Manuel Ascano
TitoloCitata daAnno
Transcriptome-wide identification of RNA-binding protein and microRNA target sites by PAR-CLIP
M Hafner, M Landthaler, L Burger, M Khorshid, J Hausser, P Berninger, ...
Cell 141 (1), 129-141, 2010
22592010
Integrative regulatory mapping indicates that the RNA-binding protein HuR couples pre-mRNA processing and mRNA stability
N Mukherjee, DL Corcoran, JD Nusbaum, DW Reid, S Georgiev, ...
Molecular cell 43 (3), 327-339, 2011
4852011
FMRP targets distinct mRNA sequence elements to regulate protein expression
M Ascano, N Mukherjee, P Bandaru, JB Miller, JD Nusbaum, DL Corcoran, ...
Nature 492 (7429), 382, 2012
4362012
Cyclic [G (2′, 5′) pA (3′, 5′) p] is the metazoan second messenger produced by DNA-activated cyclic GMP-AMP synthase
P Gao, M Ascano, Y Wu, W Barchet, BL Gaffney, T Zillinger, AA Serganov, ...
Cell 153 (5), 1094-1107, 2013
3992013
PAR-CliP-a method to identify transcriptome-wide the binding sites of RNA binding proteins
M Hafner, M Landthaler, L Burger, M Khorshid, J Hausser, P Berninger, ...
JoVE (Journal of Visualized Experiments), e2034, 2010
2602010
Structure-function analysis of STING activation by c [G (2′, 5′) pA (3′, 5′) p] and targeting by antiviral DMXAA
P Gao, M Ascano, T Zillinger, W Wang, P Dai, AA Serganov, BL Gaffney, ...
Cell 154 (4), 748-762, 2013
2362013
Identification of RNA–protein interaction networks using PAR‐CLIP
M Ascano, M Hafner, P Cekan, S Gerstberger, T Tuschl
Wiley Interdisciplinary Reviews: RNA 3 (2), 159-177, 2012
1892012
Identification of a functional interaction between the transmembrane protein Smoothened and the kinesin-related protein Costal2
SK Ogden, M Ascano Jr, MA Stegman, LM Suber, JE Hooper, DJ Robbins
Current biology 13 (22), 1998-2003, 2003
1332003
Regulation of Hedgehog signaling: a complex story
SK Ogden, M Ascano Jr, MA Stegman, DJ Robbins
Biochemical pharmacology 67 (5), 805-814, 2004
1182004
Multimeric assembly and biochemical characterization of the Trax–translin endonuclease complex
Y Tian, DK Simanshu, M Ascano, R Diaz-Avalos, AY Park, SA Juranek, ...
Nature structural & molecular biology 18 (6), 658, 2011
692011
PAR-CLIP (Photoactivatable Ribonucleoside-Enhanced Crosslinking and Immunoprecipitation): a step-by-step protocol to the transcriptome-wide identification of binding sites of…
J Spitzer, M Hafner, M Landthaler, M Ascano, T Farazi, G Wardle, ...
Methods in enzymology 539, 113-161, 2014
662014
Eukaryote-specific insertion elements control human ARGONAUTE slicer activity
K Nakanishi, M Ascano, T Gogakos, S Ishibe-Murakami, AA Serganov, ...
Cell reports 3 (6), 1893-1900, 2013
662013
Evolutionary conservation and expression of human RNA-binding proteins and their role in human genetic disease
S Gerstberger, M Hafner, M Ascano, T Tuschl
Systems biology of RNA binding proteins, 1-55, 2014
642014
Costal2 functions as a kinesin-like protein in the hedgehog signal transduction pathway
SF Farzan, M Ascano Jr, SK Ogden, M Sanial, A Brigui, A Plessis, ...
Current Biology 18 (16), 1215-1220, 2008
502008
Multi-disciplinary methods to define RNA–protein interactions and regulatory networks
M Ascano, S Gerstberger, T Tuschl
Current opinion in genetics & development 23 (1), 20-28, 2013
472013
The carboxyl-terminal domain of the protein kinase fused can function as a dominant inhibitor of hedgehog signaling
M Ascano, KE Nybakken, J Sosinski, MA Stegman, DJ Robbins
Molecular and cellular biology 22 (5), 1555-1566, 2002
472002
The full-length unprocessed hedgehog protein is an active signaling molecule
R Tokhunts, S Singh, T Chu, G d'Angelo, V Baubet, JA Goetz, Z Huang, ...
Journal of Biological Chemistry 285 (4), 2562-2568, 2010
442010
Small molecule inhibition of cGAS reduces interferon expression in primary macrophages from autoimmune mice
J Vincent, C Adura, P Gao, A Luz, L Lama, Y Asano, R Okamoto, ...
Nature communications 8 (1), 750, 2017
402017
The Kinesin-related protein Costal2 associates with membranes in a Hedgehog-sensitive, Smoothened-independent manner
MA Stegman, JA Goetz, M Ascano, SK Ogden, KE Nybakken, DJ Robbins
Journal of Biological Chemistry 279 (8), 7064-7071, 2004
382004
Binding-pocket and lid-region substitutions render human STING sensitive to the species-specific drug DMXAA
P Gao, T Zillinger, W Wang, M Ascano, P Dai, G Hartmann, T Tuschl, ...
Cell reports 8 (6), 1668-1676, 2014
362014
Il sistema al momento non pu eseguire l'operazione. Riprova pi tardi.
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