Cellular senescence is induced by the environmental neurotoxin paraquat and contributes to neuropathology linked to Parkinson’s disease SJ Chinta, G Woods, M Demaria, A Rane, Y Zou, A McQuade, ... Cell reports 22 (4), 930-940, 2018 | 402 | 2018 |
Development and validation of a simplified method to generate human microglia from pluripotent stem cells A McQuade, M Coburn, CH Tu, J Hasselmann, H Davtyan, ... Molecular neurodegeneration 13, 1-13, 2018 | 281 | 2018 |
Development of a chimeric model to study and manipulate human microglia in vivo J Hasselmann, MA Coburn, W England, DXF Velez, SK Shabestari, ... Neuron 103 (6), 1016-1033. e10, 2019 | 246 | 2019 |
Gene expression and functional deficits underlie TREM2-knockout microglia responses in human models of Alzheimer’s disease A McQuade, YJ Kang, J Hasselmann, A Jairaman, A Sotelo, M Coburn, ... Nature communications 11 (1), 5370, 2020 | 197 | 2020 |
Microglia in Alzheimer's disease: exploring how genetics and phenotype influence risk A McQuade, M Blurton-Jones Journal of molecular biology 431 (9), 1805-1817, 2019 | 178 | 2019 |
Absence of microglia promotes diverse pathologies and early lethality in Alzheimer’s disease mice SK Shabestari, S Morabito, EP Danhash, A McQuade, JR Sanchez, ... Cell reports 39 (11), 2022 | 58 | 2022 |
Human neural cell type‐specific extracellular vesicle proteome defines disease‐related molecules associated with activated astrocytes in Alzheimer's disease brain Y You, S Muraoka, MP Jedrychowski, J Hu, AK McQuade, ... Journal of extracellular vesicles 11 (1), e12183, 2022 | 58 | 2022 |
Multi-omic comparison of Alzheimer’s variants in human ESC–derived microglia reveals convergence at APOE T Liu, B Zhu, Y Liu, X Zhang, J Yin, X Li, LL Jiang, AP Hodges, ... Journal of Experimental Medicine 217 (12), e20200474, 2020 | 41 | 2020 |
TREM2 regulates purinergic receptor-mediated calcium signaling and motility in human iPSC-derived microglia A Jairaman, A McQuade, A Granzotto, YJ Kang, JP Chadarevian, ... Elife 11, e73021, 2022 | 31 | 2022 |
Amyloid-beta impairs TOM1-mediated IL-1R1 signaling A Cadete Martini, A Gomez-Arboledas, S Forner, CJ Rodriguez-Ortiz, ... Proceedings of the National Academy of Sciences 116 (42), 21198-21206, 2019 | 23 | 2019 |
Cellular senescence is induced by the environmental neurotoxin paraquat and contributes to neuropathology linked to Parkinson’s disease. Cell Rep 22: 930–940 SJ Chinta, G Woods, M Demaria, A Rane, Y Zou, A McQuade, ... | 15 | 2018 |
Cellular senescence is induced by the environmental neurotoxin paraquat and contributes to neuropathology linked to parkinson’s disease. Cell Rep. 2018; 22: 930–40 SJ Chinta, G Woods, M Demaria, A Rane, Y Zou, A McQuade, ... CAS PubMed PubMed Central, 930, 2015 | 11 | 2015 |
Moderate intrinsic phenotypic alterations in C9orf72 ALS/FTD iPSC-microglia despite the presence of C9orf72 pathological features I Lorenzini, E Alsop, J Levy, LM Gittings, D Lall, BE Rabichow, S Moore, ... Frontiers in cellular neuroscience 17, 1179796, 2023 | 8 | 2023 |
Human induced pluripotent stem cell-derived microglia (hiPSC-microglia) A McQuade, M Blurton-Jones Induced Pluripotent Stem (iPS) Cells: Methods and Protocols, 473-482, 2021 | 8 | 2021 |
Activated iPSC-microglia from C9orf72 ALS/FTD patients exhibit endosomal-lysosomal dysfunction I Lorenzini, E Alsop, J Levy, LM Gittings, BE Rabichow, D Lall, S Moore, ... BioRxiv, 2020.09. 03.277459, 2020 | 8 | 2020 |
Author Correction: Gene expression and functional deficits underlie TREM2-knockout microglia responses in human models of Alzheimer’s disease A McQuade, YJ Kang, J Hasselmann, A Jairaman, A Sotelo, M Coburn, ... nature communications 14, 2023 | 4 | 2023 |
Alteration of microglial metabolism and inflammatory profile contributes to neurotoxicity in a hiPSC-derived microglia model of frontotemporal dementia 3 H Haukedal, SS Lorenzen, EW Westi, GI Corsi, VP Gadekar, A McQuade, ... Brain, Behavior, and Immunity 113, 353-373, 2023 | 1 | 2023 |
Genetic contribution to microglial activation in schizophrenia M Koskuvi, E Pörsti, T Hewitt, N Räsänen, YC Wu, K Trontti, A McQuade, ... Molecular Psychiatry, 1-12, 2024 | | 2024 |
Neurotoxic Microglial Activation via IFNγ‐Induced Nrf2 Reduction Exacerbating Alzheimer's Disease YJ Kang, SJ Hyeon, A McQuade, J Lim, SH Baek, YN Diep, KV Do, ... Advanced Science, 2304357, 2024 | | 2024 |
ER and SOCE Ca2+ signals are not required for directed cell migration in human microglia A Granzotto, A McQuade, JP Chadarevian, H Davtyan, SL Sensi, I Parker, ... bioRxiv, 2024.01. 18.576126, 2024 | | 2024 |