TLR5 signaling stimulates the innate production of IL-17 and IL-22 by CD3negCD127+ immune cells in spleen and mucosa L Van Maele, C Carnoy, D Cayet, P Songhet, L Dumoutier, I Ferrero, ... The Journal of Immunology 185 (2), 1177-1185, 2010 | 155 | 2010 |
Protection against Streptococcus pneumoniae serotype 1 acute infection shows a signature of Th17-and IFN-γ-mediated immunity JM Marqués, A Rial, N Muñoz, FX Pellay, L Van Maele, H Léger, T Camou, ... Immunobiology 217 (4), 420-429, 2012 | 77 | 2012 |
Key Role for Respiratory CD103+ Dendritic Cells, IFN-γ, and IL-17 in Protection Against Streptococcus pneumoniae Infection in Response to α-Galactosylceramide S Ivanov, J Fontaine, C Paget, E Macho Fernandez, L Van Maele, ... The Journal of infectious diseases 206 (5), 723-734, 2012 | 65 | 2012 |
SUMO-1 regulates the conformational dynamics of thymine-DNA glycosylase regulatory domain and competes with its DNA binding activity C Smet-Nocca, JM Wieruszeski, H Léger, S Eilebrecht, A Benecke BMC biochemistry 12, 1-15, 2011 | 59 | 2011 |
A TDG/CBP/RARα ternary complex mediates the retinoic acid-dependent expression of DNA methylation-sensitive genes H Léger, C Smet-Nocca, A Attmane-Elakeb, S Morley-Fletcher, ... Genomics, Proteomics and Bioinformatics 12 (1), 8-18, 2014 | 32 | 2014 |
Toll-like receptor 4 orchestrates neutrophil recruitment into airways during the first hours of Bordetella pertussis infection G Moreno, A Errea, L Van Maele, R Roberts, H Léger, JC Sirard, ... Microbes and infection 15 (10-11), 708-718, 2013 | 31 | 2013 |
HMGA1-dependent and independent 7SK RNA gene regulatory activity S Eilebrecht, C Bécavin, H Léger, BJ Benecke, A Benecke RNA biology 8 (1), 143-157, 2011 | 23 | 2011 |
Ndr kinases regulate retinal interneuron proliferation and homeostasis H Léger, E Santana, NA Leu, ET Smith, WA Beltran, GD Aguirre, FC Luca Scientific Reports 8 (1), 12544, 2018 | 16 | 2018 |
Preparation of mouse retinal cryo-sections for immunohistochemistry H Léger, E Santana, WA Beltran, FC Luca JoVE (Journal of Visualized Experiments), e59683, 2019 | 12 | 2019 |
Alternative splicing of TAF6: downstream transcriptome impacts and upstream RNA splice control elements C Kamtchueng, ME Stébenne, A Delannoy, E Wilhelm, H Léger, ... PLoS One 9 (7), e102399, 2014 | 7 | 2014 |
The NDR/LATS protein kinases in neurobiology: Key regulators of cell proliferation, differentiation and migration in the ocular and central nervous system PF Santos, B Fazendeiro, FC Luca, AF Ambrósio, H Léger European Journal of Cell Biology 102 (2), 151333, 2023 | 4 | 2023 |
The Importance of Kinases in Retinal Degenerative Diseases PF Santos, AF Ambrósio, H Léger Kinases and Phosphatases 2 (1), 93-109, 2024 | | 2024 |
Sitagliptin, an anti‐diabetic drug, inhibits the pro‐inflammatory microglia reactivity via dipeptidyl peptidase‐4 (DPP4) H Léger, C Leote, L Bufano, R Boia, AR Santiago, R Fernandes, ... Acta Ophthalmologica 102, 2024 | | 2024 |
Sitagliptin, a drug for type 2 diabetes, inhibits microglia reactivity triggered by exposure to lipopolysaccharide AF Ambrosio, S Correia, L Bufano, C Leote, R Boia, AR Santiago, ... GLIA 71, E850-E850, 2023 | | 2023 |
Sitagliptin, a drug for type 2 diabetes, significantly inhibits the pro-inflammatory microglia reactivity AF Ambrósio, S Correia, L Bufano, C Leote, R Boia, AR Santiago, ... Investigative Ophthalmology & Visual Science 64 (8), 1006-1006, 2023 | | 2023 |
The Dipeptidyl Peptidase 4 (DPP-4) Inhibitor, Sitagliptin, Exerts Direct Anti-inflammatory Effects on Microglial Cells AF Ambrosio, S Correia, L Bufano, C Leote, R Boia, AR Santiago, ... EUROPEAN JOURNAL OF OPHTHALMOLOGY 33 (1), 14-15, 2023 | | 2023 |
Grandma's stress programs transgenerational transmission of hippocampal glutamatergic synaptopathy associated with stress-related responses S Morley-Fletcher, J Marrocco, H Léger, J Mairesse, ML Reynaert, ... Psychoneuroendocrinology 107, 58, 2019 | | 2019 |
NDR kinases regulate retinal development, homeostasis and gene expression HM Léger, DP Beiting, WA Beltran, GD Aguirre, F Luca Investigative Ophthalmology & Visual Science 58 (8), 353-353, 2017 | | 2017 |
Étude fonctionnelle du complexe CBP/TDG/RARα dans la régulation épigénétique de la transcription et la réparation de l’ADN: couplage entre la réparation de l’ADN, la … H Leger Lille 1, 2012 | | 2012 |
TLR5 Signaling Stimulates the Innate AB Sebbane, JC Renauld, FE Janot, J Bertout, H Leger, FP Songhet, ... | | 2010 |