Dr. Sugunadevi Sakkiah
Dr. Sugunadevi Sakkiah
U.S. FDA - National Center for Toxicology Research
Email verificata su chem.ucla.edu - Home page
Titolo
Citata da
Citata da
Anno
3D QSAR pharmacophore based virtual screening and molecular docking for identification of potential HSP90 inhibitors
S Sakkiah, S Thangapandian, S John, YJ Kwon, KW Lee
European journal of medicinal chemistry 45 (6), 2132-2140, 2010
1232010
FOXC1 Activates Smoothened-Independent Hedgehog Signalling in Basal-like Breast Cancer
CX Han B, Qu Y, Jin Y, Yu Y, Deng N, Wawrowsky K, Zhang X, Li N, Bose S ...
Cell Reports 5 (13), 1046-1058, 2015
89*2015
Potent bace-1 inhibitor design using pharmacophore modeling, in silico screening and molecular docking studies
S John, S Thangapandian, S Sakkiah, KW Lee
BMC bioinformatics 12 (S1), S28, 2011
832011
Homology modeling, molecular dynamics, e-pharmacophore mapping and docking study of Chikungunya virus nsP2 protease
KD Singh, P Kirubakaran, S Nagarajan, S Sakkiah, K Muthusamy, ...
Journal of molecular modeling 18 (1), 39-51, 2012
792012
Ligand and structure based pharmacophore modeling to facilitate novel histone deacetylase 8 inhibitor design
S Thangapandian, S John, S Sakkiah, KW Lee
European journal of medicinal chemistry 45 (10), 4409-4417, 2010
792010
Docking-enabled pharmacophore model for histone deacetylase 8 inhibitors and its application in anti-cancer drug discovery
T Sundarapandian, J Shalini, S Sugunadevi, LK Woo
Journal of Molecular Graphics and Modelling 29 (3), 382-395, 2010
562010
Pharmacophore-based virtual screening and density functional theory approach to identifying novel butyrylcholinesterase inhibitors
S Sakkiah, KW Lee
Acta Pharmacologica Sinica 33 (7), 964-978, 2012
552012
Pharmacophore based virtual screening, molecular docking studies to design potent heat shock protein 90 inhibitors
S Sakkiah, S Thangapandian, S John, KW Lee
European Journal of Medicinal Chemistry 46 (7), 2937-2947, 2011
522011
Molecular docking and pharmacophore filtering in the discovery of dual-inhibitors for human leukotriene A4 hydrolase and leukotriene C4 synthase
S Thangapandian, S John, S Sakkiah, KW Lee
Journal of chemical information and modeling 51 (1), 33-44, 2011
462011
A combination of receptor-based pharmacophore modeling & QM techniques for identification of human chymase inhibitors
M Arooj, S Sakkiah, S Kim, V Arulalapperumal, KW Lee
PLoS One 8 (4), e63030, 2013
432013
An innovative strategy for dual inhibitor design and its application in dual inhibition of human thymidylate synthase and dihydrofolate reductase enzymes
M Arooj, S Sakkiah, G Ping Cao, KW Lee
PLoS One 8 (4), e60470, 2013
412013
Identification of inhibitor binding site in human sirtuin 2 using molecular docking and dynamics simulations
S Sakkiah, M Arooj, MR Kumar, SH Eom, KW Lee
PLoS One 8 (1), e51429, 2013
412013
Potential virtual lead identification in the discovery of renin inhibitors: Application of ligand and structure-based pharmacophore modeling approaches
S Thangapandian, S John, S Sakkiah, KW Lee
European journal of medicinal chemistry 46 (6), 2469-2476, 2011
412011
Experimental data extraction and in silico prediction of the estrogenic activity of renewable replacements for bisphenol A
H Hong, BG Harvey, GR Palmese, JF Stanzione, HW Ng, S Sakkiah, ...
International journal of environmental research and public health 13 (7), 705, 2016
312016
Identification of potent virtual leads to design novel indoleamine 2, 3-dioxygenase inhibitors: Pharmacophore modeling and molecular docking studies
S John, S Thangapandian, S Sakkiah, KW Lee
European journal of medicinal chemistry 45 (9), 4004-4012, 2010
312010
Molecular dynamics simulations and applications in computational toxicology and nanotoxicology
C Selvaraj, S Sakkiah, W Tong, H Hong
Food and Chemical Toxicology 112, 495-506, 2018
302018
Pharmacophore-based virtual screening and Bayesian model for the identification of potential human leukotriene A4 hydrolase inhibitors
S Thangapandian, S John, S Sakkiah, KW Lee
European journal of medicinal chemistry 46 (5), 1593-1603, 2011
302011
CoMPARA: collaborative modeling project for androgen receptor activity
K Mansouri, N Kleinstreuer, AM Abdelaziz, D Alberga, VM Alves, ...
Environmental health perspectives 128 (2), 027002, 2020
222020
Identification of critical chemical features for Aurora kinase-B inhibitors using Hip-Hop, virtual screening and molecular docking
S Sakkiah, S Thangapandian, S John, KW Lee
Journal of Molecular Structure 985 (1), 14-26, 2011
202011
Pharmacophore mapping and virtual screening for SIRT1 activators
S Sakkiah, N Krishnamoorthy, P Gajendrarao, S Thangapandian, Y Lee, ...
Bull Korean Chem Soc 30 (5), 1153, 2009
202009
Il sistema al momento non pu eseguire l'operazione. Riprova pi tardi.
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