The Trp-cage: optimizing the stability of a globular miniprotein B Barua, JC Lin, VD Williams, P Kummler, JW Neidigh, NH Andersen Protein Engineering, Design & Selection 21 (3), 171-185, 2008 | 230 | 2008 |
A pre-existing hydrophobic collapse in the unfolded state of an ultrafast folding protein KH Mok, LT Kuhn, M Goez, IJ Day, JC Lin, NH Andersen, PJ Hore Nature 447 (7140), 106-109, 2007 | 198 | 2007 |
The Helical Alanine Controversy: An (Ala)6 Insertion Dramatically Increases Helicity JC Lin, B Barua, NH Andersen Journal of the American Chemical Society 126 (42), 13679-13684, 2004 | 60 | 2004 |
Determining the compatible orientation workspace of Stewart–Gough parallel manipulators KY Tsai, JC Lin Mechanism and machine theory 41 (10), 1168-1184, 2006 | 49 | 2006 |
Biophysical techniques for characterizing the higher order structure and interactions of monoclonal antibodies Y Gokarn, S Agarwal, K Arthur, A Bepperling, ES Day, D Filoti, DG Greene, ... State-of-the-Art and Emerging Technologies for Therapeutic Monoclonal …, 2015 | 42 | 2015 |
High-resolution mapping of epitopes on the C2 domain of factor VIII by analysis of point mutants using surface plasmon resonance PCT Nguyen, KB Lewis, RA Ettinger, JT Schuman, JC Lin, JF Healey, ... Blood, The Journal of the American Society of Hematology 123 (17), 2732-2739, 2014 | 40 | 2014 |
Crystal and NMR structures of a Trp-cage mini-protein benchmark for computational fold prediction M Scian, JC Lin, I Le Trong, GI Makhatadze, RE Stenkamp, NH Andersen Proceedings of the National Academy of Sciences 109 (31), 12521-12525, 2012 | 38 | 2012 |
Assessing the utility of circular dichroism and FTIR spectroscopy in monoclonal-antibody comparability studies JC Lin, ZK Glover, A Sreedhara Journal of Pharmaceutical Sciences 104 (12), 4459-4466, 2015 | 35 | 2015 |
Toward in silico CMC: An industrial collaborative approach to model‐based process development D Roush, D Asthagiri, DK Babi, S Benner, C Bilodeau, G Carta, P Ernst, ... Biotechnology and bioengineering 117 (12), 3986-4000, 2020 | 31 | 2020 |
Deficiency of the specific granule proteins, R‐binder/transcobalamin I and lactoferrin, in plasma and saliva: A new disorder JC Lin, N Borregaard, HA Liebman, R Carmel American journal of medical genetics 100 (2), 145-151, 2001 | 24 | 2001 |
Six Amino Acid Residues in a 1200 Å2 Interface Mediate Binding of Factor VIII to an IgG4κ Inhibitory Antibody JC Lin, RA Ettinger, JT Schuman, AH Zhang, M Wamiq-Adhami, ... PLoS One 10 (1), e0116577, 2015 | 22* | 2015 |
Highland games: A benchmarking exercise in predicting biophysical and drug properties of monoclonal antibodies from amino acid sequences J Coffman, B Marques, R Orozco, M Aswath, H Mohammad, ... Biotechnology and Bioengineering 117 (7), 2100-2115, 2020 | 10 | 2020 |
Best practices for aggregate quantitation of antibody therapeutics by sedimentation velocity analytical ultracentrifugation GM Bou-Assaf, IL Budyak, M Brenowitz, ES Day, D Hayes, J Hill, ... Journal of pharmaceutical sciences 111 (7), 2121-2133, 2022 | 9 | 2022 |
Subcutaneous HER2 antibody formulations J Eng-Wong, W Kirschbrown, T Khan, J Lin, S Alavattam, A Garg, ... US Patent 10,849,849, 2020 | 9 | 2020 |
Lysine and arginine residues do not increase the helicity of alanine-rich peptide helices JM Stewart, JC Lin, NH Andersen Chemical communications, 4765-4767, 2008 | 8 | 2008 |
Impact of silicone oil on free fatty acid particle formation due to Polysorbate 20 degradation R Fish, J Lin, N Doshi Pharmaceutical Research 37, 1-15, 2020 | 7 | 2020 |
Six-DOF parallel manipulators with maximal singularity-free joint space or workspace KY Tsai, JC Lin, Y Lo Robotica 32 (3), 401-411, 2014 | 7 | 2014 |
Deciphering deamidation and isomerization in therapeutic proteins: Effect of neighboring residue FJ Irudayanathan, J Zarzar, J Lin, S Izadi MAbs 14 (1), 2143006, 2022 | 6 | 2022 |
Chemical shifts, the ultimate test of polypeptide folding cooperativity NH Andersen, B Barua, RM Fesinmeyer, FM Hudson, J Lin, A Euser, ... Peptides, 824-825, 2002 | 5 | 2002 |
Subcutaneous her2 antibody formulations J Eng-Wong, W Kirschbrown, TA Khan, J Lin, S Alavattam, A Garg, ... US Patent App. 16/952,670, 2021 | 4 | 2021 |