| Development of an Orally Available and Central Nervous System (CNS) Penetrant Toxoplasma gondii Calcium-Dependent Protein Kinase 1 (TgCDPK1) Inhibitor with … RSR Vidadala, KL Rivas, KK Ojo, MA Hulverson, JA Zambriski, I Bruzual, ... Journal of medicinal chemistry 59 (13), 6531-6546, 2016 | 90 | 2016 |
| Small-molecule inhibition of human immunodeficiency virus type 1 replication by targeting the interaction between Vif and ElonginC T Zuo, D Liu, W Lv, X Wang, J Wang, M Lv, W Huang, J Wu, H Zhang, ... Journal of virology 86 (10), 5497-5507, 2012 | 88 | 2012 |
| Novel bumped kinase inhibitors are safe and effective therapeutics in the calf clinical model for cryptosporidiosis DA Schaefer, DP Betzer, KD Smith, ZG Millman, HC Michalski, ... The Journal of infectious diseases 214 (12), 1856-1864, 2016 | 68 | 2016 |
| Indolizine Derivatives as HIV‐1 VIF–Elongin C Interaction Inhibitors W Huang, T Zuo, X Luo, H Jin, Z Liu, Z Yang, X Yu, L Zhang, L Zhang Chemical biology & drug design 81 (6), 730-741, 2013 | 62 | 2013 |
| Potent and selective inhibitors of CDPK1 from T. gondii and C. parvum based on a 5-aminopyrazole-4-carboxamide scaffold Z Zhang, KK Ojo, RSR Vidadala, W Huang, JA Geiger, S Scheele, R Choi, ... ACS medicinal chemistry letters 5 (1), 40-44, 2014 | 60 | 2014 |
| Design, synthesis and biological evaluation of indolizine derivatives as HIV-1 VIF–ElonginC interaction inhibitors W Huang, T Zuo, H Jin, Z Liu, Z Yang, X Yu, L Zhang, L Zhang Molecular diversity 17 (2), 221-243, 2013 | 53 | 2013 |
| Comparative study of hepatotoxicity of pyrrolizidine alkaloids retrorsine and monocrotaline X Yang, W Li, Y Sun, X Guo, W Huang, Y Peng, J Zheng Chemical Research in Toxicology 30 (2), 532-539, 2017 | 50 | 2017 |
| Necessity of Bumped Kinase Inhibitor Gastrointestinal Exposure in Treating Cryptosporidium Infection SLM Arnold, R Choi, MA Hulverson, DA Schaefer, S Vinayak, ... The Journal of Infectious Diseases 216 (1), 55-63, 2017 | 46 | 2017 |
| Optimization of Methionyl tRNA-Synthetase Inhibitors for Treatment of Cryptosporidium Infection FS Buckner, RM Ranade, JR Gillespie, S Shibata, MA Hulverson, Z Zhang, ... Antimicrobial Agents and Chemotherapy 63 (4), 10.1128/aac. 02061-18, 2019 | 41 | 2019 |
| Bumped Kinase Inhibitors as therapy for apicomplexan parasitic diseases: lessons learned R Choi, MA Hulverson, W Huang, RSR Vidadala, GR Whitman, LK Barrett, ... International journal for parasitology 50 (5), 413-422, 2020 | 40 | 2020 |
| SAR Studies of 5-Aminopyrazole-4-carboxamide Analogues as Potent and Selective Inhibitors of Toxoplasma gondii CDPK1 W Huang, KK Ojo, Z Zhang, K Rivas, RSR Vidadala, S Scheele, ... ACS medicinal chemistry letters 6 (12), 1184-1189, 2015 | 37 | 2015 |
| Development of methionyl-tRNA synthetase inhibitors as antibiotics for Gram-positive bacterial infections O Faghih, Z Zhang, RM Ranade, JR Gillespie, SA Creason, W Huang, ... Antimicrobial Agents and Chemotherapy 61 (11), 10.1128/aac. 00999-17, 2017 | 32 | 2017 |
| 5-Fluoroimidazo[4,5-b]pyridine Is a Privileged Fragment That Conveys Bioavailability to Potent Trypanosomal Methionyl-tRNA Synthetase Inhibitors Z Zhang, CY Koh, RM Ranade, S Shibata, JR Gillespie, MA Hulverson, ... ACS Infectious Diseases 2 (6), 399-404, 2016 | 32 | 2016 |
| Chemical reactivity of emodin and its oxidative metabolites to thiols B Qin, Y Xu, J Chen, W Huang, Y Peng, J Zheng Chemical Research in Toxicology 29 (12), 2114-2124, 2016 | 29 | 2016 |
| A novel calcium-dependent kinase inhibitor, bumped kinase inhibitor 1517, cures cryptosporidiosis in immunosuppressed mice A Castellanos-Gonzalez, H Sparks, S Nava, W Huang, Z Zhang, K Rivas, ... The Journal of Infectious Diseases 214 (12), 1850-1855, 2016 | 29 | 2016 |
| Development of 5-aminopyrazole-4-carboxamide-based bumped-kinase inhibitors for cryptosporidiosis therapy W Huang, MA Hulverson, R Choi, SLM Arnold, Z Zhang, MC McCloskey, ... Journal of medicinal chemistry 62 (6), 3135-3146, 2019 | 28 | 2019 |
| Structure-guided design of novel Trypanosoma brucei methionyl-tRNA synthetase inhibitors W Huang, Z Zhang, X Barros-Álvarez, CY Koh, RM Ranade, JR Gillespie, ... European journal of medicinal chemistry 124, 1081-1092, 2016 | 28 | 2016 |
| Cysteine-based protein adduction by epoxide-derived metabolite (s) of benzbromarone H Wang, Y Feng, Q Wang, X Guo, W Huang, Y Peng, J Zheng Chemical Research in Toxicology 29 (12), 2145-2152, 2016 | 25 | 2016 |
| Chemical identity of interaction of protein with reactive metabolite of Diosbulbin B in vitro and in vivo K Wang, D Lin, X Guo, W Huang, J Zheng, Y Peng Toxins 9 (8), 249, 2017 | 24 | 2017 |
| 5-Aminopyrazole-4-carboxamide analogues are selective inhibitors of Plasmodium falciparum microgametocyte exflagellation and potential malaria transmission … W Huang, MA Hulverson, Z Zhang, R Choi, KJ Hart, M Kennedy, ... Bioorganic & medicinal chemistry letters 26 (22), 5487-5491, 2016 | 19 | 2016 |
