| Mechanism of inhibition of SARS-CoV-2 M pro by N3 peptidyl Michael acceptor explained by QM/MM simulations and design of new derivatives with tunable chemical reactivity K Arafet, N Serrano-Aparicio, A Lodola, AJ Mulholland, FV González, ... Chemical Science 12 (4), 1433-1444, 2021 | 104 | 2021 |
| Design and synthesis of dipeptidyl α′, β′-epoxy ketones, potent irreversible inhibitors of the cysteine protease cruzain WR Roush, FV González, JH McKerrow, E Hansell Bioorganic & medicinal chemistry letters 8 (19), 2809-2812, 1998 | 62 | 1998 |
| Dipeptidyl Nitroalkenes as Potent Reversible Inhibitors of Cysteine Proteases Rhodesain and Cruzain ACS Med. Chem. Lett. 12, 1073-1076, 2016 | 59* | 2016 |
| Nitroepoxides as versatile precursors to 1, 4-diamino heterocycles A Vidal-Albalat, S Rodriguez, FV Gonzalez Organic letters 16 (6), 1752-1755, 2014 | 56 | 2014 |
| Facile synthesis of first generation ferrocene dendrimers by a convergent approach using ditopic conjugated dendrons J Palomero, JA Mata, F González, E Peris New Journal of Chemistry 26 (3), 291-297, 2002 | 47 | 2002 |
| A synthetic model for the [4+ 2] cycloaddition in the biosynthesis of the brevianamides, paraherquamides, and related compounds JF Sanz-Cervera, RM Williams, JA Marco, JM López-Sánchez, ... Tetrahedron 56 (34), 6345-6358, 2000 | 47 | 2000 |
| Diastereoselective additions of organolithium reagents to the C N bond of protected erythrulose oxime ethers. Synthesis of enantiopure α, α-disubstituted α-aminiacids JA Marco, M Carda, J Murga, F González, E Falomir Tetrahedron letters 38 (10), 1841-1844, 1997 | 47 | 1997 |
| Stereoisomerization of β-hydroxy-α-sulfenyl-γ-butyrolactones controlled by two concomitant 1, 4-type nonbonded sulfur− oxygen interactions as analyzed by X-ray crystallography FV González, A Jain, S Rodríguez, JA Sáez, C Vicent, G Peris The Journal of Organic Chemistry 75 (17), 5888-5894, 2010 | 46 | 2010 |
| Regioselective ring opening and isomerization reactions of 3, 4-epoxyesters catalyzed by boron trifluoride J Izquierdo, S Rodriguez, FV Gonzalez Organic Letters 13 (15), 3856-3859, 2011 | 44 | 2011 |
| Dipeptidyl-α, β-epoxyesters as potent irreversible inhibitors of the cysteine proteases cruzain and rhodesain FV González, J Izquierdo, S Rodrı, JH McKerrow, E Hansell Bioorganic & medicinal chemistry letters 17 (24), 6697-6700, 2007 | 43 | 2007 |
| Highly Stereoselective Epoxidation of α-Methyl-γ-hydroxy-α, β-unsaturated Esters: Rationalization and Synthetic Applications I López, S Rodríguez, J Izquierdo, FV González The Journal of organic chemistry 72 (17), 6614-6617, 2007 | 43 | 2007 |
| Stereoselective Synthesis of the Naturally Occurring Lactones (−)‐Osmundalactone and (−)‐Muricatacine Using Ring‐Closing Metathesis M Carda, S Rodríguez, F González, E Castillo, A Villanueva, JA Marco European Journal of Organic Chemistry 2002 (15), 2649-2655, 2002 | 43 | 2002 |
| Diastereoselectivity in organometallic additions to the carbonyl group of protected erythrulose derivatives JA Marco, M Carda, F González, S Rodríguez, E Castillo, J Murga The Journal of Organic Chemistry 63 (3), 698-707, 1998 | 41 | 1998 |
| Stereoselective synthesis of (−)-cytoxazone M Carda, F González, R Sánchez, JA Marco Tetrahedron: Asymmetry 13 (9), 1005-1010, 2002 | 39 | 2002 |
| Advances in the development of SARS-CoV-2 Mpro inhibitors L Agost-Beltrán, S de la Hoz-Rodríguez, L Bou-Iserte, S Rodríguez, ... Molecules 27 (8), 2523, 2022 | 37 | 2022 |
| Stereoselective synthesis of α-substituted serines from protected erythrulose oximes M Carda, J Murga, S Rodrı́guez, F González, E Castillo, JA Marco Tetrahedron: Asymmetry 9 (10), 1703-1712, 1998 | 37 | 1998 |
| Antiprotozoal and cysteine proteases inhibitory activity of dipeptidyl enoates S Royo, T Schirmeister, M Kaiser, S Jung, S Rodriguez, JM Bautista, ... Bioorganic & medicinal chemistry 26 (16), 4624-4634, 2018 | 34 | 2018 |
| Aldol Reactions with Erythrulose Derivatives: Stereoselective Synthesis of Differentially Protected syn-α,β-Dihydroxy Esters M Carda, J Murga, E Falomir, F González, JA Marco Tetrahedron 56 (4), 677-683, 2000 | 34 | 2000 |
| Dipeptidyl enoates as potent rhodesain inhibitors that display a dual mode of action S Royo, S Rodríguez, T Schirmeister, J Kesselring, M Kaiser, ... ChemMedChem 10 (9), 1484-1487, 2015 | 31 | 2015 |
| Dynamic kinetic asymmetric ring-opening/reductive amination sequence of racemic nitroepoxides with chiral amines: enantioselective synthesis of chiral vicinal diamines J Agut, A Vidal, S Rodríguez, FV González The Journal of Organic Chemistry 78 (11), 5717-5722, 2013 | 30 | 2013 |
