Yuan Wang
Yuan Wang
UCB Biosciences, Bedford, MA, USA
Verified email at ucb.com
Title
Cited by
Cited by
Year
Using information from historical high-throughput screens to predict active compounds
S Riniker, Y Wang, JL Jenkins, GA Landrum
Journal of chemical information and modeling 54 (7), 1880-1891, 2014
562014
Size uniformity of animal cells is actively maintained by a p38 MAPK-dependent regulation of G1-length
S Liu, MB Ginzberg, N Patel, M Hild, B Leung, Z Li, YC Chen, N Chang, ...
eLife 7, e26947, 2018
402018
Evidence-based and quantitative prioritization of tool compounds in phenotypic drug discovery
Y Wang, A Cornett, FJ King, Y Mao, F Nigsch, CG Paris, G McAllister, ...
Cell chemical biology 23 (7), 862-874, 2016
382016
Balancing the influence of molecular complexity on fingerprint similarity searching
Y Wang, J Bajorath
Journal of chemical information and modeling 48 (1), 75-84, 2008
312008
Apparent asymmetry in fingerprint similarity searching is a direct consequence of differences in bit densities and molecular size
Y Wang, H Eckert, J Bajorath
ChemMedChem 2 (7), 1037-1042, 2007
282007
Cheminformatics Tools for Analyzing and Designing Optimized Small-Molecule Collections and Libraries
N Moret, NA Clark, M Hafner, Y Wang, E Lounkine, M Medvedovic, ...
Cell chemical biology 26 (5), 765-777. e3, 2019
272019
Cheminformatics tools for analyzing and designing optimized Small-Molecule collections and libraries
N Moret, NA Clark, M Hafner, Y Wang, E Lounkine, M Medvedovic, ...
Cell chemical biology 26 (5), 765-777. e3, 2019
272019
Bit silencing in fingerprints enables the derivation of compound class-directed similarity metrics
Y Wang, J Bajorath
Journal of chemical information and modeling 48 (9), 1754-1759, 2008
262008
Advanced fingerprint methods for similarity searching: balancing molecular complexity effects
Y Wang, J Bajorath
Combinatorial chemistry & high throughput screening 13 (3), 220-228, 2010
192010
Shannon entropy-based fingerprint similarity search strategy
Y Wang, H Geppert, J Bajorath
Journal of chemical information and modeling 49 (7), 1687-1691, 2009
182009
Protein kinase A activation inhibits DUX4 gene expression in myotubes from patients with facioscapulohumeral muscular dystrophy
JM Cruz, N Hupper, LS Wilson, JB Concannon, Y Wang, B Oberhauser, ...
Journal of Biological Chemistry 293 (30), 11837-11849, 2018
172018
Development of a compound class-directed similarity coefficient that accounts for molecular complexity effects in fingerprint searching
Y Wang, J Bajorath
Journal of chemical information and modeling 49 (6), 1369-1376, 2009
172009
CPSF3-dependent pre-mRNA processing as a druggable node in AML and Ewing’s sarcoma
NT Ross, F Lohmann, S Carbonneau, A Fazal, WA Weihofen, S Gleim, ...
Nature Chemical Biology 16 (1), 50-59, 2020
162020
Systematic chemogenetic library assembly
SM Canham, Y Wang, A Cornett, DS Auld, DK Baeschlin, M Patoor, ...
Cell Chemical Biology, 2020
142020
A High Content Screen in Macrophages Identifies Small Molecule Modulators of STING-IRF3 and NFkB Signaling
PD Koch, HR Miller, G Yu, JA Tallarico, PK Sorger, Y Wang, Y Feng, ...
ACS chemical biology 13 (4), 1066-1081, 2018
122018
Random reduction in fingerprint bit density improves compound recall in search calculations using complex reference molecules
Y Wang, H Geppert, J Bajorath
Chemical biology & drug design 71 (6), 511-517, 2008
122008
Quantitative Prioritization of Tool Compounds for Phenotypic Screening
Y Wang, JL Jenkins
Phenotypic Screening, 195-206, 2018
32018
Mining gene-centric relationships from literature: the roles of gene mutation and gene expression in supporting drug discovery
L Tari, J Patel, J Küntzer, Y Li, Z Peng, Y Wang, L Aguiar, J Cai
International journal of data mining and bioinformatics 10 (4), 357-373, 2014
32014
A novel Descriptor histogram filtering method for database mining and the identification of active molecules
Y Wang, JW Godden, J Bajorath
Letters in Drug Design & Discovery 4 (4), 286-292, 2007
22007
Mining gene-centric relationships from literature to support drug discovery
L Tari, J Kuntzer, J Patel, Y Li, Z Peng, Y Wang, L Aguiar, J Cai
2011 IEEE International Conference on Bioinformatics and Biomedicine, 639-644, 2011
12011
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Articles 1–20