COVID-19 and drug-induced liver injury: a problem of plenty or a petty point? J Boeckmans, RM Rodrigues, T Demuyser, D Pierard, T Vanhaecke, ... Archives of toxicology 94, 1367-1369, 2020 | 154 | 2020 |
Anti-NASH drug development hitches a lift on PPAR agonism J Boeckmans, A Natale, M Rombaut, K Buyl, V Rogiers, J De Kock, ... Cells 9 (1), 37, 2019 | 98 | 2019 |
Neutrophil-to-hepatocyte communication via LDLR-dependent miR-223–enriched extracellular vesicle transfer ameliorates nonalcoholic steatohepatitis Y He, RM Rodrigues, X Wang, W Seo, J Ma, S Hwang, Y Fu, E Trojnár, ... The Journal of clinical investigation 131 (3), 2021 | 94 | 2021 |
Assaying cellular viability using the neutral red uptake assay G Ates, T Vanhaecke, V Rogiers, RM Rodrigues Cell Viability Assays: Methods and Protocols, 19-26, 2017 | 90 | 2017 |
Mesoderm-derived stem cells: the link between the transcriptome and their differentiation potential J De Kock, M Najar, J Bolleyn, F Al Battah, RM Rodrigues, K Buyl, ... Stem cells and development 21 (18), 3309-3323, 2012 | 64 | 2012 |
In vitro assessment of hepatotoxicity by metabolomics: a review M Cuykx, RM Rodrigues, K Laukens, T Vanhaecke, A Covaci Archives of Toxicology 92, 3007-3029, 2018 | 57 | 2018 |
Interplay of liver–heart inflammatory axis and cannabinoid 2 receptor signaling in an experimental model of hepatic cardiomyopathy C Matyas, K Erdelyi, E Trojnar, S Zhao, ZV Varga, J Paloczi, ... Hepatology 71 (4), 1391-1407, 2020 | 54 | 2020 |
Human skin-derived stem cells as a novel cell source for in vitro hepatotoxicity screening of pharmaceuticals RM Rodrigues, J De Kock, S Branson, M Vinken, K Meganathan, ... Stem cells and development 23 (1), 44-55, 2014 | 54 | 2014 |
Toxicogenomics-based prediction of acetaminophen-induced liver injury using human hepatic cell systems RM Rodrigues, A Heymans, V De Boe, A Sachinidis, U Chaudhari, ... Toxicology letters 240 (1), 50-59, 2016 | 53 | 2016 |
Human-based systems: Mechanistic NASH modelling just around the corner? J Boeckmans, A Natale, K Buyl, V Rogiers, J De Kock, T Vanhaecke, ... Pharmacological research 134, 257-267, 2018 | 51 | 2018 |
Protective and Detrimental Roles of p38α Mitogen‐Activated Protein Kinase in Different Stages of Nonalcoholic Fatty Liver Disease S Hwang, X Wang, RM Rodrigues, J Ma, Y He, W Seo, SH Park, SJ Kim, ... Hepatology 72 (3), 873-891, 2020 | 47 | 2020 |
Metabolomics profiling of steatosis progression in HepaRG® cells using sodium valproate M Cuykx, L Claes, RM Rodrigues, T Vanhaecke, A Covaci Toxicology letters 286, 22-30, 2018 | 44 | 2018 |
Autofluorescence microscopy: a non-destructive tool to monitor mitochondrial toxicity RM Rodrigues, P Macko, T Palosaari, MP Whelan Toxicology letters 206 (3), 281-288, 2011 | 44 | 2011 |
Assessment of an automated in vitro basal cytotoxicity test system based on metabolically-competent cells RM Rodrigues, M Bouhifd, G Bories, MG Sacco, L Gribaldo, M Fabbri, ... Toxicology in Vitro 27 (2), 760-767, 2013 | 42 | 2013 |
Chronic-plus-binge alcohol intake induces production of proinflammatory mtDNA-enriched extracellular vesicles and steatohepatitis via ASK1/p38MAPKα-dependent mechanisms J Ma, H Cao, RM Rodrigues, M Xu, T Ren, Y He, S Hwang, D Feng, ... JCI insight 5 (14), 2020 | 39 | 2020 |
Inhibition of connexin hemichannels alleviates non-alcoholic steatohepatitis in mice J Willebrords, B Cogliati, IVA Pereira, TC da Silva, S Crespo Yanguas, ... Scientific reports 7 (1), 8268, 2017 | 39 | 2017 |
Omics-based responses induced by bosentan in human hepatoma HepaRG cell cultures RM Rodrigues, L Kollipara, U Chaudhari, A Sachinidis, RP Zahedi, ... Archives of toxicology 92, 1939-1952, 2018 | 37 | 2018 |
Metabolomics analysis of the toxicity pathways of triphenyl phosphate in HepaRG cells and comparison to oxidative stress mechanisms caused by acetaminophen N Van den Eede, M Cuykx, RM Rodrigues, K Laukens, H Neels, A Covaci, ... Toxicology in Vitro 29 (8), 2045-2054, 2015 | 36 | 2015 |
E-selectin-dependent inflammation and lipolysis in adipose tissue exacerbate steatosis-to-NASH progression via S100A8/9 RM Rodrigues, Y He, S Hwang, A Bertola, B Mackowiak, YA Ahmed, ... Cellular and molecular gastroenterology and hepatology 13 (1), 151-171, 2022 | 30 | 2022 |
In vitro assessment of drug-induced liver steatosis based on human dermal stem cell-derived hepatic cells RM Rodrigues, S Branson, V De Boe, A Sachinidis, V Rogiers, J De Kock, ... Archives of toxicology 90, 677-689, 2016 | 30 | 2016 |