|When mutants gain new powers: news from the mutant p53 field|
R Brosh, V Rotter
Nature reviews cancer 9 (10), 701-713, 2009
|Mutations in the p53 tumor suppressor gene: important milestones at the various steps of tumorigenesis|
N Rivlin, R Brosh, M Oren, V Rotter
Genes & cancer 2 (4), 466-474, 2011
|Epigenetic polymorphism and the stochastic formation of differentially methylated regions in normal and cancerous tissues|
G Landan, NM Cohen, Z Mukamel, A Bar, A Molchadsky, R Brosh, ...
Nature genetics 44 (11), 1207-1214, 2012
|p53-dependent down-regulation of telomerase is mediated by p21waf1|
I Shats, M Milyavsky, X Tang, P Stambolsky, N Erez, R Brosh, I Kogan, ...
Journal of Biological Chemistry 279 (49), 50976-50985, 2004
|p53‐repressed miRNAs are involved with E2F in a feed‐forward loop promoting proliferation|
R Brosh, R Shalgi, A Liran, G Landan, K Korotayev, GH Nguyen, E Enerly, ...
Molecular systems biology 4 (1), 229, 2008
|p53 is balancing development, differentiation and de-differentiation to assure cancer prevention|
A Molchadsky, N Rivlin, R Brosh, V Rotter, R Sarig
Carcinogenesis 31 (9), 1501-1508, 2010
|Mutant p53 facilitates somatic cell reprogramming and augments the malignant potential of reprogrammed cells|
R Sarig, N Rivlin, R Brosh, C Bornstein, I Kamer, O Ezra, A Molchadsky, ...
Journal of Experimental Medicine 207 (10), 2127-2140, 2010
|TMPRSS2/ERG promotes epithelial to mesenchymal transition through the ZEB1/ZEB2 axis in a prostate cancer model|
O Leshem, S Madar, I Kogan-Sakin, I Kamer, I Goldstein, R Brosh, ...
PloS one 6 (7), e21650, 2011
|Modulated expression of WFDC1 during carcinogenesis and cellular senescence|
S Madar, R Brosh, Y Buganim, O Ezra, I Goldstein, H Solomon, I Kogan, ...
Carcinogenesis 30 (1), 20-27, 2009
|The promoters of human cell cycle genes integrate signals from two tumor suppressive pathways during cellular transformation|
Y Tabach, M Milyavsky, I Shats, R Brosh, O Zuk, A Yitzhaky, R Mantovani, ...
Molecular systems biology 1 (1), 2005.0022, 2005
|p53 Regulates the Ras circuit to inhibit the expression of a cancer-related gene signature by various molecular pathways|
Y Buganim, H Solomon, Y Rais, D Kistner, I Nachmany, M Brait, S Madar, ...
Cancer research 70 (6), 2274-2284, 2010
|Wide-scale analysis of human functional transcription factor binding reveals a strong bias towards the transcription start site|
Y Tabach, R Brosh, Y Buganim, A Reiner, O Zuk, A Yitzhaky, M Koudritsky, ...
PloS one 2 (8), e807, 2007
|Various p53 mutant proteins differently regulate the Ras circuit to induce a cancer-related gene signature|
H Solomon, Y Buganim, I Kogan-Sakin, L Pomeraniec, Y Assia, S Madar, ...
Journal of cell science 125 (13), 3144-3152, 2012
|Prostate stromal cells produce CXCL-1, CXCL-2, CXCL-3 and IL-8 in response to epithelia-secreted IL-1|
I Kogan-Sakin, M Cohen, N Paland, S Madar, H Solomon, A Molchadsky, ...
Carcinogenesis 30 (4), 698-705, 2009
|Inactivation of myocardin and p16 during malignant transformation contributes to a differentiation defect|
M Milyavsky, I Shats, A Cholostoy, R Brosh, Y Buganim, L Weisz, I Kogan, ...
Cancer cell 11 (2), 133-146, 2007
|Coupling transcriptional and post-transcriptional miRNA regulation in the control of cell fate|
R Shalgi, R Brosh, M Oren, Y Pilpel, V Rotter
Aging (Albany NY) 1 (9), 762, 2009
|A novel translocation breakpoint within the BPTF gene is associated with a pre-malignant phenotype|
Y Buganim, I Goldstein, D Lipson, M Milyavsky, S Polak-Charcon, ...
PloS one 5 (3), e9657, 2010
|Structural Basis of Restoring Sequence-Specific DNA Binding and Transactivation to Mutant p53 by Suppressor Mutations☆|
ZS O Suad, H Rozenberg, R Brosh, Y Diskin-Posner, N Kessler, L.J.W Shimon, F ...
J. Mol. Biol 385, 249-265, 2009
|p53 counteracts reprogramming by inhibiting mesenchymal-to-epithelial transition|
R Brosh, Y Assia-Alroy, A Molchadsky, C Bornstein, E Dekel, S Madar, ...
Cell Death & Differentiation 20 (2), 312-320, 2013
|Transcriptional activity of ATF3 in the stromal compartment of tumors promotes cancer progression|
Y Buganim, S Madar, Y Rais, L Pomeraniec, E Harel, H Solomon, E Kalo, ...
Carcinogenesis 32 (12), 1749-1757, 2011