| The molecular basis for selective inhibition of unconventional mRNA splicing by an IRE1-binding small molecule BCS Cross, PJ Bond, PG Sadowski, BK Jha, J Zak, JM Goodman, ... Proceedings of the National Academy of Sciences 109 (15), E869-E878, 2012 | 577 | 2012 |
| New insights into the role of RNase L in innate immunity A Chakrabarti, BK Jha, RH Silverman Journal of Interferon & Cytokine Research 31 (1), 49-57, 2011 | 373 | 2011 |
| Nucleoside modifications in RNA limit activation of 2′-5′-oligoadenylate synthetase and increase resistance to cleavage by RNase L BR Anderson, H Muramatsu, BK Jha, RH Silverman, D Weissman, ... Nucleic acids research 39 (21), 9329-9338, 2011 | 363 | 2011 |
| Antagonism of the interferon-induced OAS-RNase L pathway by murine coronavirus ns2 protein is required for virus replication and liver pathology L Zhao, BK Jha, A Wu, R Elliott, J Ziebuhr, AE Gorbalenya, RH Silverman, ... Cell host & microbe 11 (6), 607-616, 2012 | 345 | 2012 |
| West Nile virus noncoding subgenomic RNA contributes to viral evasion of the type I interferon-mediated antiviral response A Schuessler, A Funk, HM Lazear, DA Cooper, S Torres, S Daffis, BK Jha, ... Journal of virology 86 (10), 5708-5718, 2012 | 215 | 2012 |
| Homologous 2′, 5′-phosphodiesterases from disparate RNA viruses antagonize antiviral innate immunity R Zhang, BK Jha, KM Ogden, B Dong, L Zhao, R Elliott, JT Patton, ... Proceedings of the National Academy of Sciences 110 (32), 13114-13119, 2013 | 140 | 2013 |
| Mode and specificity of binding of the small molecule GANT61 to GLI determines inhibition of GLI-DNA binding A Agyeman, BK Jha, T Mazumdar, JA Houghton Oncotarget 5 (12), 4492, 2014 | 138 | 2014 |
| Dimeric structure of pseudokinase RNase L bound to 2-5A reveals a basis for interferon-induced antiviral activity H Huang, E Zeqiraj, B Dong, BK Jha, NM Duffy, S Orlicky, ... Molecular cell 53 (2), 221-234, 2014 | 135 | 2014 |
| Small-molecule activators of RNase L with broad-spectrum antiviral activity CS Thakur, BK Jha, B Dong, J Das Gupta, KM Silverman, H Mao, H Sawai, ... Proceedings of the National Academy of Sciences 104 (23), 9585-9590, 2007 | 130 | 2007 |
| Middle East respiratory syndrome coronavirus NS4b protein inhibits host RNase L activation JM Thornbrough, BK Jha, B Yount, SA Goldstein, Y Li, R Elliott, AC Sims, ... MBio 7 (2), 10.1128/mbio. 00258-16, 2016 | 126 | 2016 |
| Leukemogenic nucleophosmin mutation disrupts the transcription factor hub that regulates granulomonocytic fates X Gu, Q Ebrahem, RZ Mahfouz, M Hasipek, F Enane, T Radivoyevitch, ... The Journal of clinical investigation 128 (10), 4260-4279, 2018 | 108 | 2018 |
| Novel protein disulfide isomerase inhibitor with anticancer activity in multiple myeloma S Vatolin, JG Phillips, BK Jha, S Govindgari, J Hu, D Grabowski, Y Parker, ... Cancer research 76 (11), 3340-3350, 2016 | 100 | 2016 |
| A phylogenetically conserved RNA structure in the poliovirus open reading frame inhibits the antiviral endoribonuclease RNase L JQ Han, HL Townsend, BK Jha, JM Paranjape, RH Silverman, DJ Barton Journal of virology 81 (11), 5561-5572, 2007 | 99 | 2007 |
| Inhibition of RNase L and RNA-dependent protein kinase (PKR) by sunitinib impairs antiviral innate immunity BK Jha, I Polyakova, P Kessler, B Dong, B Dickerman, GC Sen, ... Journal of Biological Chemistry 286 (30), 26319-26326, 2011 | 96 | 2011 |
| Suppression of antiviral innate immunity by sunitinib enhances oncolytic virotherapy BK Jha, B Dong, CT Nguyen, I Polyakova, RH Silverman Molecular Therapy 21 (9), 1749-1757, 2013 | 82 | 2013 |
| Evasion of antiviral innate immunity by Theiler's virus L* protein through direct inhibition of RNase L F Sorgeloos, BK Jha, RH Silverman, T Michiels PLoS pathogens 9 (6), e1003474, 2013 | 81 | 2013 |
| Hepatitis C virus RNA: dinucleotide frequencies and cleavage by RNase L CL Washenberger, JQ Han, KJ Kechris, BK Jha, RH Silverman, DJ Barton Virus research 130 (1-2), 85-95, 2007 | 76 | 2007 |
| Decitabine-and 5-azacytidine resistance emerges from adaptive responses of the pyrimidine metabolism network X Gu, R Tohme, B Tomlinson, N Sakre, M Hasipek, L Durkin, C Schuerger, ... Leukemia 35 (4), 1023-1036, 2021 | 68 | 2021 |
| Ribonuclease L and metal-ion–independent endoribonuclease cleavage sites in host and viral RNAs DA Cooper, BK Jha, RH Silverman, JR Hesselberth, DJ Barton Nucleic acids research 42 (8), 5202-5216, 2014 | 66 | 2014 |
| A viral RNA competitively inhibits the antiviral endoribonuclease domain of RNase L HL Townsend, BK Jha, JQ Han, NK Maluf, RH Silverman, DJ Barton Rna 14 (6), 1026-1036, 2008 | 65 | 2008 |
jarek maciejewskiVerified email at ccf.org
