Paulette Greenidge FRSC
Paulette Greenidge FRSC
Principal Computational Chemist
Email verificata su sprintbioscience.com - Home page
TitoloCitata daAnno
Antimalarial activity: the search for marine-derived natural products with selective antimalarial activity
AD Wright, GM Knig, CK Angerhofer, P Greenidge, A Linden, ...
Journal of Natural Products 59 (7), 710-716, 1996
1691996
MM/GBSA binding energy prediction on the PDBbind data set: successes, failures, and directions for further improvement
PA Greenidge, C Kramer, JC Mozziconacci, RM Wolf
Journal of chemical information and modeling 53 (1), 201-209, 2012
1392012
Evaluation of machine-learning methods for ligand-based virtual screening
B Chen, RF Harrison, G Papadatos, P Willett, DJ Wood, XQ Lewell, ...
Journal of computer-aided molecular design 21 (1-3), 53-62, 2007
1162007
Pseudoreceptor modeling: The construction of three-dimensional receptor surrogates
A Vedani, P Zbinden, JP Snyder, PA Greenidge
Journal of the American Chemical Society 117 (17), 4987-4994, 1995
1121995
Pharmacophores incorporating numerous excluded volumes defined by X-ray crystallographic structure in three-dimensional database searching: application to the thyroid hormone…
PA Greenidge, B Carlsson, LG Bladh, M Gillner
Journal of medicinal chemistry 41 (14), 2503-2512, 1998
751998
Improving docking results via reranking of ensembles of ligand poses in multiple X-ray protein conformations with MM-GBSA
PA Greenidge, C Kramer, JC Mozziconacci, W Sherman
Journal of chemical information and modeling 54 (10), 2697-2717, 2014
462014
Discovery of novel indolinone-based, potent, selective and brain penetrant inhibitors of LRRK2
T Troxler, P Greenidge, K Zimmermann, S Desrayaud, P Drueckes, ...
Bioorganic & medicinal chemistry letters 23 (14), 4085-4090, 2013
362013
Functional Probing of the Human Glucocorticoid Receptor Steroid-interacting Surface by Site-directed Mutagenesis Gln-642 PLAYS AN IMPORTANT ROLE IN STEROID RECOGNITION AND BINDING
U Lind, P Greenidge, M Gillner, KF Koehler, A Wright, J Carlstedt-Duke
Journal of Biological Chemistry 275 (25), 19041-19049, 2000
342000
Structure–activity relationships of cannabinoids: A joint CoMFA and pseudoreceptor modelling study
S Schmetzer, P Greenidge, KA Kovar, M Schulze-Alexandru, G Folkers
Journal of computer-aided molecular design 11 (3), 278-292, 1997
311997
DNA minor groove recognition properties of pentamidine and its analogs: a molecular modeling study.
PA Greenidge, TC Jenkins, S Neidle
Molecular pharmacology 43 (6), 982-988, 1993
301993
Generation of ligand conformations in continuum solvent consistent with protein active site topology: Application to thrombin
PA Greenidge, SAM Mrette, R Beck, G Dodson, CA Goodwin, MF Scully, ...
Journal of medicinal chemistry 46 (8), 1293-1305, 2003
272003
Valine 571 functions as a regional organizer in programming the glucocorticoid receptor for differential binding of glucocorticoids and mineralocorticoids
U Lind, P Greenidge, J Gustafsson, APH Wright, J Carlstedt-Duke
Journal of Biological Chemistry 274 (26), 18515-18523, 1999
251999
Introducing the consensus modeling concept in genetic algorithms: application to interpretable discriminant analysis
M Ganguly, N Brown, A Schuffenhauer, P Ertl, VJ Gillet, PA Greenidge
Journal of chemical information and modeling 46 (5), 2110-2124, 2006
232006
A Comparison of Methods for Pharmacophore Generation with the Catalyst Software and their Use for 3D-QSAR Application to a Set of 4-Aminopyridine Thrombin Inhibitors
PA Greenidge, J Weiser
Mini reviews in medicinal chemistry 1 (1), 79-87, 2001
222001
The use of multiple excluded volumes derived from X-ray crystallographic structures in 3D database searching and 3D QSAR
M Gillner, P Greenidge
Pharmacophore Perception, Development and Use in Drug Design, 372-384, 2000
82000
Factors involved in guanine/cytosine (G/C) selectivity of DNA-binding drugs: a molecular modelling study of ligand interactions with a tyr T DNA sequence
PA Greenidge, CA Laughton, TC Jenkins, S Neidle
Journal of the Chemical Society, Faraday Transactions 89 (15), 2651-2657, 1993
71993
A pseudoreceptor modelling study of the varicella-zoster virus and human thymidine kinase binding sites
PA Greenidge, A Merz, G Folkers
Journal of computer-aided molecular design 9 (6), 473-478, 1995
41995
Boosting Pose Ranking Performance via Rescoring with MM‐GBSA
PA Greenidge, RA Lewis, P Ertl
Chemical biology & drug design 88 (3), 317-328, 2016
32016
The modelling of β2-adrenergic receptors
PA Greenidge
Pharmaceutica Acta Helvetiae 68 (4), 201-210, 1994
31994
Serine protease inhibitors compromising a hydrogen-bond acceptor
J Deadman, J Spencer, P Greenidge, C Goodwin, V Kakkar, M Scully, ...
US Patent App. 10/466,736, 2004
22004
Il sistema al momento non pu eseguire l'operazione. Riprova pi tardi.
Articoli 1–20