| The positive side of the Alzheimer’s disease amyloid cross-interactions: the case of the Aβ 1-42 peptide with tau, TTR, CysC, and ApoA1 L Ciccone, C Shi, D Di Lorenzo, AC Van Baelen, N Tonali Molecules 25 (10), 2439, 2020 | 53 | 2020 |
| β-Hairpin mimics containing a piperidine–pyrrolidine scaffold modulate the β-amyloid aggregation process preserving the monomer species S Pellegrino, N Tonali, E Erba, J Kaffy, M Taverna, A Contini, M Taylor, ... Chemical science 8 (2), 1295-1302, 2017 | 49 | 2017 |
| Natural compounds as inhibitors of transthyretin amyloidosis and neuroprotective agents: Analysis of structural data for future drug design L Ciccone, N Tonali, S Nencetti, E Orlandini Journal of Enzyme Inhibition and Medicinal Chemistry 35 (1), 1145-1162, 2020 | 41 | 2020 |
| Designed glycopeptidomimetics disrupt protein–Protein interactions mediating amyloid β-peptide aggregation and restore neuroblastoma cell viability J Kaffy, D Brinet, JL Soulier, I Correia, N Tonali, KF Fera, Y Iacone, ... Journal of Medicinal Chemistry 59 (5), 2025-2040, 2016 | 40 | 2016 |
| Structure-activity relationships of β-hairpin mimics as modulators of amyloid β-peptide aggregation N Tonali, J Kaffy, JL Soulier, ML Gelmi, E Erba, M Taverna, ... European Journal of Medicinal Chemistry 154, 280-293, 2018 | 20 | 2018 |
| Real‐Time BODIPY‐Binding Assay To Screen Inhibitors of the Early Oligomerization Process of Aβ1–42 Peptide N Tonali, VI Dodero, J Kaffy, L Hericks, S Ongeri, N Sewald ChemBioChem 21 (8), 1129-1135, 2020 | 19 | 2020 |
| Introducing sequential aza-amino acids units induces repeated β-turns and helical conformations in peptides N Tonali, I Correia, J Lesma, G Bernadat, S Ongeri, O Lequin Organic & Biomolecular Chemistry 18 (18), 3452-3458, 2020 | 13 | 2020 |
| Application of PROTAC strategy to TTR-Aβ protein-protein interaction for the development of Alzheimer’s disease drugs N Tonali, S Nencetti, E Orlandini, L Ciccone Neural Regeneration Research 16 (8), 1554-1555, 2021 | 12 | 2021 |
| Mambalgin-1 pain-relieving peptide locks the hinge between α4 and α5 helices to inhibit rat acid-sensing ion channel 1a M Salinas, P Kessler, D Douguet, D Sarraf, N Tonali, R Thai, D Servent, ... Neuropharmacology 185, 108453, 2021 | 12 | 2021 |
| Pepsin Digest of Gliadin Forms Spontaneously Amyloid‐Like Nanostructures Influencing the Expression of Selected Pro‐Inflammatory, Chemoattractant, and Apoptotic Genes in Caco‐2 … MG Herrera, F Nicoletti, M Gras, PW Dörfler, N Tonali, Y Hannappel, ... Molecular nutrition & food research 65 (16), 2100200, 2021 | 10 | 2021 |
| Monoaryl derivatives as transthyretin fibril formation inhibitors: Design, synthesis, biological evaluation and structural analysis L Ciccone, S Nencetti, N Tonali, C Fruchart-Gaillard, W Shepard, E Nuti, ... Bioorganic & Medicinal Chemistry 28 (18), 115673, 2020 | 10 | 2020 |
| Physiological metals can induce conformational changes in transthyretin structure: neuroprotection or misfolding induction? L Ciccone, N Tonali, W Shepard, S Nencetti, E Orlandini Crystals 11 (4), 354, 2021 | 9 | 2021 |
| Phenothiazine‐Biaryl‐Containing Fluorescent RGD Peptides E Ghabraie, I Kemker, N Tonali, M Ismail, VI Dodero, N Sewald Chemistry–A European Journal 26 (52), 12036-12042, 2020 | 9 | 2020 |
| β-Hairpin peptide mimics decrease human islet amyloid polypeptide (hIAPP) aggregation J Lesma, F Bizet, C Berardet, N Tonali, S Pellegrino, M Taverna, ... Frontiers in Cell and Developmental Biology 9, 729001, 2021 | 8 | 2021 |
| Towards a general synthesis of di-aza-amino acids containing peptides F Bizet, N Tonali, JL Soulier, A Oliva, J Kaffy, B Crousse, S Ongeri New Journal of Chemistry 42 (20), 17062-17072, 2018 | 8 | 2018 |
| Implementing complementary approaches to shape the mechanism of α-synuclein oligomerization as a model of amyloid aggregation M Giampà, MJ Amundarain, MG Herrera, N Tonali, VI Dodero Molecules 27 (1), 88, 2021 | 7 | 2021 |
| Introduction of polar groups on the naphthalene scaffold of molecular tongs inhibiting wild-type and mutated HIV-1 protease dimerization R Fanelli, AS Ressurreicao, L Dufau, JL Soulier, A Vidu, N Tonali, ... MedChemComm 5 (6), 719-727, 2014 | 5 | 2014 |
| Insights into the structural conformations of the tau protein in different aggregation status L Pinzi, N Bisi, C Sorbi, S Franchini, N Tonali, G Rastelli Molecules 28 (11), 4544, 2023 | 4 | 2023 |
| Antioxidant Quercetin 3-O-Glycosylated Plant Flavonols Contribute to Transthyretin Stabilization L Ciccone, N Tonali, C Fruchart-Gaillard, L Barlettani, A Rossello, A Braca, ... Crystals 12 (5), 638, 2022 | 4 | 2022 |
| Peptidotriazolamers Inhibit Aβ (1–42) Oligomerization and Cross a Blood‐Brain‐Barrier Model N Tonali, L Hericks, DC Schröder, O Kracker, R Krzemieniecki, J Kaffy, ... ChemPlusChem 86 (6), 840-851, 2021 | 4 | 2021 |
