David J Brockwell
David J Brockwell
Associate Professor, University of Leeds
Verified email at leeds.ac.uk - Homepage
Cited by
Cited by
Pulling geometry defines the mechanical resistance of a β-sheet protein
DJ Brockwell, E Paci, RC Zinober, GS Beddard, PD Olmsted, DA Smith, ...
Nature Structural & Molecular Biology 10 (9), 731-737, 2003
Intermediates: ubiquitous species on folding energy landscapes?
DJ Brockwell, SE Radford
Current opinion in structural biology 17 (1), 30-37, 2007
Mechanically unfolding the small, topologically simple protein L
DJ Brockwell, GS Beddard, E Paci, DK West, PD Olmsted, DA Smith, ...
Biophysical journal 89 (1), 506-519, 2005
Protein folding mechanisms: new methods and emerging ideas
DJ Brockwell, DA Smith, SE Radford
Current opinion in structural biology 10 (1), 16-25, 2000
Tuning the elastic modulus of hydrated collagen fibrils
CA Grant, DJ Brockwell, SE Radford, NH Thomson
Biophysical journal 97 (11), 2985-2992, 2009
Force mode atomic force microscopy as a tool for protein folding studies
RB Best, DJ Brockwell, JL Toca-Herrera, AW Blake, DA Smith, ...
Analytica Chimica Acta 479 (1), 87-105, 2003
The effect of core destabilization on the mechanical resistance of I27
DJ Brockwell, GS Beddard, J Clarkson, RC Zinober, AW Blake, J Trinick, ...
Biophysical journal 83 (1), 458-472, 2002
Mechanical resistance of proteins explained using simple molecular models
DK West, DJ Brockwell, PD Olmsted, SE Radford, E Paci
Biophysical journal 90 (1), 287-297, 2006
The transition state for folding of an outer membrane protein
GHM Huysmans, SA Baldwin, DJ Brockwell, SE Radford
Proceedings of the National Academy of Sciences 107 (9), 4099-4104, 2010
Effects of hydration on the mechanical response of individual collagen fibrils
CA Grant, DJ Brockwell, SE Radford, NH Thomson
Applied Physics Letters 92 (23), 233902, 2008
Lateral opening in the intact β-barrel assembly machinery captured by cryo-EM
MG Iadanza, AJ Higgins, B Schiffrin, AN Calabrese, DJ Brockwell, ...
Nature communications 7 (1), 1-12, 2016
Mechanically unfolding proteins: the effect of unfolding history and the supramolecular scaffold
RC Zinober, DJ Brockwell, GS Beddard, AW Blake, PD Olmsted, ...
Protein science 11 (12), 2759-2765, 2002
The N-terminal helix is a post-assembly clamp in the bacterial outer membrane protein PagP
GHM Huysmans, SE Radford, DJ Brockwell, SA Baldwin
Journal of molecular biology 373 (3), 529-540, 2007
Unravelling the design principles for single protein mechanical strength
N Crampton, DJ Brockwell
Current opinion in structural biology 20 (4), 508-517, 2010
Skp is a multivalent chaperone of outer-membrane proteins
B Schiffrin, AN Calabrese, PWA Devine, SA Harris, AE Ashcroft, ...
Nature structural & molecular biology 23 (9), 786-793, 2016
An in vivo platform for identifying inhibitors of protein aggregation
JC Saunders, LM Young, RA Mahood, MP Jackson, CH Revill, RJ Foster, ...
Nature chemical biology 12 (2), 94-101, 2016
Identification of a mechanical rheostat in the hydrophobic core of protein L
DP Sadler, E Petrik, Y Taniguchi, JR Pullen, M Kawakami, SE Radford, ...
Journal of molecular biology 393 (1), 237-248, 2009
Viscoelastic study of the mechanical unfolding of a protein by AFM
M Kawakami, K Byrne, DJ Brockwell, SE Radford, DA Smith
Biophysical journal 91 (2), L16-L18, 2006
Urea-induced unfolding of the immunity protein Im9 monitored by spFRET
T Tezuka-Kawakami, C Gell, DJ Brockwell, SE Radford, DA Smith
Biophysical journal 91 (5), L42-L44, 2006
Towards design principles for determining the mechanical stability of proteins
T Hoffmann, KM Tych, ML Hughes, DJ Brockwell, L Dougan
Physical Chemistry Chemical Physics 15 (38), 15767-15780, 2013
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