Giuseppe Floresta
Giuseppe Floresta
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The search for potent, small‐molecule HDACIs in cancer treatment: a decade after vorinostat
C Zagni, G Floresta, G Monciino, A Rescifina
Medicinal research reviews 37 (6), 1373-1428, 2017
Adipocyte fatty acid binding protein 4 (FABP4) inhibitors. A comprehensive systematic review
G Floresta, V Pistarą, E Amata, M Dichiara, A Marrazzo, O Prezzavento, ...
European journal of medicinal chemistry 138, 854-873, 2017
Mild Friedel–Crafts Reactions inside a Hexameric Resorcinarene Capsule: C− Cl Bond Activation through Hydrogen Bonding to Bridging Water Molecules
P La Manna, C Talotta, G Floresta, M De Rosa, A Soriente, A Rescifina, ...
Angewandte Chemie International Edition 57 (19), 5423-5428, 2018
The hexameric resorcinarene capsule as an artificial enzyme: ruling the regio and stereochemistry of a 1, 3-dipolar cycloaddition between nitrones and unsaturated aldehydes
P La Manna, M De Rosa, C Talotta, C Gaeta, A Soriente, G Floresta, ...
Organic Chemistry Frontiers 5 (5), 827-837, 2018
Development of a Sigma-2 Receptor affinity filter through a Monte Carlo based QSAR analysis
A Rescifina, G Floresta, A Marrazzo, C Parenti, O Prezzavento, G Nastasi, ...
European Journal of Pharmaceutical Sciences 106, 94-101, 2017
Progress in the development of selective heme oxygenase-1 inhibitors and their potential therapeutic application
L Salerno, G Floresta, V Ciaffaglione, D Gentile, F Margani, R Turnaturi, ...
European journal of medicinal chemistry 167, 439-453, 2019
Physicochemical Characterization and Antioxidant Activity Evaluation of Idebenone/Hydroxypropyl-β-Cyclodextrin Inclusion Complex
V Venuti, V Crupi, B Fazio, D Majolino, G Acri, B Testagrossa, ...
Biomolecules 9 (10), 531, 2019
Novel structural insight into inhibitors of heme oxygenase-1 (HO-1) by new imidazole-based compounds: Biochemical and in vitro anticancer activity evaluation
KF Greish, L Salerno, R Al Zahrani, E Amata, MN Modica, G Romeo, ...
Molecules 23 (5), 1209, 2018
Potholing of the hydrophobic heme oxygenase-1 western region for the search of potent and selective imidazole-based inhibitors
L Salerno, E Amata, G Romeo, A Marrazzo, O Prezzavento, G Floresta, ...
European journal of medicinal chemistry 148, 54-62, 2018
Targeting heme Oxygenase-1 with hybrid compounds to overcome Imatinib resistance in chronic myeloid leukemia cell lines
V Sorrenti, V Pittalą, G Romeo, E Amata, M Dichiara, A Marrazzo, ...
European Journal of Medicinal Chemistry 158, 937-950, 2018
Sigma-2 receptor ligands QSAR model dataset
A Rescifina, G Floresta, A Marrazzo, C Parenti, O Prezzavento, G Nastasi, ...
Data in brief 13, 514-535, 2017
Synergic interplay between halogen bonding and hydrogen bonding in the activation of a neutral substrate in a nanoconfined space
P La Manna, M De Rosa, C Talotta, A Rescifina, G Floresta, A Soriente, ...
Angewandte Chemie 132 (2), 821-828, 2020
Hyphenated 3D-QSAR statistical model-scaffold hopping analysis for the identification of potentially potent and selective sigma-2 receptor ligands
G Floresta, A Rescifina, A Marrazzo, M Dichiara, V Pistarą, V Pittalą, ...
European journal of medicinal chemistry 139, 884-891, 2017
γ-Cyclodextrin as a catalyst for the synthesis of 2-methyl-3, 5-diarylisoxazolidines in water
G Floresta, C Talotta, C Gaeta, M De Rosa, U Chiacchio, P Neri, ...
The Journal of organic chemistry 82 (9), 4631-4639, 2017
3D-QSAR assisted identification of FABP4 inhibitors: An effective scaffold hopping analysis/QSAR evaluation
G Floresta, A Cilibrizzi, V Abbate, A Spampinato, C Zagni, A Rescifina
Bioorganic Chemistry 84, 276-284, 2019
Discovery of high-affinity cannabinoid receptors ligands through a 3D-QSAR ushered by scaffold-hopping analysis
G Floresta, O Apirakkan, A Rescifina, V Abbate
Molecules 23 (9), 2183, 2018
Identification of Potentially Potent Heme Oxygenase 1 Inhibitors through 3D‐QSAR Coupled to Scaffold‐Hopping Analysis
G Floresta, E Amata, M Dichiara, A Marrazzo, L Salerno, G Romeo, ...
ChemMedChem 13 (13), 1336-1342, 2018
A structure-and ligand-based virtual screening of a database of “Small” marine natural products for the identification of “Blue” Sigma-2 receptor ligands
G Floresta, E Amata, C Barbaraci, D Gentile, R Turnaturi, A Marrazzo, ...
Marine Drugs 16 (10), 384, 2018
Functionalization of single and multi-walled carbon nanotubes with polypropylene glycol decorated pyrrole for the development of doxorubicin nano-conveyors for cancer drug delivery
C Pennetta, G Floresta, ACE Graziano, V Cardile, L Rubino, M Galimberti, ...
Nanomaterials 10 (6), 1073, 2020
Development of new HO-1 inhibitors by a thorough scaffold-hopping analysis
G Floresta, V Pittala, V Sorrenti, G Romeo, L Salerno, A Rescifina
Bioorganic Chemistry 81, 334-339, 2018
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