| Structure of the nociceptin/orphanin FQ receptor in complex with a peptide mimetic AA Thompson, W Liu, E Chun, V Katritch, H Wu, E Vardy, XP Huang, ... Nature 485 (7398), 395-399, 2012 | 590 | 2012 |
| Recent advances in the stereoselective synthesis of trans-3,4-disubstituted-piperidines: applications to (−)-paroxetine C De Risi, G Fanton, GP Pollini, C Trapella, F Valente, V Zanirato Tetrahedron: Asymmetry 19 (2), 131-155, 2008 | 110 | 2008 |
| Structure-activity studies on neuropeptide S: identification of the amino acid residues crucial for receptor activation AL Roth, E Marzola, A Rizzi, M Arduin, C Trapella, C Corti, R Vergura, ... Journal of biological chemistry 281 (30), 20809-20816, 2006 | 110 | 2006 |
| Anxiolytic-and antidepressant-like activities of H-Dmt-Tic-NH-CH (CH2-COOH)-Bid (UFP-512), a novel selective delta opioid receptor agonist R Vergura, G Balboni, B Spagnolo, E Gavioli, DG Lambert, J McDonald, ... Peptides 29 (1), 93-103, 2008 | 106 | 2008 |
| Novel halogenated derivates of JWH-018: behavioral and binding studies in mice A Vigolo, A Ossato, C Trapella, F Vincenzi, C Rimondo, C Seri, K Varani, ... Neuropharmacology 95, 68-82, 2015 | 91 | 2015 |
| Pharmacological characterization of the nociceptin/orphanin FQ receptor antagonist SB-612111 [(–)-cis-1-methyl-7-[[4-(2, 6-dichlorophenyl) piperidin-1-yl] methyl]-6, 7, 8, 9 … A Rizzi, EC Gavioli, G Marzola, B Spagnolo, S Zucchini, R Ciccocioppo, ... Journal of Pharmacology and Experimental Therapeutics 321 (3), 968-974, 2007 | 91 | 2007 |
| The nociceptin/orphanin FQ receptor antagonist J-113397 and L-DOPA additively attenuate experimental parkinsonism through overinhibition of the nigrothalamic pathway M Marti, C Trapella, R Viaro, M Morari Journal of Neuroscience 27 (6), 1297-1307, 2007 | 91 | 2007 |
| The importance of ligand-receptor conformational pairs in stabilization: spotlight on the N/OFQ G protein-coupled receptor RL Miller, AA Thompson, C Trapella, R Guerrini, D Malfacini, N Patel, ... Structure 23 (12), 2291-2299, 2015 | 86 | 2015 |
| HelixComplex snail mucus exhibits pro-survival, proliferative and pro-migration effects on mammalian fibroblasts C Trapella, R Rizzo, S Gallo, A Alogna, D Bortolotti, F Casciano, G Zauli, ... Scientific reports 8 (1), 17665, 2018 | 85 | 2018 |
| Effect of the novel synthetic cannabinoids AKB48 and 5F-AKB48 on “tetrad”, sensorimotor, neurological and neurochemical responses in mice. In vitro and in vivo pharmacological … I Canazza, A Ossato, C Trapella, A Fantinati, MA De Luca, G Margiani, ... Psychopharmacology 233, 3685-3709, 2016 | 81 | 2016 |
| Effect of JWH-250, JWH-073 and their interaction on “tetrad”, sensorimotor, neurological and neurochemical responses in mice A Ossato, I Canazza, C Trapella, F Vincenzi, MA De Luca, C Rimondo, ... Progress in Neuro-Psychopharmacology and Biological Psychiatry 67, 31-50, 2016 | 77 | 2016 |
| Triazine compounds as antagonists at Bv8-prokineticin receptors G Balboni, I Lazzari, C Trapella, L Negri, R Lattanzi, E Giannini, A Nicotra, ... Journal of medicinal chemistry 51 (23), 7635-7639, 2008 | 75 | 2008 |
| Pharmacological profile of NOP receptors coupled with calcium signaling via the chimeric protein Gαqi5 V Camarda, C Fischetti, N Anzellotti, P Molinari, C Ambrosio, E Kostenis, ... Naunyn-Schmiedeberg's archives of pharmacology 379, 599-607, 2009 | 74 | 2009 |
| Pharmacological Characterization of the Nociceptin/Orphanin FQ Receptor Antagonist SB-612111 [(–)-cis-1-Methyl-7-[[4-(2, 6-dichlorophenyl) piperidin-1-yl] methyl]-6, 7, 8, 9 … B Spagnolo, G Carrà, M Fantin, C Fischetti, C Hebbes, J McDonald, ... Journal of Pharmacology and Experimental Therapeutics 321 (3), 961-967, 2007 | 74 | 2007 |
| Endogenous nociceptin/orphanin FQ signalling produces opposite spinal antinociceptive and supraspinal pronociceptive effects in the mouse formalin test: pharmacological and … A Rizzi, C Nazzaro, GG Marzola, S Zucchini, C Trapella, R Guerrini, ... Pain 124 (1-2), 100-108, 2006 | 73 | 2006 |
| JWH-018 impairs sensorimotor functions in mice A Ossato, A Vigolo, C Trapella, C Seri, C Rimondo, G Serpelloni, M Marti Neuroscience 300, 174-188, 2015 | 71 | 2015 |
| Nociceptin/orphanin FQ receptor blockade attenuates MPTP-induced parkinsonism R Viaro, R Sanchez-Pernaute, M Marti, C Trapella, O Isacson, M Morari Neurobiology of disease 30 (3), 430-438, 2008 | 70 | 2008 |
| Synthesis and biological activity of nociceptin/orphanin FQ analogues substituted in position 7 or 11 with Cα, α-dialkylated amino acids M Arduin, B Spagnolo, G Calò, R Guerrini, G Carrà, C Fischetti, C Trapella, ... Bioorganic & medicinal chemistry 15 (13), 4434-4443, 2007 | 68 | 2007 |
| Synthesis and biological activity of human neuropeptide S analogues modified in position 5: identification of potent and pure neuropeptide S receptor antagonists R Guerrini, V Camarda, C Trapella, G Calò, A Rizzi, C Ruzza, S Fiorini, ... Journal of medicinal chemistry 52 (2), 524-529, 2009 | 63 | 2009 |
| Further studies on the pharmacological profile of the neuropeptide S receptor antagonist SHA 68 C Ruzza, A Rizzi, C Trapella, V Camarda, V Ruggieri, M Filaferro, C Cifani, ... Peptides 31 (5), 915-925, 2010 | 62 | 2010 |
