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Brigham Hartley
Brigham Hartley
Principal Scientist, NYSCF
Email verificata su nyscf.org
Titolo
Citata da
Citata da
Anno
An efficient platform for astrocyte differentiation from human induced pluripotent stem cells
TCW Julia, M Wang, AA Pimenova, KR Bowles, BJ Hartley, E Lacin, ...
Stem cell reports 9 (2), 600-614, 2017
3612017
High-content screening in hPSC-neural progenitors identifies drug candidates that inhibit Zika virus infection in fetal-like organoids and adult brain
T Zhou, L Tan, GY Cederquist, Y Fan, BJ Hartley, S Mukherjee, ...
Cell stem cell 21 (2), 274-283. e5, 2017
2352017
Rapid Ngn2-induction of excitatory neurons from hiPSC-derived neural progenitor cells
SM Ho, BJ Hartley, TCW Julia, M Beaumont, K Stafford, PA Slesinger, ...
Methods 101, 113-124, 2016
1542016
Transcriptional signatures of schizophrenia in hiPSC-derived NPCs and neurons are concordant with post-mortem adult brains
GE Hoffman, BJ Hartley, E Flaherty, I Ladran, P Gochman, DM Ruderfer, ...
Nature communications 8 (1), 2225, 2017
1452017
The methyltransferase SETDB1 regulates a large neuron-specific topological chromatin domain
Y Jiang, YHE Loh, P Rajarajan, T Hirayama, W Liao, BS Kassim, ...
Nature genetics 49 (8), 1239-1250, 2017
1452017
Dysregulation of miRNA-9 in a subset of schizophrenia patient-derived neural progenitor cells
A Topol, S Zhu, BJ Hartley, J English, ME Hauberg, N Tran, ...
Cell reports 15 (5), 1024-1036, 2016
1312016
Sex-specific role for the long non-coding RNA LINC00473 in depression
O Issler, YY van der Zee, A Ramakrishnan, J Wang, C Tan, YHE Loh, ...
Neuron 106 (6), 912-926. e5, 2020
1072020
A psychiatric disease-related circular RNA controls synaptic gene expression and cognition
AJ Zimmerman, AK Hafez, SK Amoah, BA Rodriguez, M Dell’Orco, ...
Molecular psychiatry 25 (11), 2712-2727, 2020
1052020
In utero exposure to maternal smoking is associated with DNA methylation alterations and reduced neuronal content in the developing fetal brain
Z Chatterton, BJ Hartley, MH Seok, N Mendelev, S Chen, M Milekic, ...
Epigenetics & chromatin 10, 1-11, 2017
982017
Evaluating synthetic activation and repression of neuropsychiatric-related genes in hiPSC-derived NPCs, neurons, and astrocytes
SM Ho, BJ Hartley, E Flaherty, P Rajarajan, R Abdelaal, I Obiorah, ...
Stem cell reports 9 (2), 615-628, 2017
772017
Expression-based drug screening of neural progenitor cells from individuals with schizophrenia
B Readhead, BJ Hartley, BJ Eastwood, DA Collier, D Evans, R Farias, ...
Nature communications 9 (1), 4412, 2018
762018
Increased abundance of translation machinery in stem cell–derived neural progenitor cells from four schizophrenia patients
A Topol, JA English, E Flaherty, P Rajarajan, BJ Hartley, S Gupta, ...
Translational psychiatry 5 (10), e662-e662, 2015
722015
Characterization of molecular and cellular phenotypes associated with a heterozygous CNTNAP2 deletion using patient-derived hiPSC neural cells
IS Lee, C Carvalho, P Douvaras, SM Ho, BJ Hartley, LW Zuccherato, ...
NPJ schizophrenia 1 (1), 1-5, 2015
602015
Neural organoids for disease phenotyping, drug screening and developmental biology studies
BJ Hartley, KJ Brennand
Neurochemistry international 106, 85-93, 2017
472017
Inhibition of STEP61 ameliorates deficits in mouse and hiPSC-based schizophrenia models
J Xu, BJ Hartley, P Kurup, A Phillips, A Topol, M Xu, C Ononenyi, ...
Molecular psychiatry 23 (2), 271-281, 2018
412018
Lmx1a allows context-specific isolation of progenitors of GABAergic or dopaminergic neurons during neural differentiation of embryonic stem cells
CM Nefzger, CT Su, SA Fabb, BJ Hartley, SJ Beh, WR Zeng, JM Haynes, ...
Stem Cells 30 (7), 1349-1361, 2012
362012
Dopaminergic differentiation of schizophrenia hiPSCs
BJ Hartley, N Tran, I Ladran, K Reggio, KJ Brennand
Molecular psychiatry 20 (5), 549-550, 2015
332015
Resolving the unconventional mechanisms underlying RXFP1 and RXFP2 receptor function
BJ Hartley, DJ Scott, GE Callander, TN Wilkinson, DE Ganella, CK Kong, ...
Annals of the New York Academy of Sciences 1160 (1), 67-73, 2009
302009
Human pluripotent stem cell derived midbrain PITX3eGFP/w neurons: a versatile tool for pharmacological screening and neurodegenerative modeling
B Watmuff, BJ Hartley, CPJ Hunt, SA Fabb, CW Pouton, JM Haynes
Frontiers in cellular neuroscience 9, 104, 2015
232015
A bidirectional competitive interaction between circHomer1 and Homer1b within the orbitofrontal cortex regulates reversal learning
AK Hafez, AJ Zimmerman, G Papageorgiou, J Chandrasekaran, ...
Cell reports 38 (3), 2022
212022
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