| The allosteric regulation of pyruvate kinase: a site-directed mutagenesis study G Valentini, L Chiarelli, R Fortin, ML Speranza, A Galizzi, A Mattevi Journal of Biological Chemistry 275 (24), 18145-18152, 2000 | 209 | 2000 |
| ThermoFAD, a Thermofluor®‐adapted flavin ad hoc detection system for protein folding and ligand binding F Forneris, R Orru, D Bonivento, LR Chiarelli, A Mattevi The FEBS journal 276 (10), 2833-2840, 2009 | 194 | 2009 |
| Structural basis for benzothiazinone-mediated killing of Mycobacterium tuberculosis J Neres, F Pojer, E Molteni, LR Chiarelli, N Dhar, S Boy-Röttger, S Buroni, ... Science translational medicine 4 (150), 150ra121-150ra121, 2012 | 180 | 2012 |
| Pyruvate kinase deficiency: the genotype-phenotype association A Zanella, E Fermo, P Bianchi, LR Chiarelli, G Valentini Blood reviews 21 (4), 217-231, 2007 | 177 | 2007 |
| Structure and function of human erythrocyte pyruvate kinase: molecular basis of nonspherocytic hemolytic anemia G Valentini, LR Chiarelli, R Fortin, M Dolzan, A Galizzi, DJ Abraham, ... Journal of Biological Chemistry 277 (26), 23807-23814, 2002 | 157 | 2002 |
| Burkholderia cenocepacia Infections in Cystic Fibrosis Patients: Drug Resistance and Therapeutic Approaches VC Scoffone, LR Chiarelli, G Trespidi, M Mentasti, G Riccardi, S Buroni Frontiers in microbiology 8, 1592, 2017 | 138 | 2017 |
| Helicobacter pyloril-asparaginase: a promising chemotherapeutic agent D Cappelletti, LR Chiarelli, MV Pasquetto, S Stivala, G Valentini, C Scotti Biochemical and biophysical research communications 377 (4), 1222-1226, 2008 | 115 | 2008 |
| 2-Carboxyquinoxalines Kill Mycobacterium tuberculosis through Noncovalent Inhibition of DprE1 J Neres, RC Hartkoorn, LR Chiarelli, R Gadupudi, MR Pasca, G Mori, ... ACS chemical biology 10 (3), 705-714, 2015 | 107 | 2015 |
| Expanding targets for a metabolic therapy of cancer: L-asparaginase D Covini, S Tardito, O Bussolati, L R Chiarelli, M V Pasquetto, R Digilio, ... Recent patents on anti-cancer drug discovery 7 (1), 4-13, 2012 | 106 | 2012 |
| The DprE1 enzyme, one of the most vulnerable targets of Mycobacterium tuberculosis G Riccardi, MR Pasca, LR Chiarelli, G Manina, A Mattevi, C Binda Applied microbiology and biotechnology 97, 8841-8848, 2013 | 98 | 2013 |
| Biological and structural characterization of the Mycobacterium smegmatis nitroreductase NfnB, and its role in benzothiazinone resistance G Manina, M Bellinzoni, MR Pasca, J Neres, A Milano, ... Molecular microbiology 77 (5), 1172-1185, 2010 | 85 | 2010 |
| 4-Aminoquinolone piperidine amides: noncovalent inhibitors of DprE1 with long residence time and potent antimycobacterial activity M Naik, V Humnabadkar, SJ Tantry, M Panda, A Narayan, S Guptha, ... Journal of medicinal chemistry 57 (12), 5419-5434, 2014 | 84 | 2014 |
| Mycobacterium abscessus, an Emerging and Worrisome Pathogen among Cystic Fibrosis Patients G Degiacomi, JC Sammartino, LR Chiarelli, O Riabova, V Makarov, ... International journal of molecular sciences 20 (23), 5868, 2019 | 76 | 2019 |
| Structure of a lectin with antitumoral properties in king bolete (Boletus edulis) mushrooms M Bovi, ME Carrizo, S Capaldi, M Perduca, LR Chiarelli, M Galliano, ... Glycobiology 21 (8), 1000-1009, 2011 | 75 | 2011 |
| Protein recognition by short peptide reversible inhibitors of the chromatin-modifying LSD1/CoREST lysine demethylase M Tortorici, MT Borrello, M Tardugno, LR Chiarelli, S Pilotto, G Ciossani, ... ACS chemical biology 8 (8), 1677-1682, 2013 | 72 | 2013 |
| Molecular insights on pathogenic effects of mutations causing phosphoglycerate kinase deficiency LR Chiarelli, SM Morera, P Bianchi, E Fermo, A Zanella, A Galizzi, ... PLOS one 7 (2), e32065, 2012 | 71 | 2012 |
| Mechanochemical synthesis and biological evaluation of novel isoniazid derivatives with potent antitubercular activity PFM Oliveira, B Guidetti, A Chamayou, C André-Barrès, J Madacki, ... Molecules 22 (9), 1457, 2017 | 67 | 2017 |
| Thiophenecarboxamide Derivatives Activated by EthA Kill Mycobacterium tuberculosis by Inhibiting the CTP Synthetase PyrG G Mori, LR Chiarelli, M Esposito, V Makarov, M Bellinzoni, RC Hartkoorn, ... Chemistry & biology 22 (7), 917-927, 2015 | 66 | 2015 |
| BEL β-trefoil: A novel lectin with antineoplastic properties in king bolete (Boletus edulis) mushrooms M Bovi, L Cenci, M Perduca, S Capaldi, ME Carrizo, L Civiero, ... Glycobiology 23 (5), 578-592, 2013 | 65 | 2013 |
| Cell-cycle inhibition by Helicobacter pylori L-asparaginase C Scotti, P Sommi, MV Pasquetto, D Cappelletti, S Stivala, P Mignosi, ... PloS one 5 (11), e13892, 2010 | 63 | 2010 |
Giovanna ValentiniAssociated Professor, Department of Biology and Biotechnology, University of PaviaEmail verificata su unipv.it
