Differential expression of immune-regulatory genes associated with PD-L1 display in melanoma: implications for PD-1 pathway blockade JM Taube, GD Young, TL McMiller, S Chen, JT Salas, TS Pritchard, H Xu, ... Clinical Cancer Research 21 (17), 3969-3976, 2015 | 178 | 2015 |
MiR-9,-31, and-182 deregulation promote proliferation and tumor cell survival in colon cancer L Cekaite, JK Rantala, J Bruun, M Guriby, TH Ågesen, SA Danielsen, ... Neoplasia 14 (9), 868-IN21, 2012 | 142 | 2012 |
Multi-omics of 34 colorectal cancer cell lines-a resource for biomedical studies KCG Berg, PW Eide, IA Eilertsen, B Johannessen, J Bruun, SA Danielsen, ... Molecular cancer 16 (1), 1-16, 2017 | 109 | 2017 |
Connexin43 acts as a colorectal cancer tumor suppressor and predicts disease outcome S Sirnes, J Bruun, M Kolberg, A Kjenseth, GE Lind, A Svindland, A Brech, ... International journal of cancer 131 (3), 570-581, 2012 | 106 | 2012 |
Colorectal cancer consensus molecular subtypes translated to preclinical models uncover potentially targetable cancer cell dependencies A Sveen, J Bruun, PW Eide, IA Eilertsen, L Ramirez, A Murumägi, ... Clinical Cancer Research 24 (4), 794-806, 2018 | 93 | 2018 |
Prognostic significance of β-catenin, E-cadherin, and SOX9 in colorectal cancer: results from a large population-representative series J Bruun, M Kolberg, JM Nesland, A Svindland, A Nesbakken, RA Lothe Frontiers in oncology 4, 118, 2014 | 66 | 2014 |
The gap junction channel protein connexin 43 is covalently modified and regulated by SUMOylation A Kjenseth, TA Fykerud, S Sirnes, J Bruun, Z Yohannes, M Kolberg, ... Journal of Biological Chemistry 287 (19), 15851-15861, 2012 | 64 | 2012 |
Multispectral imaging for quantitative and compartment‐specific immune infiltrates reveals distinct immune profiles that classify lung cancer patients A Mezheyeuski, CH Bergsland, M Backman, D Djureinovic, T Sjöblom, ... The Journal of pathology 244 (4), 421-431, 2018 | 59 | 2018 |
NEDD4 is overexpressed in colorectal cancer and promotes colonic cell growth independently of the PI3K/PTEN/AKT pathway PW Eide, L Cekaite, SA Danielsen, IA Eilertsen, A Kjenseth, TA Fykerud, ... Cellular signalling 25 (1), 12-18, 2013 | 55 | 2013 |
Cancer stemness, intratumoral heterogeneity, and immune response across cancers A Miranda, PT Hamilton, AW Zhang, S Pattnaik, E Becht, A Mezheyeuski, ... Proceedings of the National Academy of Sciences 116 (18), 9020-9029, 2019 | 53 | 2019 |
CMScaller: an R package for consensus molecular subtyping of colorectal cancer pre-clinical models PW Eide, J Bruun, RA Lothe, A Sveen Scientific reports 7 (1), 1-8, 2017 | 53 | 2017 |
Smad ubiquitination regulatory factor-2 controls gap junction intercellular communication by modulating endocytosis and degradation of connexin43 TA Fykerud, A Kjenseth, KO Schink, S Sirnes, J Bruun, Y Omori, A Brech, ... Journal of cell science 125 (17), 3966-3976, 2012 | 41 | 2012 |
Connexins in colorectal cancer pathogenesis S Sirnes, GE Lind, J Bruun, TA Fykerud, M Mesnil, RA Lothe, E Rivedal, ... International journal of cancer 137 (1), 1-11, 2015 | 34 | 2015 |
40^ sup th^ EASD Annual Meeting of the European Association for the Study of Diabetes M Veitenhansl, K Stegner, FX Hierl, C Dieterle, H Feldmeier, B Gutt, ... Diabetologia 47, A1, 2004 | 33 | 2004 |
Combination therapies with HSP90 inhibitors against colorectal cancer K Kryeziu, J Bruun, TK Guren, A Sveen, RA Lothe Biochimica et Biophysica Acta (BBA)-Reviews on Cancer 1871 (2), 240-247, 2019 | 27 | 2019 |
Regulator of chromosome condensation 2 identifies high-risk patients within both major phenotypes of colorectal cancer J Bruun, M Kolberg, TC Ahlquist, EC Røyrvik, T Nome, E Leithe, GE Lind, ... Clinical cancer research 21 (16), 3759-3770, 2015 | 27 | 2015 |
Inhibition of connexin43 gap junction channels by the endocrine disruptor ioxynil E Leithe, A Kjenseth, J Bruun, S Sirnes, E Rivedal Toxicology and applied pharmacology 247 (1), 10-17, 2010 | 25 | 2010 |
Common fusion transcripts identified in colorectal cancer cell lines by high-throughput RNA sequencing T Nome, GOS Thomassen, J Bruun, T Ahlquist, AC Bakken, AM Hoff, ... Translational oncology 6 (5), 546-IN5, 2013 | 22 | 2013 |
Prognostic, predictive, and pharmacogenomic assessments of CDX 2 refine stratification of colorectal cancer J Bruun, A Sveen, R Barros, PW Eide, I Eilertsen, M Kolberg, T Pellinen, ... Molecular oncology 12 (9), 1639-1655, 2018 | 21 | 2018 |
Identification of novel fusion genes in testicular germ cell tumors AM Hoff, S Alagaratnam, S Zhao, J Bruun, PW Andrews, RA Lothe, ... Cancer research 76 (1), 108-116, 2016 | 15 | 2016 |