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Amanda McQuade
Amanda McQuade
Email verificata su uci.edu
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Citata da
Citata da
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Cellular senescence is induced by the environmental neurotoxin paraquat and contributes to neuropathology linked to Parkinson’s disease
SJ Chinta, G Woods, M Demaria, A Rane, Y Zou, A McQuade, ...
Cell reports 22 (4), 930-940, 2018
4022018
Development and validation of a simplified method to generate human microglia from pluripotent stem cells
A McQuade, M Coburn, CH Tu, J Hasselmann, H Davtyan, ...
Molecular neurodegeneration 13, 1-13, 2018
2812018
Development of a chimeric model to study and manipulate human microglia in vivo
J Hasselmann, MA Coburn, W England, DXF Velez, SK Shabestari, ...
Neuron 103 (6), 1016-1033. e10, 2019
2462019
Gene expression and functional deficits underlie TREM2-knockout microglia responses in human models of Alzheimer’s disease
A McQuade, YJ Kang, J Hasselmann, A Jairaman, A Sotelo, M Coburn, ...
Nature communications 11 (1), 5370, 2020
1972020
Microglia in Alzheimer's disease: exploring how genetics and phenotype influence risk
A McQuade, M Blurton-Jones
Journal of molecular biology 431 (9), 1805-1817, 2019
1782019
Absence of microglia promotes diverse pathologies and early lethality in Alzheimer’s disease mice
SK Shabestari, S Morabito, EP Danhash, A McQuade, JR Sanchez, ...
Cell reports 39 (11), 2022
582022
Human neural cell type‐specific extracellular vesicle proteome defines disease‐related molecules associated with activated astrocytes in Alzheimer's disease brain
Y You, S Muraoka, MP Jedrychowski, J Hu, AK McQuade, ...
Journal of extracellular vesicles 11 (1), e12183, 2022
582022
Multi-omic comparison of Alzheimer’s variants in human ESC–derived microglia reveals convergence at APOE
T Liu, B Zhu, Y Liu, X Zhang, J Yin, X Li, LL Jiang, AP Hodges, ...
Journal of Experimental Medicine 217 (12), e20200474, 2020
412020
TREM2 regulates purinergic receptor-mediated calcium signaling and motility in human iPSC-derived microglia
A Jairaman, A McQuade, A Granzotto, YJ Kang, JP Chadarevian, ...
Elife 11, e73021, 2022
312022
Amyloid-beta impairs TOM1-mediated IL-1R1 signaling
A Cadete Martini, A Gomez-Arboledas, S Forner, CJ Rodriguez-Ortiz, ...
Proceedings of the National Academy of Sciences 116 (42), 21198-21206, 2019
232019
Cellular senescence is induced by the environmental neurotoxin paraquat and contributes to neuropathology linked to Parkinson’s disease. Cell Rep 22: 930–940
SJ Chinta, G Woods, M Demaria, A Rane, Y Zou, A McQuade, ...
152018
Cellular senescence is induced by the environmental neurotoxin paraquat and contributes to neuropathology linked to parkinson’s disease. Cell Rep. 2018; 22: 930–40
SJ Chinta, G Woods, M Demaria, A Rane, Y Zou, A McQuade, ...
CAS PubMed PubMed Central, 930, 2015
112015
Moderate intrinsic phenotypic alterations in C9orf72 ALS/FTD iPSC-microglia despite the presence of C9orf72 pathological features
I Lorenzini, E Alsop, J Levy, LM Gittings, D Lall, BE Rabichow, S Moore, ...
Frontiers in cellular neuroscience 17, 1179796, 2023
82023
Human induced pluripotent stem cell-derived microglia (hiPSC-microglia)
A McQuade, M Blurton-Jones
Induced Pluripotent Stem (iPS) Cells: Methods and Protocols, 473-482, 2021
82021
Activated iPSC-microglia from C9orf72 ALS/FTD patients exhibit endosomal-lysosomal dysfunction
I Lorenzini, E Alsop, J Levy, LM Gittings, BE Rabichow, D Lall, S Moore, ...
BioRxiv, 2020.09. 03.277459, 2020
82020
Author Correction: Gene expression and functional deficits underlie TREM2-knockout microglia responses in human models of Alzheimer’s disease
A McQuade, YJ Kang, J Hasselmann, A Jairaman, A Sotelo, M Coburn, ...
nature communications 14, 2023
42023
Alteration of microglial metabolism and inflammatory profile contributes to neurotoxicity in a hiPSC-derived microglia model of frontotemporal dementia 3
H Haukedal, SS Lorenzen, EW Westi, GI Corsi, VP Gadekar, A McQuade, ...
Brain, Behavior, and Immunity 113, 353-373, 2023
12023
Genetic contribution to microglial activation in schizophrenia
M Koskuvi, E Pörsti, T Hewitt, N Räsänen, YC Wu, K Trontti, A McQuade, ...
Molecular Psychiatry, 1-12, 2024
2024
Neurotoxic Microglial Activation via IFNγ‐Induced Nrf2 Reduction Exacerbating Alzheimer's Disease
YJ Kang, SJ Hyeon, A McQuade, J Lim, SH Baek, YN Diep, KV Do, ...
Advanced Science, 2304357, 2024
2024
ER and SOCE Ca2+ signals are not required for directed cell migration in human microglia
A Granzotto, A McQuade, JP Chadarevian, H Davtyan, SL Sensi, I Parker, ...
bioRxiv, 2024.01. 18.576126, 2024
2024
Il sistema al momento non può eseguire l'operazione. Riprova più tardi.
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