Benedetta Gualeni
Benedetta Gualeni
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A diastrophic dysplasia sulfate transporter (SLC26A2) mutant mouse: morphological and biochemical characterization of the resulting chondrodysplasia phenotype
A Forlino, R Piazza, C Tiveron, SD Torre, L Tatangelo, L Bonafe, ...
Human molecular genetics 14 (6), 859-871, 2005
A novel form of chondrocyte stress is triggered by a COMP mutation causing pseudoachondroplasia
F Suleman, B Gualeni, HJ Gregson, MP Leighton, KA Piróg, S Edwards, ...
Human mutation 33 (1), 218-231, 2012
Differential expression of both extracellular and intracellular proteins is involved in the lethal or nonlethal phenotypic variation of BrtlIV, a murine model for osteogenesis …
A Forlino, C Tani, A Rossi, A Lupi, E Campari, B Gualeni, L Bianchi, ...
Proteomics 7 (11), 1877-1891, 2007
Defective proteoglycan sulfation of the growth plate zones causes reduced chondrocyte proliferation via an altered Indian hedgehog signalling
B Gualeni, M Facchini, F De Leonardis, R Tenni, G Cetta, M Viola, A Passi, ...
Matrix Biology 29 (6), 453-460, 2010
Alteration of proteoglycan sulfation affects bone growth and remodeling
B Gualeni, MC de Vernejoul, C Marty-Morieux, F De Leonardis, M Franchi, ...
Bone 54 (1), 83-91, 2013
Minimally invasive and targeted therapeutic cell delivery to the skin using microneedle devices
B Gualeni, SA Coulman, D Shah, PF Eng, H Ashraf, P Vescovo, ...
British Journal of Dermatology 178 (3), 731-739, 2018
Matrix disruptions, growth, and degradation of cartilage with impaired sulfation
EL Mertz, M Facchini, AT Pham, B Gualeni, F De Leonardis, A Rossi, ...
Journal of Biological Chemistry 287 (26), 22030-22042, 2012
A quantitative and qualitative method for direct 2‐DE analysis of murine cartilage
F Pecora, A Forlino, B Gualeni, A Lupi, S Giorgetti, L Marchese, ...
Proteomics 7 (21), 4003-4007, 2007
In vivo contribution of amino acid sulfur to cartilage proteoglycan sulfation
F Pecora, B Gualeni, A Forlino, A Superti-Furga, R Tenni, G Cetta, A Rossi
Biochemical Journal 398 (3), 509-514, 2006
A novel transgenic mouse model of growth plate dysplasia reveals that decreased chondrocyte proliferation due to chronic ER stress is a key factor in reduced bone growth
B Gualeni, MH Rajpar, A Kellogg, PA Bell, P Arvan, RP Boot-Handford, ...
Disease models & mechanisms 6 (6), 1414-1425, 2013
Hollow silicon microneedle fabrication using advanced plasma etch technologies for applications in transdermal drug delivery
CJW Bolton, O Howells, GJ Blayney, PF Eng, JC Birchall, B Gualeni, ...
Lab on a Chip 20 (15), 2788-2795, 2020
Altered signaling in the G1 phase deregulates chondrocyte growth in a mouse model with proteoglycan undersulfation
FD Leonardis, L Monti, B Gualeni, R Tenni, A Forlino, A Rossi
Journal of cellular biochemistry 115 (10), 1779-1786, 2014
Insights from a transgenic mouse model on the role of SLC26A2 in health and disease
A Forlino, B Gualeni, F Pecora, SD Torre, R Piazza, C Tiveron, ...
Novartis Foundation symposium 273, 193, 2006
Human-centred design of a new microneedle-based hormonal contraceptive delivery system
B Gualeni, L Hughes, I Stauber, L Ackers, A Gorman, D Gashuga, ...
Gates Open Research 5, 96, 2021
Microneedle based cell delivery
J Birchall, S Coulman, S Dev, B Gualeni
US Patent 10,232,159, 2019
Morphological and biochemical characterization of bone phenotype in a chondrodysplasia mouse model
B Gualeni, A Rossi, V Geoffrey, C Marty-Morieux, A Forlino, F Pecora, ...
Models and methods to characterise levonorgestrel release from intradermally administered contraceptives
A Al Dalaty, B Gualeni, SA Coulman, JC Birchall
Drug delivery and translational research 12 (2), 335-349, 2022
Design, fabrication, and characterisation of a silicon microneedle array for transdermal therapeutic delivery using a single step wet etch process
O Howells, GJ Blayney, B Gualeni, JC Birchall, PF Eng, H Ashraf, ...
European Journal of Pharmaceutics and Biopharmaceutics 171, 19-28, 2022
2 approved with reservations
B Gualeni, L Hughes, I Stauber, L Ackers, A Gorman, D Gashuga, ...
Gates Open Research
B Gualeni, L Hughes, I Stauber, L Ackers, A Gorman, D Gashuga, ...
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