| Tumor protein 53–induced nuclear protein 1 is a major mediator of p53 antioxidant function CE Cano, J Gommeaux, S Pietri, M Culcasi, S Garcia, M Seux, S Barelier, ... Cancer research 69 (1), 219-226, 2009 | 182 | 2009 |
| Fragment-guided design of subnanomolar β-lactamase inhibitors active in vivo O Eidam, C Romagnoli, G Dalmasso, S Barelier, E Caselli, R Bonnet, ... Proceedings of the National Academy of Sciences 109 (43), 17448-17453, 2012 | 84 | 2012 |
| Fragment-Based Deconstruction of Bcl-xL Inhibitors S Barelier, J Pons, O Marcillat, JM Lancelin, I Krimm Journal of medicinal chemistry 53 (6), 2577-2588, 2010 | 84 | 2010 |
| The recognition of identical ligands by unrelated proteins S Barelier, T Sterling, MJ O’Meara, BK Shoichet ACS chemical biology 10 (12), 2772-2784, 2015 | 76 | 2015 |
| Ligand specificity in fragment-based drug design S Barelier, J Pons, K Gehring, JM Lancelin, I Krimm Journal of medicinal chemistry 53 (14), 5256-5266, 2010 | 71 | 2010 |
| Increasing chemical space coverage by combining empirical and computational fragment screens S Barelier, O Eidam, I Fish, J Hollander, F Figaroa, R Nachane, JJ Irwin, ... ACS chemical biology 9 (7), 1528-1535, 2014 | 63 | 2014 |
| Ligand specificity, privileged substructures and protein druggability from fragment-based screening S Barelier, I Krimm Current Opinion in Chemical Biology 15 (4), 469-474, 2011 | 57 | 2011 |
| Lineage-specific viral hijacking of non-canonical E3 ubiquitin ligase cofactors in the evolution of Vif anti-APOBEC3 activity JR Kane, DJ Stanley, JF Hultquist, JR Johnson, N Mietrach, JM Binning, ... Cell reports 11 (8), 1236-1250, 2015 | 52 | 2015 |
| Roles for ordered and bulk solvent in ligand recognition and docking in two related cavities S Barelier, SE Boyce, I Fish, M Fischer, DB Goodin, BK Shoichet PLoS One 8 (7), e69153, 2013 | 29 | 2013 |
| Discovery of fragment molecules that bind the human peroxiredoxin 5 active site S Barelier, D Linard, J Pons, A Clippe, B Knoops, JM Lancelin, I Krimm PLoS One 5 (3), e9744, 2010 | 25 | 2010 |
| Substrate deconstruction and the nonadditivity of enzyme recognition S Barelier, JA Cummings, AM Rauwerdink, DS Hitchcock, JD Farelli, ... Journal of the American Chemical Society 136 (20), 7374-7382, 2014 | 24 | 2014 |
| The role of the glycine triad in human glutathione synthetase A Dinescu, TR Brown, S Barelier, TR Cundari, ME Anderson Biochemical and biophysical research communications 400 (4), 511-516, 2010 | 14 | 2010 |
| Aspartate 458 of human glutathione synthetase is important for cooperativity and active site structure TR Brown, ML Drummond, S Barelier, AS Crutchfield, A Dinescu, ... Biochemical and biophysical research communications 411 (3), 536-542, 2011 | 11 | 2011 |
| Lineage-specific viral hijacking of non-canonical E3 ubiquitin ligase cofactors in the evolution of Vif anti-APOBEC3 activity. Cell Rep 11: 1236–1250 JR Kane, DJ Stanley, JF Hultquist, JR Johnson, N Mietrach, JM Binning, ... | 5 | 2015 |
| Structure-guided optimization of adenosine mimetics as selective and potent inhibitors of coronavirus nsp14 N7-methyltransferases M Hausdorff, A Delpal, S Barelier, L Nicollet, B Canard, F Touret, ... European Journal of Medicinal Chemistry 256, 115474, 2023 | 3 | 2023 |
| Direct capture, inhibition and crystal structure of HsaD (Rv3569c) from M. tuberculosis S Barelier, R Avellan, GR Gnawali, P Fourquet, V Roig‐Zamboni, I Poncin, ... The FEBS Journal 290 (6), 1563-1582, 2023 | 2 | 2023 |
| Molecular basis for substrate recognition and septum cleavage by AtlA, the major N-acetylglucosaminidase of Enterococcus faecalis V Roig-Zamboni, S Barelier, R Dixon, NF Galley, A Ghanem, QP Nguyen, ... Journal of Biological Chemistry 298 (5), 2022 | 2 | 2022 |
| The long-awaited structure of human fucosidase FucA1 opens novel avenues for the treatment of fucosidosis S Barelier, G Sulzenbacher Structure 30 (10), 1369-1371, 2022 | 1 | 2022 |
| Probing protein-small molecule interactions by Nuclear Magnetic Resonance: towards a better understanding of the Fragment-Based Drug Design methodology S Barelier Lyon 1, 2010 | 1 | 2010 |
| ChemoDOTS: a web server to design chemistry-driven focused libraries L Hoffer, G Charifi-Hoareau, S Barelier, S Betzi, T Miller, X Morelli, ... Nucleic Acids Research, gkae326, 2024 | | 2024 |
Brian ShoichetProfessor of Pharmaceutical Chemistry, University of California, San FranciscoVerified email at cgl.ucsf.edu
