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David J Brockwell
David J Brockwell
Verified email at leeds.ac.uk - Homepage
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Cited by
Cited by
Year
Pulling geometry defines the mechanical resistance of a β-sheet protein
DJ Brockwell, E Paci, RC Zinober, GS Beddard, PD Olmsted, DA Smith, ...
Nature Structural & Molecular Biology 10 (9), 731-737, 2003
4472003
Intermediates: ubiquitous species on folding energy landscapes?
DJ Brockwell, SE Radford
Current opinion in structural biology 17 (1), 30-37, 2007
2952007
Tuning the elastic modulus of hydrated collagen fibrils
CA Grant, DJ Brockwell, SE Radford, NH Thomson
Biophysical journal 97 (11), 2985-2992, 2009
1922009
Mechanically unfolding the small, topologically simple protein L
DJ Brockwell, GS Beddard, E Paci, DK West, PD Olmsted, DA Smith, ...
Biophysical journal 89 (1), 506-519, 2005
1922005
Lateral opening in the intact β-barrel assembly machinery captured by cryo-EM
MG Iadanza, AJ Higgins, B Schiffrin, AN Calabrese, DJ Brockwell, ...
Nature communications 7 (1), 12865, 2016
1902016
Protein folding mechanisms: new methods and emerging ideas
DJ Brockwell, DA Smith, SE Radford
Current opinion in structural biology 10 (1), 16-25, 2000
1742000
Force mode atomic force microscopy as a tool for protein folding studies
RB Best, DJ Brockwell, JL Toca-Herrera, AW Blake, DA Smith, ...
Analytica Chimica Acta 479 (1), 87-105, 2003
1622003
Effects of hydration on the mechanical response of individual collagen fibrils
CA Grant, DJ Brockwell, SE Radford, NH Thomson
Applied Physics Letters 92 (23), 2008
1602008
The effect of core destabilization on the mechanical resistance of I27
DJ Brockwell, GS Beddard, J Clarkson, RC Zinober, AW Blake, J Trinick, ...
Biophysical journal 83 (1), 458-472, 2002
1592002
The transition state for folding of an outer membrane protein
GHM Huysmans, SA Baldwin, DJ Brockwell, SE Radford
Proceedings of the National Academy of Sciences 107 (9), 4099-4104, 2010
1532010
A short motif in the N-terminal region of α-synuclein is critical for both aggregation and function
CPA Doherty, SM Ulamec, R Maya-Martinez, SC Good, J Makepeace, ...
Nature structural & molecular biology 27 (3), 249-259, 2020
1342020
Mechanical resistance of proteins explained using simple molecular models
DK West, DJ Brockwell, PD Olmsted, SE Radford, E Paci
Biophysical journal 90 (1), 287-297, 2006
1322006
Role of the lipid bilayer in outer membrane protein folding in Gram-negative bacteria
JE Horne, DJ Brockwell, SE Radford
Journal of Biological Chemistry 295 (30), 10340-10367, 2020
1012020
Inducing protein aggregation by extensional flow
J Dobson, A Kumar, LF Willis, R Tuma, DR Higazi, R Turner, DC Lowe, ...
Proceedings of the National Academy of Sciences 114 (18), 4673-4678, 2017
992017
Skp is a multivalent chaperone of outer-membrane proteins
B Schiffrin, AN Calabrese, PWA Devine, SA Harris, AE Ashcroft, ...
Nature structural & molecular biology 23 (9), 786-793, 2016
982016
De novo design of transmembrane β barrels
AA Vorobieva, P White, B Liang, JE Horne, AK Bera, CM Chow, S Gerben, ...
Science 371 (6531), eabc8182, 2021
962021
Mechanically unfolding proteins: the effect of unfolding history and the supramolecular scaffold
RC Zinober, DJ Brockwell, GS Beddard, AW Blake, PD Olmsted, ...
Protein science 11 (12), 2759-2765, 2002
922002
An in vivo platform for identifying inhibitors of protein aggregation
JC Saunders, LM Young, RA Mahood, MP Jackson, CH Revill, RJ Foster, ...
Nature chemical biology 12 (2), 94-101, 2016
912016
Towards design principles for determining the mechanical stability of proteins
T Hoffmann, KM Tych, ML Hughes, DJ Brockwell, L Dougan
Physical Chemistry Chemical Physics 15 (38), 15767-15780, 2013
802013
Gating of TonB-dependent transporters by substrate-specific forced remodelling
SJ Hickman, REM Cooper, L Bellucci, E Paci, DJ Brockwell
Nature communications 8 (1), 14804, 2017
782017
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