Nicolas Lux Fawzi
Cited by
Cited by
Protein phase separation: a new phase in cell biology
S Boeynaems, S Alberti, NL Fawzi, T Mittag, M Polymenidou, F Rousseau, ...
Trends in cell biology 28 (6), 420-435, 2018
Residue-by-residue view of in vitro FUS granules that bind the C-terminal domain of RNA polymerase II
KA Burke, AM Janke, CL Rhine, NL Fawzi
Molecular cell 60 (2), 231-241, 2015
Atomic-resolution dynamics on the surface of amyloid-β protofibrils probed by solution NMR
NL Fawzi, J Ying, R Ghirlando, DA Torchia, GM Clore
Nature 480 (7376), 268-272, 2011
ALS mutations disrupt phase separation mediated by α-helical structure in the TDP-43 low-complexity C-terminal domain
AE Conicella, GH Zerze, J Mittal, NL Fawzi
Structure 24 (9), 1537-1549, 2016
Phase Separation of C9orf72 Dipeptide Repeats Perturbs Stress Granule Dynamics
S Boeynaems, E Bogaert, D Kovacs, A Konijnenberg, E Timmerman, ...
Molecular cell 65 (6), 1044-1055. e5, 2017
Phosphorylation of the FUS low‐complexity domain disrupts phase separation, aggregation, and toxicity
Z Monahan, VH Ryan, AM Janke, KA Burke, SN Rhoads, GH Zerze, ...
The EMBO journal 36 (20), 2951-2967, 2017
Structure and Dynamics of the Aβ21–30 Peptide from the Interplay of NMR Experiments and Molecular Simulations
N L. Fawzi, AH Phillips, JZ Ruscio, M Doucleff, DE Wemmer, ...
Journal of the American Chemical Society 130 (19), 6145-6158, 2008
Kinetics of amyloid β monomer-to-oligomer exchange by NMR relaxation
NL Fawzi, J Ying, DA Torchia, GM Clore
Journal of the American Chemical Society 132 (29), 9948-9951, 2010
Coarse-grained sequences for protein folding and design
S Brown, NJ Fawzi, T Head-Gordon
Proceedings of the National Academy of Sciences 100 (19), 10712-10717, 2003
Homogeneous and heterogeneous tertiary structure ensembles of amyloid-β peptides
KA Ball, AH Phillips, PS Nerenberg, NL Fawzi, DE Wemmer, ...
Biochemistry 50 (35), 7612-7628, 2011
Mechanistic view of hnRNPA2 low-complexity domain structure, interactions, and phase separation altered by mutation and arginine methylation
VH Ryan, GL Dignon, GH Zerze, CV Chabata, R Silva, AE Conicella, ...
Molecular cell 69 (3), 465-479. e7, 2018
A single N‐terminal phosphomimic disrupts TDP‐43 polymerization, phase separation, and RNA splicing
A Wang, AE Conicella, HB Schmidt, EW Martin, SN Rhoads, AN Reeb, ...
The EMBO journal 37 (5), e97452, 2018
Determining the critical nucleus and mechanism of fibril elongation of the Alzheimer’s Aβ1–40 peptide
NL Fawzi, Y Okabe, EH Yap, T Head-Gordon
Journal of molecular biology 365 (2), 535-550, 2007
Nuclear import receptor inhibits phase separation of FUS through binding to multiple sites
T Yoshizawa, R Ali, J Jiou, HYJ Fung, KA Burke, SJ Kim, Y Lin, ...
Cell 173 (3), 693-705. e22, 2018
Probing exchange kinetics and atomic resolution dynamics in high-molecular-weight complexes using dark-state exchange saturation transfer NMR spectroscopy
NL Fawzi, J Ying, DA Torchia, GM Clore
nature protocols 7 (8), 1523-1533, 2012
Mechanistic details of a protein–protein association pathway revealed by paramagnetic relaxation enhancement titration measurements
NL Fawzi, M Doucleff, JY Suh, GM Clore
Proceedings of the National Academy of Sciences 107 (4), 1379-1384, 2010
A coarse‐grained α‐carbon protein model with anisotropic hydrogen‐bonding
EH Yap, NL Fawzi, T Head‐Gordon
Proteins: Structure, Function, and Bioinformatics 70 (3), 626-638, 2008
Protofibril assemblies of the arctic, Dutch, and Flemish mutants of the Alzheimer's Aβ1–40 peptide
NL Fawzi, KL Kohlstedt, Y Okabe, T Head-Gordon
Biophysical journal 94 (6), 2007-2016, 2008
Probing the transient dark state of substrate binding to GroEL by relaxation-based solution NMR
DS Libich, NL Fawzi, J Ying, GM Clore
Proceedings of the National Academy of Sciences 110 (28), 11361-11366, 2013
Mice with endogenous TDP‐43 mutations exhibit gain of splicing function and characteristics of amyotrophic lateral sclerosis
P Fratta, P Sivakumar, J Humphrey, K Lo, T Ricketts, H Oliveira, ...
The EMBO journal 37 (11), e98684, 2018
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