NPE Vermeulen
NPE Vermeulen
Hoogleraar VU
Email verificata su vu.nl
Titolo
Citata da
Citata da
Anno
Fish bioaccumulation and biomarkers in environmental risk assessment: a review
R Van der Oost, J Beyer, NPE Vermeulen
Environmental toxicology and pharmacology 13 (2), 57-149, 2003
48372003
Membrane transporters in drug development
KM Giacomini, SM Huang, DJ Tweedie, LZ Benet, KLR Brouwer, X Chu, ...
Nature reviews Drug discovery 9 (3), 215, 2010
27452010
Biomarkers of free radical damage: applications in experimental animals and in humans
LL de Zwart, JHN Meerman, JNM Commandeur, NPE Vermeulen
Free Radical Biology and Medicine 26 (1-2), 202-226, 1999
12151999
Paracetamol (acetaminophen)-induced toxicity: molecular and biochemical mechanisms, analogues and protective approaches
JGM Bessems, NPE Vermeulen
Critical reviews in toxicology 31 (1), 55-138, 2001
8172001
Enzyme-catalyzed activation of anticancer prodrugs
M Rooseboom, JNM Commandeur, NPE Vermeulen
Pharmacological reviews 56 (1), 53-102, 2004
5802004
Enzymes and transport systems involved in the formation and disposition of glutathione S-conjugates. Role in bioactivation and detoxication mechanisms of xenobiotics
JNM Commandeur
Pharmacol Rev. 47, 271-330, 1995
4171995
Molecular aspects of paracetamol-induced hepatotoxicity and its mechanism-based prevention
NPE Vermeulen, JGM Bessems, R Van de Straat
Drug metabolism reviews 24 (3), 367-407, 1992
4151992
Genetic Polymorphisms of Human N-Acetyltransferase, Cytochrome P450, Glutathione-S-Transferase, and Epoxide Hydrolase Enzymes: Relevance to Xenobiotic …
LW Wormhoudt, JNM Commandeur, NPE Vermeulen
Critical reviews in toxicology 29 (1), 59-124, 1999
4061999
Managing the challenge of chemically reactive metabolites in drug development
BK Park, A Boobis, S Clarke, CEP Goldring, D Jones, JG Kenna, ...
Nature Reviews Drug Discovery 10 (4), 292-306, 2011
4052011
Oxygen and xenobiotic reductase activities of cytochrome P450
AR Goeptar, H Scheerens, NPE Vermeulen
Critical reviews in toxicology 25 (1), 25-65, 1995
3511995
Effects of curcumin on cytochrome P450 and glutathione S-transferase activities in rat liver
S Oetari, M Sudibyo, JNM Commandeur, R Samhoedi, NPE Vermeulen
Biochemical pharmacology 51 (1), 39-45, 1996
2851996
Cytochrome P450 in silico: an integrative modeling approach
C De Graaf, NPE Vermeulen, KA Feenstra
Journal of medicinal chemistry 48 (8), 2725-2755, 2005
2612005
Biomonitoring of aquatic pollution with feral eel (Anguilla anguilla) II. Biomarkers: pollution-induced biochemical responses
R van der Oost, A Goksøyr, M Celander, H Heida, NPE Vermeulen
Aquatic Toxicology 36 (3-4), 189-222, 1996
2331996
Variability in nifedipine pharmacokinetics and dynamics: a new oxidation polymorphism in man
CH Kleinbloesem, P Van Brummelen, H Faber, M Danhof, ...
Biochemical pharmacology 33 (22), 3721-3724, 1984
2151984
A predictive model for substrates of cytochrome P450-debrisoquine (2D6)
L Koymans, NPE Vermeulen, SABE Van Acker, JM Te Koppele, ...
Chemical research in toxicology 5 (2), 211-219, 1992
2041992
Mercapturic acids, protein adducts, and DNA adducts as biomarkers of electrophilic chemicals
RTH van Welie, RGJM van Dijck, NPE Vermeulen, NJ van Sittert
Critical reviews in toxicology 22 (5-6), 271-306, 1992
1791992
Cytotoxic and cytoprotective activities of curcumin: effects on paracetamol-induced cytotoxicity, lipid peroxidation and glutathione depletion in rat hepatocytes
IA Donatus, NPE Vermeulen
Biochemical pharmacology 39 (12), 1869-1875, 1990
1701990
Inhibition of human recombinant cytochrome P450s by curcumin and curcumin decomposition products
R Appiah-Opong, JNM Commandeur, B van Vugt-Lussenburg, ...
Toxicology 235 (1-2), 83-91, 2007
1682007
The role of water molecules in computational drug design
S de Beer, NPE Vermeulen, C Oostenbrink
Current topics in medicinal chemistry 10 (1), 55-66, 2010
1612010
Catalytic site prediction and virtual screening of cytochrome P450 2D6 substrates by consideration of water and rescoring in automated docking
C de Graaf, C Oostenbrink, PHJ Keizers, T van der Wijst, A Jongejan, ...
Journal of medicinal chemistry 49 (8), 2417-2430, 2006
1612006
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