method to detect α-synuclein oligomers in cell and animal models
LB Lassen, E Gregersen, AK Isager, C Betzer, RH Kofoed, PH Jensen
PloS one 13 (4), e0196056, 2018
662018
Focused ultrasound as a novel strategy for noninvasive gene delivery to retinal Müller glia
Y Touahri, R Dixit, RH Kofoed, K Mikloska, EJ Park, R Raeisossadati, ...
Theranostics 10 (7), 2982, 2020
262020
Strategy to enhance transgene expression in proximity of amyloid plaques in a mouse model of Alzheimer's disease
D Weber-Adrian, RH Kofoed, JWY Chan, J Silburt, Z Noroozian, S Kügler, ...
Theranostics 9 (26), 8127, 2019
252019
Inflammation kinase PKR phosphorylates α-synuclein and causes α-synuclein-dependent cell death
L Reimer, LB Vesterager, C Betzer, J Zheng, LD Nielsen, RH Kofoed, ...
Neurobiology of disease 115, 17-28, 2018
242018
PKR kinase directly regulates tau expression and Alzheimer's disease‐related tau phosphorylation
L Reimer, C Betzer, RH Kofoed, C Volbracht, K Fog, C Kurhade, E Nilsson, ...
Brain Pathology 31 (1), 103-119, 2021
232021
Polo-like kinase 2 modulates α-synuclein protein levels by regulating its mRNA production
RH Kofoed, J Zheng, N Ferreira, S Lykke-Andersen, M Salvi, C Betzer, ...
Neurobiology of disease 106, 49-62, 2017
222017
Ultrasound delivery of a TrkA agonist confers neuroprotection to Alzheimer-associated pathologies
K Xhima, K Markham-Coultes, R Hahn Kofoed, HU Saragovi, K Hynynen, ...
Brain 145 (8), 2806-2822, 2022
212022
Efficacy of gene delivery to the brain using AAV and ultrasound depends on serotypes and brain areas
RH Kofoed, CL Dibia, K Noseworthy, K Xhima, N Vacaresse, K Hynynen, ...
Journal of Controlled Release 351, 667-680, 2022
192022
Systemic AAV6-synapsin-GFP administration results in lower liver biodistribution, compared to AAV1&2 and AAV9, with neuronal expression following ultrasound-mediated brain delivery
D Weber-Adrian, RH Kofoed, J Silburt, Z Noroozian, K Shah, A Burgess, ...
Scientific Reports 11 (1), 1934, 2021
142021
Glycogen synthase kinase 3 β activity is essential for Polo-like kinase 2-and Leucine-rich repeat kinase 2-mediated regulation of α-synuclein
RH Kofoed, C Betzer, N Ferreira, PH Jensen
Neurobiology of Disease 136, 104720, 2020
142020
Transgene distribution and immune response after ultrasound delivery of rAAV9 and PHP. B to the brain in a mouse model of amyloidosis
RH Kofoed, S Heinen, J Silburt, S Dubey, CL Dibia, M Maes, EM Simpson, ...
Molecular Therapy-Methods & Clinical Development 23, 390-405, 2021
122021
Viral alpha-synuclein knockdown prevents spreading synucleinopathy
S Menon, RH Kofoed, F Nabbouh, K Xhima, Y Al-Fahoum, T Langman, ...
Brain Communications 3 (4), fcab247, 2021
92021
Investigation of RNA synthesis using 5-bromouridine labelling and immunoprecipitation
RH Kofoed, C Betzer, S Lykke-Andersen, E Molska, PH Jensen
JoVE (Journal of Visualized Experiments), e57056, 2018
62018
The engineered AAV2-HBKO promotes non-invasive gene delivery to large brain regions beyond ultrasound targeted sites
RH Kofoed, K Noseworthy, K Wu, S Sivadas, L Stanek, B Elmer, ...
Molecular Therapy-Methods & Clinical Development 27, 167-184, 2022
52022
Using focused ultrasound to modulate microglial structure and function
S Grewal, E Gonçalves de Andrade, RH Kofoed, PM Matthews, I Aubert, ...
Frontiers in Cellular Neuroscience 17, 1290628, 2023
12023
Sonoselective delivery using ultrasound and microbubbles combined with intravenous rAAV9 CLDN5-GFP does not increase endothelial gene expression
RH Kofoed, EM Simpson, K Hynynen, I Aubert
Gene Therapy 30 (12), 807-811, 2023
12023
The Impact of Serotypes and Anatomical Regions on the Efficacy of Focused Ultrasound-Mediated AAV Delivery to the Brain
RH Kofoed, K Noseworthy, C Dibia, N Vacaresse, K Hynynen, I Aubert
MOLECULAR THERAPY 29 (4), 180-180, 2021
12021
The Use of Co-immunoprecipitation to Study Conformation-Specific Protein Interactions of Oligomeric α-Synuclein Aggregates
C Betzer, RH Kofoed, PH Jensen
Co-Immunoprecipitation Methods for Brain Tissue, 23-36, 2019
12019
Science around the world
P Antas, A Cleveland, P Contessotto, R Schaffrath
Trends in molecular medicine, 2024
2024
Il sistema al momento non può eseguire l'operazione. Riprova più tardi.
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