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Leon Tejwani
Leon Tejwani
Denali Therapeutics
Verified email at dnli.com
Title
Cited by
Cited by
Year
Modeling of TREX1-dependent autoimmune disease using human stem cells highlights L1 accumulation as a source of neuroinflammation
CA Thomas, L Tejwani, CA Trujillo, PD Negraes, RH Herai, P Mesci, ...
Cell Stem Cell 21 (3), 319-331. e8, 2017
2852017
Cortical organoids model early brain development disrupted by 16p11. 2 copy number variants in autism
J Urresti, P Zhang, P Moran-Losada, NK Yu, PD Negraes, CA Trujillo, ...
Molecular psychiatry 26 (12), 7560-7580, 2021
86*2021
Blocking Zika virus vertical transmission
P Mesci, A Macia, SM Moore, SA Shiryaev, A Pinto, CT Huang, L Tejwani, ...
Scientific Reports 8 (1), 1-13, 2018
792018
Pharmacological reversal of synaptic and network pathology in human MECP2‐KO neurons and cortical organoids
CA Trujillo, JW Adams, PD Negraes, C Carromeu, L Tejwani, A Acab, ...
EMBO Molecular Medicine 13 (1), e12523, 2021
632021
Modeling neuro-immune interactions during Zika virus infection
P Mesci, A Macia, CN LaRock, L Tejwani, IR Fernandes, NA Suarez, ...
Human Molecular Genetics 27 (1), 41-52, 2018
562018
Pathogenic mechanisms underlying spinocerebellar ataxia type 1
L Tejwani, J Lim
Cellular and Molecular Life Sciences 77 (20), 4015-4029, 2020
252020
Association of CACNA1C with bipolar disorder among the Pakistani population
M Khalid, TM Driessen, JS Lee, L Tejwani, A Rasool, M Saqlain, PA Shiaq, ...
Gene 664, 119-126, 2018
212018
Genetic risk of autism spectrum disorder in a Pakistani population
M Khalid, H Raza, T M. Driessen, P J. Lee, L Tejwani, A Sami, M Nawaz, ...
Genes 11 (10), 1206, 2020
172020
Microglia regulate brain progranulin levels through the endocytosis/lysosomal pathway
T Dong, L Tejwani, Y Jung, H Kokubu, K Luttik, TM Driessen, J Lim
JCI insight 6 (22), 2021
82021
Differential effects of Wnt-β-catenin signaling in Purkinje cells and Bergmann glia in spinocerebellar ataxia type 1
K Luttik, L Tejwani, H Ju, T Driessen, CJLM Smeets, CR Edamakanti, ...
Proceedings of the National Academy of Sciences 119 (34), e2208513119, 2022
7*2022
Longitudinal single-cell transcriptional dynamics throughout neurodegeneration in SCA1
L Tejwani, NG Ravindra, C Lee, Y Cheng, B Nguyen, K Luttik, L Ni, ...
Neuron, 2021.10. 22.465444, 2023
52023
Activity of retrotransposons in stem cells and differentiated cells
A Macia, L Tejwani, P Mesci, A Muotri, JL Garcia-Perez
Human Retrotransposons in Health and Disease, 127-156, 2017
52017
Reduction of nemo-like kinase increases lysosome biogenesis and ameliorates TDP-43–related neurodegeneration
L Tejwani, Y Jung, H Kokubu, S Sowmithra, L Ni, C Lee, B Sanders, ...
The Journal of Clinical Investigation 133 (16), 2023
32023
A Novel Missense Mutation in ERCC8 Co-Segregates with Cerebellar Ataxia in a Consanguineous Pakistani Family
Z Gauhar, L Tejwani, U Abdullah, S Saeed, S Shafique, M Badshah, ...
Cells 11 (19), 3090, 2022
12022
Exploring the role of protein quality control in aging and age-associated neurodegenerative diseases
N Gogia, V Olmos, F Haidery, K Luttik, L Tejwani, J Lim
Anti-Aging Drug Discovery on the Basis of Hallmarks of Aging, 139-171, 2022
2022
Uncovering novel roles for glia in neurodegenerative diseases
LL Tejwani
2021
Association of CACNA1C with Bipolar disorder among the Pakistani population.
MK Madiha Khalid, TM Driessen, LJS Lee JongSeo, L Tejwani, ...
2018
Hunting for the mutant without the MAP (K)
L Tejwani, J Lim
Cell Research 27 (12), 1403-1404, 2017
2017
Genome Editing in Stem Cells
L Tejwani, CA Trujillo, CA Thomas, AR Muotri
Working with Stem Cells, 287, 2016
2016
Using induced pluripotent stem cells and CRISPR/Cas9-mediated targeted mutagenesis to create a model to study Aicardi-Goutières Syndrome
LL Tejwani
UC San Diego, 2014
2014
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Articles 1–20