A transcriptionally and functionally distinct PD-1+ CD8+ T cell pool with predictive potential in non-small-cell lung cancer treated with PD-1 blockade DS Thommen, VH Koelzer, P Herzig, A Roller, M Trefny, S Dimeloe, ... Nature medicine 24 (7), 994-1004, 2018 | 876 | 2018 |
Rapid effector function of memory CD8+ T cells requires an immediate-early glycolytic switch PM Gubser, GR Bantug, L Razik, M Fischer, S Dimeloe, G Hoenger, ... Nature immunology 14 (10), 1064-1072, 2013 | 510 | 2013 |
Memory CD8+ T cells require increased concentrations of acetate induced by stress for optimal function ML Balmer, EH Ma, GR Bantug, J Grählert, S Pfister, T Glatter, A Jauch, ... Immunity 44 (6), 1312-1324, 2016 | 309 | 2016 |
The role of 1α,25‐dihydroxyvitamin D3 and cytokines in the promotion of distinct Foxp3+and IL‐10+ CD4+ T cells Z Urry, ES Chambers, E Xystrakis, S Dimeloe, DF Richards, L Gabryšová, ... European journal of immunology 42 (10), 2697-2708, 2012 | 247 | 2012 |
Regulatory T cells, inflammation and the allergic response—the role of glucocorticoids and vitamin D S Dimeloe, A Nanzer, K Ryanna, C Hawrylowicz The Journal of steroid biochemistry and molecular biology 120 (2-3), 86-95, 2010 | 242 | 2010 |
Vitamin D and immune regulation: antibacterial, antiviral, anti-inflammatory E L Bishop, A Ismailova, S Dimeloe, M Hewison, JH White Journal of Bone and Mineral Research plus 5 (1), e10405, 2021 | 227 | 2021 |
Complement regulates nutrient influx and metabolic reprogramming during Th1 cell responses M Kolev, S Dimeloe, G Le Friec, A Navarini, G Arbore, GA Povoleri, ... Immunity 42 (6), 1033-1047, 2015 | 226 | 2015 |
Targeting metabolic symbiosis to overcome resistance to anti-angiogenic therapy L Pisarsky, R Bill, E Fagiani, S Dimeloe, RW Goosen, J Hagmann, C Hess, ... Cell reports 15 (6), 1161-1174, 2016 | 200 | 2016 |
T‐cell metabolism governing activation, proliferation and differentiation; a modular view S Dimeloe, AV Burgener, J Grählert, C Hess Immunology 150 (1), 35-44, 2017 | 191 | 2017 |
Mitochondria-endoplasmic reticulum contact sites function as immunometabolic hubs that orchestrate the rapid recall response of memory CD8+ T cells GR Bantug, M Fischer, J Grählert, ML Balmer, G Unterstab, L Develioglu, ... Immunity 48 (3), 542-555. e6, 2018 | 145 | 2018 |
Defective IL-10 expression and in vitro steroid-induced IL-17A in paediatric severe therapy-resistant asthma A Gupta, S Dimeloe, DF Richards, ES Chambers, C Black, Z Urry, ... Thorax 69 (6), 508-515, 2014 | 115 | 2014 |
Human regulatory T cells lack the cyclophosphamide‐extruding transporter ABCB 1 and are more susceptible to cyclophosphamide‐induced apoptosis S Dimeloe, C Frick, M Fischer, PM Gubser, L Razik, GR Bantug, M Ravon, ... European journal of immunology 44 (12), 3614-3620, 2014 | 95 | 2014 |
The immune-metabolic basis of effector memory CD4+ T cell function under hypoxic conditions S Dimeloe, M Mehling, C Frick, J Loeliger, GR Bantug, U Sauder, ... The Journal of Immunology 196 (1), 106-114, 2016 | 93 | 2016 |
Diapedesis-induced integrin signaling via LFA-1 facilitates tissue immunity by inducing intrinsic complement C3 expression in immune cells M Kolev, EE West, N Kunz, D Chauss, EA Moseman, J Rahman, ... Immunity 52 (3), 513-527. e8, 2020 | 69 | 2020 |
Tumor-derived TGF-β inhibits mitochondrial respiration to suppress IFN-γ production by human CD4+ T cells S Dimeloe, P Gubser, J Loeliger, C Frick, L Develioglu, M Fischer, ... Science signaling 12 (599), eaav3334, 2019 | 66 | 2019 |
JAK2-mutant hematopoietic cells display metabolic alterations that can be targeted to treat myeloproliferative neoplasms TN Rao, N Hansen, J Hilfiker, S Rai, JM Majewska, D Leković, D Gezer, ... Blood, The Journal of the American Society of Hematology 134 (21), 1832-1846, 2019 | 55 | 2019 |
Autoimmune disease and interconnections with vitamin D J Fletcher, EL Bishop, SR Harrison, A Swift, SC Cooper, SK Dimeloe, ... Endocrine connections 11 (3), 2022 | 40 | 2022 |
SDHA gain-of-function engages inflammatory mitochondrial retrograde signaling via KEAP1–Nrf2 AV Burgener, GR Bantug, BJ Meyer, R Higgins, A Ghosh, O Bignucolo, ... Nature immunology 20 (10), 1311-1321, 2019 | 39 | 2019 |
T cells producing the anti‐inflammatory cytokine IL‐10 regulate allergen‐specific T h2 responses in human airways A Faith, N Singh, S Farooque, S Dimeloe, DF Richards, H Lu, D Roberts, ... Allergy 67 (8), 1007-1013, 2012 | 36 | 2012 |
Inter‐individual differences in HLA expression can impact the CDC crossmatch G Hönger, N Krähenbühl, S Dimeloe, M Stern, S Schaub, C Hess Tissue antigens 85 (4), 260-266, 2015 | 34 | 2015 |