The search for potent, small‐molecule HDACIs in cancer treatment: a decade after vorinostat C Zagni, G Floresta, G Monciino, A Rescifina Medicinal research reviews 37 (6), 1373-1428, 2017 | 105 | 2017 |
Adipocyte fatty acid binding protein 4 (FABP4) inhibitors. A comprehensive systematic review G Floresta, V Pistarą, E Amata, M Dichiara, A Marrazzo, O Prezzavento, ... European journal of medicinal chemistry 138, 854-873, 2017 | 77 | 2017 |
Mild Friedel–Crafts Reactions inside a Hexameric Resorcinarene Capsule: C− Cl Bond Activation through Hydrogen Bonding to Bridging Water Molecules P La Manna, C Talotta, G Floresta, M De Rosa, A Soriente, A Rescifina, ... Angewandte Chemie International Edition 57 (19), 5423-5428, 2018 | 69 | 2018 |
The hexameric resorcinarene capsule as an artificial enzyme: ruling the regio and stereochemistry of a 1, 3-dipolar cycloaddition between nitrones and unsaturated aldehydes P La Manna, M De Rosa, C Talotta, C Gaeta, A Soriente, G Floresta, ... Organic Chemistry Frontiers 5 (5), 827-837, 2018 | 51 | 2018 |
Development of a Sigma-2 Receptor affinity filter through a Monte Carlo based QSAR analysis A Rescifina, G Floresta, A Marrazzo, C Parenti, O Prezzavento, G Nastasi, ... European Journal of Pharmaceutical Sciences 106, 94-101, 2017 | 49 | 2017 |
Progress in the development of selective heme oxygenase-1 inhibitors and their potential therapeutic application L Salerno, G Floresta, V Ciaffaglione, D Gentile, F Margani, R Turnaturi, ... European journal of medicinal chemistry 167, 439-453, 2019 | 47 | 2019 |
Physicochemical Characterization and Antioxidant Activity Evaluation of Idebenone/Hydroxypropyl-β-Cyclodextrin Inclusion Complex V Venuti, V Crupi, B Fazio, D Majolino, G Acri, B Testagrossa, ... Biomolecules 9 (10), 531, 2019 | 43 | 2019 |
Novel structural insight into inhibitors of heme oxygenase-1 (HO-1) by new imidazole-based compounds: Biochemical and in vitro anticancer activity evaluation KF Greish, L Salerno, R Al Zahrani, E Amata, MN Modica, G Romeo, ... Molecules 23 (5), 1209, 2018 | 40 | 2018 |
Potholing of the hydrophobic heme oxygenase-1 western region for the search of potent and selective imidazole-based inhibitors L Salerno, E Amata, G Romeo, A Marrazzo, O Prezzavento, G Floresta, ... European journal of medicinal chemistry 148, 54-62, 2018 | 40 | 2018 |
Targeting heme Oxygenase-1 with hybrid compounds to overcome Imatinib resistance in chronic myeloid leukemia cell lines V Sorrenti, V Pittalą, G Romeo, E Amata, M Dichiara, A Marrazzo, ... European Journal of Medicinal Chemistry 158, 937-950, 2018 | 39 | 2018 |
Sigma-2 receptor ligands QSAR model dataset A Rescifina, G Floresta, A Marrazzo, C Parenti, O Prezzavento, G Nastasi, ... Data in brief 13, 514-535, 2017 | 34 | 2017 |
Synergic interplay between halogen bonding and hydrogen bonding in the activation of a neutral substrate in a nanoconfined space P La Manna, M De Rosa, C Talotta, A Rescifina, G Floresta, A Soriente, ... Angewandte Chemie 132 (2), 821-828, 2020 | 32 | 2020 |
Hyphenated 3D-QSAR statistical model-scaffold hopping analysis for the identification of potentially potent and selective sigma-2 receptor ligands G Floresta, A Rescifina, A Marrazzo, M Dichiara, V Pistarą, V Pittalą, ... European journal of medicinal chemistry 139, 884-891, 2017 | 31 | 2017 |
γ-Cyclodextrin as a catalyst for the synthesis of 2-methyl-3, 5-diarylisoxazolidines in water G Floresta, C Talotta, C Gaeta, M De Rosa, U Chiacchio, P Neri, ... The Journal of organic chemistry 82 (9), 4631-4639, 2017 | 31 | 2017 |
3D-QSAR assisted identification of FABP4 inhibitors: An effective scaffold hopping analysis/QSAR evaluation G Floresta, A Cilibrizzi, V Abbate, A Spampinato, C Zagni, A Rescifina Bioorganic Chemistry 84, 276-284, 2019 | 29 | 2019 |
Discovery of high-affinity cannabinoid receptors ligands through a 3D-QSAR ushered by scaffold-hopping analysis G Floresta, O Apirakkan, A Rescifina, V Abbate Molecules 23 (9), 2183, 2018 | 29 | 2018 |
Identification of Potentially Potent Heme Oxygenase 1 Inhibitors through 3D‐QSAR Coupled to Scaffold‐Hopping Analysis G Floresta, E Amata, M Dichiara, A Marrazzo, L Salerno, G Romeo, ... ChemMedChem 13 (13), 1336-1342, 2018 | 28 | 2018 |
A structure-and ligand-based virtual screening of a database of “Small” marine natural products for the identification of “Blue” Sigma-2 receptor ligands G Floresta, E Amata, C Barbaraci, D Gentile, R Turnaturi, A Marrazzo, ... Marine Drugs 16 (10), 384, 2018 | 27 | 2018 |
Functionalization of single and multi-walled carbon nanotubes with polypropylene glycol decorated pyrrole for the development of doxorubicin nano-conveyors for cancer drug delivery C Pennetta, G Floresta, ACE Graziano, V Cardile, L Rubino, M Galimberti, ... Nanomaterials 10 (6), 1073, 2020 | 26 | 2020 |
Development of new HO-1 inhibitors by a thorough scaffold-hopping analysis G Floresta, V Pittala, V Sorrenti, G Romeo, L Salerno, A Rescifina Bioorganic Chemistry 81, 334-339, 2018 | 26 | 2018 |