| Chemistry of the cysteine sensors in Kelch-like ECH-associated protein 1 R Holland, JC Fishbein Antioxidants & redox signaling 13 (11), 1749-1761, 2010 | 129 | 2010 |
| Prospective type 1 and type 2 disulfides of Keap1 protein R Holland, AE Hawkins, AL Eggler, AD Mesecar, D Fabris, JC Fishbein Chemical research in toxicology 21 (10), 2051-2060, 2008 | 113 | 2008 |
| The Nitric Oxide Prodrug JS-K Is Effective against Non–Small-Cell Lung Cancer Cells In Vitro and In Vivo: Involvement of Reactive Oxygen Species AE Maciag, H Chakrapani, JE Saavedra, NL Morris, RJ Holland, ... Journal of Pharmacology and Experimental Therapeutics 336 (2), 313-320, 2011 | 87 | 2011 |
| Synthesis and Chemical and Biological Comparison of Nitroxyl-and Nitric Oxide-Releasing Diazeniumdiolate-Based Aspirin Derivatives D Basudhar, G Bharadwaj, RY Cheng, S Jain, S Shi, JL Heinecke, ... Journal of medicinal chemistry 56 (20), 7804-7820, 2013 | 74 | 2013 |
| Nitric oxide-releasing prodrug triggers cancer cell death through deregulation of cellular redox balance AE Maciag, RJ Holland, YS Robert Cheng, LG Rodriguez, JE Saavedra, ... Redox biology 1 (1), 115-124, 2013 | 64 | 2013 |
| The liver-selective NO donor, V-PYRRO/NO, protects against liver steatosis and improves postprandial glucose tolerance in mice fed high fat diet E Maslak, P Zabielski, K Kochan, K Kus, A Jasztal, B Sitek, B Proniewski, ... Biochemical pharmacology 93 (3), 389-400, 2015 | 41 | 2015 |
| Nitric Oxide (NO) Releasing Poly ADP-ribose Polymerase 1 (PARP-1) Inhibitors Targeted to Glutathione S-Transferase P1-Overexpressing Cancer Cells AE Maciag, RJ Holland, Y Kim, V Kumari, CE Luthers, WS Sehareen, ... Journal of medicinal chemistry 57 (6), 2292-2302, 2014 | 39 | 2014 |
| Hydrogen peroxide is a second messenger in phase 2 enzyme induction by cancer chemopreventive dithiolethiones R Holland, M Navamal, M Velayutham, JL Zweier, TW Kensler, ... Chemical research in toxicology 22 (8), 1427-1434, 2009 | 39 | 2009 |
| Irreversible Inhibition of Glutathione S-Transferase by Phenethyl Isothiocyanate (PEITC), a Dietary Cancer Chemopreventive Phytochemical V Kumari, MA Dyba, RJ Holland, YH Liang, SV Singh, X Ji PLoS One 11 (9), e0163821, 2016 | 33 | 2016 |
| “Click” Reaction in Conjunction with Diazeniumdiolate Chemistry: Developing High-Load Nitric Oxide Donors OA Oladeinde, SY Hong, RJ Holland, AE Maciag, LK Keefer, JE Saavedra, ... Organic letters 12 (19), 4256-4259, 2010 | 32 | 2010 |
| Hepatoselective Nitric Oxide (NO) Donors, V-PYRRO/NO and V-PROLI/NO, in Nonalcoholic Fatty Liver Disease: A Comparison of Antisteatotic Effects with the Biotransformation and … K Kus, M Walczak, E Maslak, A Zakrzewska, A Gonciarz-Dytman, ... Drug Metabolism and Disposition 43 (7), 1028-1036, 2015 | 25 | 2015 |
| Mechanism of action for the cytotoxic effects of the nitric oxide prodrug JS-K in murine erythroleukemia cells MZ Kaczmarek, RJ Holland, SA Lavanier, JA Troxler, VI Fesenkova, ... Leukemia research 38 (3), 377-382, 2014 | 23 | 2014 |
| Direct Reaction of Amides with Nitric Oxide To Form Diazeniumdiolates RJ Holland, JR Klose, JR Deschamps, Z Cao, LK Keefer, JE Saavedra The Journal of organic chemistry 79 (19), 9389-9393, 2014 | 22 | 2014 |
| Structural modifications modulate stability of glutathione-activated arylated diazeniumdiolate prodrugs RS Nandurdikar, AE Maciag, RJ Holland, Z Cao, PJ Shami, LM Anderson, ... Bioorganic & medicinal chemistry 20 (9), 3094-3099, 2012 | 19 | 2012 |
| PABA/NO lead optimization: Improved targeting of cytotoxicity to glutathione S-transferase P1-overexpressing cancer cells Y Kim, AE Maciag, Z Cao, JR Deschamps, JE Saavedra, LK Keefer, ... Bioorganic & medicinal chemistry 23 (15), 4980-4988, 2015 | 15 | 2015 |
| Enzymatic generation of the NO/HNO-releasing IPA/NO anion at controlled rates in physiological media using β-galactosidase RJ Holland, R Paulisch, Z Cao, LK Keefer, JE Saavedra, S Donzelli Nitric Oxide 35, 131-136, 2013 | 12 | 2013 |
| O2-Functionalized Methylamine Diazeniumdiolates: Evidence for E⇄ Z Equilibration in an Acyclic System D Biswas, RJ Holland, JR Deschamps, Z Cao, LK Keefer, JE Saavedra The Journal of organic chemistry 77 (23), 10804-10810, 2012 | 11 | 2012 |
| Decoding Nitric Oxide Release Rates of Amine-Based Diazeniumdiolates YN Wang, J Collins, RJ Holland, LK Keefer, J Ivanic The Journal of Physical Chemistry A 117 (30), 6671-6677, 2013 | 7 | 2013 |
| Cross-Linking Protein Glutathionylation Mediated by O2-Arylated Bis-Diazeniumdiolate “Double JS-K” RJ Holland, AE Maciag, V Kumar, L Shi, JE Saavedra, RK Prud'homme, ... Chemical research in toxicology 25 (12), 2670-2677, 2012 | 7 | 2012 |
| Thiol modification by pharmacologically active agents of the diazeniumdiolate class AE Maciag, RJ Holland, JE Saavedra, H Chakrapani, PJ Shami, ... Forum on immunopathological diseases and therapeutics 3 (2), 2012 | 3 | 2012 |
Harinath ChakrapaniProfessorVerified email at iiserpune.ac.in
