Laurent Chiarelli
Laurent Chiarelli
Department of Biology and Biotechnology, University of Pavia
Email verificata su - Home page
Citata da
Citata da
The allosteric regulation of pyruvate kinase A site-directed mutagenesis study
G Valentini, L Chiarelli, R Fortin, ML Speranza, A Galizzi, A Mattevi
Journal of Biological Chemistry 275 (24), 18145-18152, 2000
ThermoFAD, a Thermofluor®‐adapted flavin ad hoc detection system for protein folding and ligand binding
F Forneris, R Orru, D Bonivento, LR Chiarelli, A Mattevi
The FEBS journal 276 (10), 2833-2840, 2009
Pyruvate kinase deficiency: the genotype-phenotype association
A Zanella, E Fermo, P Bianchi, LR Chiarelli, G Valentini
Blood reviews 21 (4), 217-231, 2007
Structure and function of human erythrocyte pyruvate kinase Molecular basis of nonspherocytic hemolytic anemia
G Valentini, LR Chiarelli, R Fortin, M Dolzan, A Galizzi, DJ Abraham, ...
Journal of Biological Chemistry 277 (26), 23807-23814, 2002
Structural basis for benzothiazinone-mediated killing of Mycobacterium tuberculosis
J Neres, F Pojer, E Molteni, LR Chiarelli, N Dhar, S Boy-Röttger, S Buroni, ...
Science translational medicine 4 (150), 150ra121-150ra121, 2012
Helicobacter pyloril-asparaginase: a promising chemotherapeutic agent
D Cappelletti, LR Chiarelli, MV Pasquetto, S Stivala, G Valentini, C Scotti
Biochemical and biophysical research communications 377 (4), 1222-1226, 2008
2-Carboxyquinoxalines Kill Mycobacterium tuberculosis through Noncovalent Inhibition of DprE1
J Neres, RC Hartkoorn, LR Chiarelli, R Gadupudi, MR Pasca, G Mori, ...
ACS chemical biology 10 (3), 705-714, 2015
Biological and structural characterization of the Mycobacterium smegmatis nitroreductase NfnB, and its role in benzothiazinone resistance
G Manina, M Bellinzoni, MR Pasca, J Neres, A Milano, ...
Molecular microbiology 77 (5), 1172-1185, 2010
The DprE1 enzyme, one of the most vulnerable targets of Mycobacterium tuberculosis
G Riccardi, MR Pasca, LR Chiarelli, G Manina, A Mattevi, C Binda
Applied microbiology and biotechnology 97 (20), 8841-8848, 2013
4-aminoquinolone piperidine amides: noncovalent inhibitors of DprE1 with long residence time and potent antimycobacterial activity
M Naik, V Humnabadkar, SJ Tantry, M Panda, A Narayan, S Guptha, ...
Journal of medicinal chemistry 57 (12), 5419-5434, 2014
Expanding targets for a metabolic therapy of cancer: L-asparaginase
D Covini, S Tardito, O Bussolati, L R Chiarelli, M V Pasquetto, R Digilio, ...
Recent Patents on Anti-Cancer Drug Discovery 7 (1), 4-13, 2012
Structure of a lectin with antitumoral properties in king bolete (Boletus edulis) mushrooms
M Bovi, ME Carrizo, S Capaldi, M Perduca, LR Chiarelli, M Galliano, ...
Glycobiology 21 (8), 1000-1009, 2011
Analogous mechanisms of resistance to benzothiazinones and dinitrobenzamides in Mycobacterium smegmatis
ALJL Ribeiro, G Degiacomi, F Ewann, S Buroni, ML Incandela, ...
PloS one 6 (11), e26675, 2011
Human erythrocyte pyruvate kinase: characterization of the recombinant enzyme and a mutant form (R510Q) causing nonspherocytic hemolytic anemia
C Wang, LR Chiarelli, P Bianchi, DJ Abraham, A Galizzi, A Mattevi, ...
Blood, The Journal of the American Society of Hematology 98 (10), 3113-3120, 2001
Protein recognition by short peptide reversible inhibitors of the chromatin-modifying LSD1/CoREST lysine demethylase
M Tortorici, MT Borrello, M Tardugno, LR Chiarelli, S Pilotto, G Ciossani, ...
ACS chemical biology 8 (8), 1677-1682, 2013
Cell-cycle inhibition by Helicobacter pylori L-asparaginase
C Scotti, P Sommi, MV Pasquetto, D Cappelletti, S Stivala, P Mignosi, ...
PloS one 5 (11), e13892, 2010
Burkholderia cenocepacia infections in cystic fibrosis patients: drug resistance and therapeutic approaches
VC Scoffone, LR Chiarelli, G Trespidi, M Mentasti, G Riccardi, S Buroni
Frontiers in microbiology 8, 1592, 2017
Molecular insights on pathogenic effects of mutations causing phosphoglycerate kinase deficiency
LR Chiarelli, SM Morera, P Bianchi, E Fermo, A Zanella, A Galizzi, ...
PLOS one 7 (2), e32065, 2012
Inosine monophosphate dehydrogenase variability in renal transplant patients on long‐term mycophenolate mofetil therapy
LR Chiarelli, M Molinaro, C Libetta, C Tinelli, L Cosmai, G Valentini, ...
British journal of clinical pharmacology 69 (1), 38-50, 2010
BEL β-trefoil: A novel lectin with antineoplastic properties in king bolete (Boletus edulis) mushrooms
M Bovi, L Cenci, M Perduca, S Capaldi, ME Carrizo, L Civiero, ...
Glycobiology 23 (5), 578-592, 2013
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