| Fish bioaccumulation and biomarkers in environmental risk assessment: a review R Van der Oost, J Beyer, NPE Vermeulen Environmental toxicology and pharmacology 13 (2), 57-149, 2003 | 5985 | 2003 |
| Membrane transporters in drug development Nature reviews Drug discovery 9 (3), 215-236, 2010 | 3481 | 2010 |
| Biomarkers of free radical damage: applications in experimental animals and in humans LL de Zwart, JHN Meerman, JNM Commandeur, NPE Vermeulen Free Radical Biology and Medicine 26 (1-2), 202-226, 1999 | 1431 | 1999 |
| Paracetamol (acetaminophen)-induced toxicity: molecular and biochemical mechanisms, analogues and protective approaches JGM Bessems, NPE Vermeulen Critical reviews in toxicology 31 (1), 55-138, 2001 | 990 | 2001 |
| Enzyme-catalyzed activation of anticancer prodrugs M Rooseboom, JNM Commandeur, NPE Vermeulen Pharmacological reviews 56 (1), 53-102, 2004 | 654 | 2004 |
| Molecular aspects of paracetamol-induced hepatotoxicity and its mechanism-based prevention NPE Vermeulen, JGM Bessems, R Van de Straat Drug metabolism reviews 24 (3), 367-407, 1992 | 481 | 1992 |
| Managing the challenge of chemically reactive metabolites in drug development BK Park, A Boobis, S Clarke, CEP Goldring, D Jones, JG Kenna, ... Nature Reviews Drug Discovery 10 (4), 292-306, 2011 | 479 | 2011 |
| Enzymes and transport systems involved in the formation and disposition of glutathione S-conjugates. Role in bioactivation and detoxication mechanisms of xenobiotics JN Commandeur, GJ Stijntjes, NP Vermeulen Pharmacological reviews 47 (2), 271-330, 1995 | 466 | 1995 |
| Genetic Polymorphisms of Human N-Acetyltransferase, Cytochrome P450, Glutathione-S-Transferase, and Epoxide Hydrolase Enzymes: Relevance to Xenobiotic … LW Wormhoudt, JNM Commandeur, NPE Vermeulen Critical reviews in toxicology 29 (1), 59-124, 1999 | 449 | 1999 |
| Oxygen and xenobiotic reductase activities of cytochrome P450 AR Goeptar, H Scheerens, NPE Vermeulen Critical reviews in toxicology 25 (1), 25-65, 1995 | 386 | 1995 |
| Effects of curcumin on cytochrome P450 and glutathione S-transferase activities in rat liver S Oetari, M Sudibyo, JNM Commandeur, R Samhoedi, NPE Vermeulen Biochemical pharmacology 51 (1), 39-45, 1996 | 325 | 1996 |
| Cytochrome P450 in silico: an integrative modeling approach C De Graaf, NPE Vermeulen, KA Feenstra Journal of medicinal chemistry 48 (8), 2725-2755, 2005 | 277 | 2005 |
| Biomonitoring of aquatic pollution with feral eel (Anguilla anguilla) II. Biomarkers: pollution-induced biochemical responses R van der Oost, A Goksøyr, M Celander, H Heida, NPE Vermeulen Aquatic toxicology 36 (3-4), 189-222, 1996 | 249 | 1996 |
| Variability in nifedipine pharmacokinetics and dynamics: a new oxidation polymorphism in man CH Kleinbloesem, P Van Brummelen, H Faber, M Danhof, ... Biochemical pharmacology 33 (22), 3721-3724, 1984 | 220 | 1984 |
| A predictive model for substrates of cytochrome P450-debrisoquine (2D6) L Koymans, NPE Vermeulen, SABE Van Acker, JM Te Koppele, ... Chemical research in toxicology 5 (2), 211-219, 1992 | 217 | 1992 |
| Inhibition of human recombinant cytochrome P450s by curcumin and curcumin decomposition products R Appiah-Opong, JNM Commandeur, B van Vugt-Lussenburg, ... Toxicology 235 (1-2), 83-91, 2007 | 216 | 2007 |
| The role of water molecules in computational drug design S de Beer, NPE Vermeulen, C Oostenbrink Current topics in medicinal chemistry 10 (1), 55-66, 2010 | 198 | 2010 |
| Mercapturic acids, protein adducts, and DNA adducts as biomarkers of electrophilic chemicals RTH van Welie, RGJM van Dijck, NPE Vermeulen, NJ van Sittert Critical reviews in toxicology 22 (5-6), 271-306, 1992 | 193 | 1992 |
| Cytotoxic and cytoprotective activities of curcumin: effects on paracetamol-induced cytotoxicity, lipid peroxidation and glutathione depletion in rat hepatocytes IA Donatus, NPE Vermeulen Biochemical pharmacology 39 (12), 1869-1875, 1990 | 193 | 1990 |
| Catalytic site prediction and virtual screening of cytochrome P450 2D6 substrates by consideration of water and rescoring in automated docking C De Graaf, C Oostenbrink, PHJ Keizers, T Van Der Wijst, A Jongejan, ... Journal of medicinal chemistry 49 (8), 2417-2430, 2006 | 172 | 2006 |
