Coxsackievirus B1 is associated with induction of β-cell autoimmunity that portends type 1 diabetes OH Laitinen, H Honkanen, O Pakkanen, S Oikarinen, MM Hankaniemi, ... Diabetes 63 (2), 446-455, 2014 | 327 | 2014 |
Coxsackievirus B1 infections are associated with the initiation of insulin-driven autoimmunity that progresses to type 1 diabetes AB Sioofy-Khojine, J Lehtonen, N Nurminen, OH Laitinen, S Oikarinen, ... Diabetologia 61, 1193-1202, 2018 | 106 | 2018 |
Detection of enteroviruses in stools precedes islet autoimmunity by several months: possible evidence for slowly operating mechanisms in virus-induced autoimmunity H Honkanen, S Oikarinen, N Nurminen, OH Laitinen, H Huhtala, ... Diabetologia 60 (3), 424-431, 2017 | 103 | 2017 |
Characterization of recombinant human growth differentiation factor-9 signaling in ovarian granulosa cells DG Mottershead, MM Pulkki, P Muggalla, A Pasternack, M Tolonen, ... Molecular and Cellular Endocrinology 283 (1-2), 58-67, 2008 | 80 | 2008 |
A Coxsackievirus B vaccine protects against virus-induced diabetes in an experimental mouse model of type 1 diabetes VM Stone, MM Hankaniemi, E Svedin, A Sioofy-Khojine, S Oikarinen, ... Diabetologia 61, 476-481, 2018 | 78 | 2018 |
A hexavalent Coxsackievirus B vaccine is highly immunogenic and has a strong protective capacity in mice and nonhuman primates VM Stone, MM Hankaniemi, OH Laitinen, AB Sioofy-Khojine, A Lin, ... Science Advances 6 (19), eaaz2433, 2020 | 75 | 2020 |
A covalently dimerized recombinant human bone morphogenetic protein-15 variant identifies bone morphogenetic protein receptor type 1B as a key cell surface receptor on ovarian … MM Pulkki, DG Mottershead, AH Pasternack, P Muggalla, H Ludlow, ... Endocrinology 153 (3), 1509-1518, 2012 | 57 | 2012 |
The bioactivity of human bone morphogenetic protein-15 is sensitive to C-terminal modification: characterization of the purified untagged processed mature region MM Pulkki, S Myllymaa, A Pasternack, S Lun, H Ludlow, A Al-Qahtani, ... Molecular and cellular endocrinology 332 (1-2), 106-115, 2011 | 52 | 2011 |
Optimized production and purification of Coxsackievirus B1 vaccine and its preclinical evaluation in a mouse model MM Hankaniemi, OH Laitinen, VM Stone, A Sioofy-Khojine, JAE Määttä, ... Vaccine 35 (30), 3718-3725, 2017 | 41 | 2017 |
Human enterovirus 71 strains in the background population and in hospital patients in Finland H Honkanen, S Oikarinen, O Pakkanen, T Ruokoranta, MM Pulkki, ... Journal of Clinical Virology 56 (4), 348-353, 2013 | 39 | 2013 |
Modular vaccine platform based on the norovirus-like particle V Lampinen, S Heinimäki, OH Laitinen, M Pesu, MM Hankaniemi, ... Journal of nanobiotechnology 19, 1-14, 2021 | 26 | 2021 |
A comparative study of the effect of UV and formalin inactivation on the stability and immunogenicity of a Coxsackievirus B1 vaccine MM Hankaniemi, VM Stone, AB Sioofy-Khojine, S Heinimäki, V Marjomäki, ... Vaccine 37 (40), 5962-5971, 2019 | 26 | 2019 |
Coxsackievirus B vaccines prevent infection-accelerated diabetes in NOD mice and have No disease-inducing effect VM Stone, M Butrym, MM Hankaniemi, AB Sioofy-Khojine, VP Hytönen, ... Diabetes 70 (12), 2871-2878, 2021 | 24 | 2021 |
Inhibition of oocyte growth factors in vivo modulates ovarian folliculogenesis in neonatal and immature mice S Myllymaa, A Pasternack, DG Mottershead, M Poutanen, MM Pulkki, ... Reproduction 139 (3), 587-598, 2010 | 23 | 2010 |
A novel rat CVB1-VP1 monoclonal antibody 3A6 detects a broad range of enteroviruses NVV Saarinen, JE Laiho, SJ Richardson, M Zeissler, VM Stone, ... Scientific reports 8 (1), 33, 2018 | 22 | 2018 |
Combination of three virus-derived nanoparticles as a vaccine against enteric pathogens; enterovirus, norovirus and rotavirus S Heinimäki, MM Hankaniemi, AB Sioofy-Khojine, OH Laitinen, H Hyöty, ... Vaccine 37 (51), 7509-7518, 2019 | 21 | 2019 |
Formalin treatment increases the stability and immunogenicity of coxsackievirus B1 VLP vaccine MM Hankaniemi, VM Stone, T Andrejeff, S Heinimäki, AB Sioofy-Khojine, ... Antiviral Research 171, 104595, 2019 | 19 | 2019 |
New Coxsackievirus 2Apro and 3Cpro protease antibodies for virus detection and discovery of pathogenic mechanisms OH Laitinen, E Svedin, S Kapell, MM Hankaniemi, PG Larsson, ... Journal of virological methods 255, 29-37, 2018 | 17 | 2018 |
Structural insight into CVB3-VLP non-adjuvanted vaccine MM Hankaniemi, MA Baikoghli, VM Stone, L Xing, O Väätäinen, ... Microorganisms 8 (9), 1287, 2020 | 12 | 2020 |
Antigenicity and immunogenicity of HA2 and M2e influenza virus antigens conjugated to norovirus-like, VP1 capsid-based particles by the SpyTag/SpyCatcher technology S Heinimäki, V Lampinen, K Tamminen, MM Hankaniemi, M Malm, ... Virology 566, 89-97, 2022 | 10 | 2022 |