| Carbonic anhydrase inhibitors targeting metabolism and tumor microenvironment A Angeli, F Carta, A Nocentini, JY Winum, R Zalubovskis, A Akdemir, ... Metabolites 10 (10), 412, 2020 | 124 | 2020 |
| Use of acetylcholine binding protein in the search for novel α7 nicotinic receptor ligands. In silico docking, pharmacological screening, and X-ray analysis C Ulens, A Akdemir, A Jongejan, R Van Elk, S Bertrand, A Perrakis, ... Journal of medicinal chemistry 52 (8), 2372-2383, 2009 | 112 | 2009 |
| Xanthates and trithiocarbonates strongly inhibit carbonic anhydrases and show antiglaucoma effects in vivo F Carta, A Akdemir, A Scozzafava, E Masini, CT Supuran Journal of medicinal chemistry 56 (11), 4691-4700, 2013 | 111 | 2013 |
| Fragment growing induces conformational changes in acetylcholine-binding protein: a structural and thermodynamic analysis E Edink, P Rucktooa, K Retra, A Akdemir, T Nahar, O Zuiderveld, ... Journal of the American Chemical Society 133 (14), 5363-5371, 2011 | 108 | 2011 |
| Synthesis of coumarin-sulfonamide derivatives and determination of their cytotoxicity, carbonic anhydrase inhibitory and molecular docking studies BZ Kurt, F Sonmez, D Ozturk, A Akdemir, A Angeli, CT Supuran European Journal of Medicinal Chemistry 183, 111702, 2019 | 70 | 2019 |
| A novel library of saccharin and acesulfame derivatives as potent and selective inhibitors of carbonic anhydrase IX and XII isoforms S Carradori, D Secci, C De Monte, A Mollica, M Ceruso, A Akdemir, ... Bioorganic & Medicinal Chemistry 24 (5), 1095-1105, 2016 | 67 | 2016 |
| A Class of Sulfonamides with Strong Inhibitory Action against the α-Carbonic Anhydrase from Trypanosoma cruzi O Guzel-Akdemir, A Akdemir, P Pan, AB Vermelho, S Parkkila, ... Journal of Medicinal Chemistry 56 (14), 5773-5781, 2013 | 65 | 2013 |
| Anti-Candida activity and cytotoxicity of a large library of new N-substituted-1, 3-thiazolidin-4-one derivatives C De Monte, S Carradori, B Bizzarri, A Bolasco, F Caprara, A Mollica, ... European Journal of Medicinal Chemistry 107, 82-96, 2016 | 61 | 2016 |
| The extremo-α-carbonic anhydrase (CA) from Sulfurihydrogenibium azorense, the fastest CA known, is highly activated by amino acids and amines A Akdemir, D Vullo, V De Luca, A Scozzafava, V Carginale, M Rossi, ... Bioorganic & medicinal chemistry letters 23 (4), 1087-1090, 2013 | 59 | 2013 |
| Discovery of novel isatin-based sulfonamides with potent and selective inhibition of the tumor-associated carbonic anhydrase isoforms IX and XII Ö Güzel-Akdemir, A Akdemir, N Karalı, CT Supuran Organic & biomolecular chemistry 13 (23), 6493-6499, 2015 | 58 | 2015 |
| Open saccharin-based secondary sulfonamides as potent and selective inhibitors of cancer-related carbonic anhydrase IX and XII isoforms M D’Ascenzio, P Guglielmi, S Carradori, D Secci, R Florio, A Mollica, ... Journal of Enzyme Inhibition and Medicinal Chemistry 32 (1), 51-59, 2017 | 53 | 2017 |
| Exploring new Probenecid-based carbonic anhydrase inhibitors: Synthesis, biological evaluation and docking studies A Mollica, R Costante, A Akdemir, S Carradori, A Stefanucci, ... Bioorganic & Medicinal Chemistry 23 (17), 5311-5318, 2015 | 51 | 2015 |
| Synthesis of a new series of dithiocarbamates with effective human carbonic anhydrase inhibitory activity and antiglaucoma action M Bozdag, F Carta, D Vullo, A Akdemir, S Isik, C Lanzi, A Scozzafava, ... Bioorganic & Medicinal Chemistry 23 (10), 2368-2376, 2015 | 49 | 2015 |
| Selective inhibition of human carbonic anhydrases by novel amide derivatives of probenecid: synthesis, biological evaluation and molecular modelling studies M D’Ascenzio, S Carradori, D Secci, D Vullo, M Ceruso, A Akdemir, ... Bioorganic & Medicinal Chemistry 22 (15), 3982-3988, 2014 | 44 | 2014 |
| Computational investigation of the selectivity of salen and tetrahydrosalen compounds towards the tumor-associated hCA XII isozyme A Akdemir, C De Monte, S Carradori, CT Supuran Journal of Enzyme Inhibition and Medicinal Chemistry 30 (1), 114-118, 2015 | 43 | 2015 |
| A Gq/11-coupled mutant histamine H1 receptor F435A activated solely by synthetic ligands (RASSL) M Bruysters, A Jongejan, A Akdemir, RA Bakker, R Leurs Journal of Biological Chemistry 280 (41), 34741-34746, 2005 | 39 | 2005 |
| New amide derivatives of Probenecid as selective inhibitors of carbonic anhydrase IX and XII: biological evaluation and molecular modelling studies S Carradori, A Mollica, M Ceruso, M D’Ascenzio, C De Monte, P Chimenti, ... Bioorganic & Medicinal Chemistry 23 (13), 2975-2981, 2015 | 38 | 2015 |
| Acetylcholine binding protein (AChBP) as template for hierarchical in silico screening procedures to identify structurally novel ligands for the nicotinic receptors A Akdemir, P Rucktooa, A Jongejan, R Van Elk, S Bertrand, TK Sixma, ... Bioorganic & medicinal chemistry 19 (20), 6107-6119, 2011 | 38 | 2011 |
| Novel sulfonamide-containing 2-indolinones that selectively inhibit tumor-associated alpha carbonic anhydrases N Karalı, A Akdemir, F Göktaş, PE Elma, A Angeli, M Kızılırmak, ... Bioorganic & Medicinal Chemistry 25 (14), 3714-3718, 2017 | 33 | 2017 |
| Isatin analogs as novel inhibitors of Candida spp. β-carbonic anhydrase enzymes A Akdemir, Ö Güzel-Akdemir, N Karalı, CT Supuran Bioorganic & medicinal chemistry 24 (8), 1648-1652, 2016 | 30 | 2016 |
Simone Carradori"G. d'Annunzio" University of Chieti-PescaraEmail verificata su unich.it
