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Filippo Severin
Titolo
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Anno
Direct pharmacological targeting of a mitochondrial ion channel selectively kills tumor cells in vivo
L Leanza, M Romio, KA Becker, M Azzolini, L Trentin, A Manago, ...
Cancer cell 31 (4), 516-531. e10, 2017
1492017
Cross-talk between chronic lymphocytic leukemia (CLL) tumor B cells and mesenchymal stromal cells (MSCs): implications for neoplastic cell survival
V Trimarco, E Ave, M Facco, G Chiodin, F Frezzato, V Martini, C Gattazzo, ...
Oncotarget 6 (39), 42130, 2015
532015
In chronic lymphocytic leukemia the JAK2/STAT3 pathway is constitutively activated and its inhibition leads to CLL cell death unaffected by the protective bone marrow …
F Severin, F Frezzato, A Visentin, V Martini, V Trimarco, S Carraro, ...
Cancers 11 (12), 1939, 2019
472019
HSP70/HSF1 axis, regulated via a PI3K/AKT pathway, is a druggable target in chronic lymphocytic leukemia
F Frezzato, F Raggi, V Martini, F Severin, V Trimarco, A Visentin, ...
International journal of cancer 145 (11), 3089-3100, 2019
412019
Cortactin, a Lyn substrate, is a checkpoint molecule at the intersection of BCR and CXCR4 signalling pathway in chronic lymphocytic leukaemia cells
V Martini, C Gattazzo, F Frezzato, V Trimarco, M Pizzi, G Chiodin, ...
British journal of haematology 178 (1), 81-93, 2017
372017
Integrated CLL scoring system, a new and simple index to predict time to treatment and overall survival in patients with chronic lymphocytic leukemia
A Visentin, M Facco, F Frezzato, M Castelli, V Trimarco, V Martini, ...
Clinical Lymphoma Myeloma and Leukemia 15 (10), 612-620. e5, 2015
362015
Prognostic and predictive effect of IGHV mutational status and load in chronic lymphocytic leukemia: focus on FCR and BR treatments
A Visentin, M Facco, C Gurrieri, E Pagnin, V Martini, S Imbergamo, ...
Clinical Lymphoma Myeloma and Leukemia 19 (10), 678-685. e4, 2019
332019
Major infections, secondary cancers and autoimmune diseases occur in different clinical subsets of chronic lymphocytic leukaemia patients
A Visentin, S Imbergamo, C Gurrieri, F Frezzato, V Trimarco, V Martini, ...
European Journal of Cancer 72, 103-111, 2017
312017
Lights and shade of next-generation Pi3k inhibitors in chronic lymphocytic leukemia
A Visentin, F Frezzato, F Severin, S Imbergamo, S Pravato, ...
OncoTargets and therapy, 9679-9688, 2020
212020
Profiling B cell chronic lymphocytic leukemia by reverse phase protein array: Focus on apoptotic proteins
F Frezzato, B Accordi, V Trimarco, C Gattazzo, V Martini, G Milani, ...
Journal of Leucocyte Biology 100 (5), 1061-1070, 2016
202016
Pharmacological modulation of Kv1. 3 potassium channel selectively triggers pathological B lymphocyte apoptosis in vivo in a genetic CLL model
F Severin, A Urbani, T Varanita, M Bachmann, M Azzolini, V Martini, ...
Journal of Experimental & Clinical Cancer Research 41 (1), 64, 2022
152022
Abnormal regulation of BCR signalling by c-Cbl in chronic lymphocytic leukaemia
V Martini, F Frezzato, F Severin, F Raggi, V Trimarco, L Martinello, ...
Oncotarget 9 (63), 32219, 2018
92018
Targeting of HSP70/HSF1 axis abrogates in vitro ibrutinib-resistance in chronic lymphocytic leukemia
F Frezzato, A Visentin, F Severin, S Pizzo, E Ruggeri, N Mouawad, ...
Cancers 13 (21), 5453, 2021
82021
Is It Still Possible to Think about HSP70 as a Therapeutic Target in Onco-Hematological Diseases?
N Mouawad, G Capasso, E Ruggeri, L Martinello, F Severin, A Visentin, ...
Biomolecules 13 (4), 604, 2023
62023
Targeting Brutons Tyrosine Kinase in Chronic Lymphocytic Leukemia at the Crossroad between Intrinsic and Extrinsic Pro-survival Signals
F Frezzato, V Trimarco, A Visentin, V Martini, F Severin, M Facco, ...
JOURNAL OF LEUKEMIA 4 (01), 207-215, 2016
52016
Protective role immunoglobulin replacement therapy in chronic lymphocytic leukemia: FOCUS on subcutaneous immunoglobulin formulations
A Visentin, FR Mauro, S Rosati, S Imbergamo, E Scomazzon, S Pravato, ...
Blood 132, 4954, 2018
42018
Focal adhesion kinase activation by calcium‐dependent calpain is involved in chronic lymphocytic leukaemia cell aggressiveness
F Severin, N Mouawad, E Ruggeri, A Visentin, L Martinello, E Pagnin, ...
British Journal of Haematology 203 (2), 224-236, 2023
22023
Biology and Microenvironment
A Visentin, F Frezzato, F Severin, M Pizzi, V Martini, F Raggi, ...
22018
Evaluation of Integrated CLL Scoring System (ICSS) in 420 Patients with Chronic Lymphocytic Leukemia
A Visentin, F Frezzato, S Imbergamo, V Trimarco, V Martini, F Severin, ...
Blood 128 (22), 5563, 2016
22016
Inhibition of JAK2/STAT3 pathway leads to apoptosis in chronic lymphocytic leukemia cells
F Severin, F Frezzato, V Martini, F Raggi, V Trimarco, L Martinello, ...
Blood, The Journal of the American Society of Hematology 128 (22), 2023-2023, 2016
22016
Il sistema al momento non può eseguire l'operazione. Riprova più tardi.
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