Michael E. Johnson
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A noncovalent class of papain-like protease/deubiquitinase inhibitors blocks SARS virus replication
K Ratia, S Pegan, J Takayama, K Sleeman, M Coughlin, S Baliji, ...
Proceedings of the National Academy of Sciences 105 (42), 16119-16124, 2008
Multiple novel inhibitors of the NorA multidrug transporter of Staphylococcus aureus
PN Markham, E Westhaus, K Klyachko, ME Johnson, AA Neyfakh
Antimicrobial agents and chemotherapy 43 (10), 2404-2408, 1999
Hit identification and optimization in virtual screening: Practical recommendations based on a critical literature analysis: Miniperspective
T Zhu, S Cao, PC Su, R Patel, D Shah, HB Chokshi, R Szukala, ...
Journal of medicinal chemistry 56 (17), 6560-6572, 2013
Design and synthesis of peptidomimetic severe acute respiratory syndrome chymotrypsin-like protease inhibitors
AK Ghosh, K Xi, K Ratia, BD Santarsiero, W Fu, BH Harcourt, PA Rota, ...
Journal of medicinal chemistry 48 (22), 6767-6771, 2005
Polyoxypregnanes from Marsdenia tenacissima
L Si-Qi, L Long-Ze, GA Cordell, X Liang, ME Johnson
Phytochemistry 34 (6), 1615-1620, 1993
Design and synthesis of a CD4 beta-turn mimetic that inhibits human immunodeficiency virus envelope glycoprotein gp120 binding and infection of human lymphocytes
S Chen, RA Chrusciel, H Nakanishi, A Raktabutr, ME Johnson, A Sato, ...
Proceedings of the National Academy of Sciences 89 (13), 5872-5876, 1992
Severe acute respiratory syndrome coronavirus papain-like novel protease inhibitors: design, synthesis, protein− ligand X-ray structure and biological evaluation
AK Ghosh, J Takayama, KV Rao, K Ratia, R Chaudhuri, DC Mulhearn, ...
Journal of medicinal chemistry 53 (13), 4968-4979, 2010
Cytotoxic and antimalarial bisbenzylisoquinoline alkaloids from Cyclea barbata
LZ Lin, HL Shieh, CK Angerhofer, JM Pezzuto, GA Cordell, L Xue, ...
Journal of natural products 56 (1), 22-29, 1993
[d-Trp32] neuropeptide Y: a competitive antagonist of NPY in rat hypothalamus
A Balasubramaniam, S Sheriff, ME Johnson, M Prabhakaran, Y Huang, ...
Journal of medicinal chemistry 37 (6), 811-815, 1994
Ligand efficiency indices for an effective mapping of chemico-biological space: the concept of an atlas-like representation
C Abad-Zapatero, O Perišić, J Wass, AP Bento, J Overington, ...
Drug discovery today 15 (19-20), 804-811, 2010
Structure-based design, synthesis, and biological evaluation of a series of novel and reversible inhibitors for the severe acute respiratory syndrome− coronavirus papain-like …
AK Ghosh, J Takayama, Y Aubin, K Ratia, R Chaudhuri, Y Baez, ...
Journal of medicinal chemistry 52 (16), 5228-5240, 2009
Identification of novel small molecule inhibitors against NS2B/NS3 serine protease from Zika virus
H Lee, J Ren, S Nocadello, AJ Rice, I Ojeda, S Light, G Minasov, J Vargas, ...
Antiviral research 139, 49-58, 2017
Design, synthesis and antiviral efficacy of a series of potent chloropyridyl ester-derived SARS-CoV 3CLpro inhibitors
AK Ghosh, G Gong, V Grum-Tokars, DC Mulhearn, SC Baker, M Coughlin, ...
Bioorganic & medicinal chemistry letters 18 (20), 5684-5688, 2008
Inhibitor recognition specificity of MERS-CoV papain-like protease may differ from that of SARS-CoV
H Lee, H Lei, BD Santarsiero, JL Gatuz, S Cao, AJ Rice, K Patel, ...
ACS chemical biology 10 (6), 1456-1465, 2015
Structure-based design, synthesis, and biological evaluation of peptidomimetic SARS-CoV 3CLpro inhibitors
AK Ghosh, K Xi, V Grum-Tokars, X Xu, K Ratia, W Fu, KV Houser, ...
Bioorganic & medicinal chemistry letters 17 (21), 5876-5880, 2007
Inhibition of MptpB phosphatase from Mycobacterium tuberculosis impairs mycobacterial survival in macrophages
NJ Beresford, D Mulhearn, B Szczepankiewicz, G Liu, ME Johnson, ...
Journal of antimicrobial chemotherapy 63 (5), 928-936, 2009
Comparison of radii sets, entropy, QM methods, and sampling on MM‐PBSA, MM‐GBSA, and QM/MM‐GBSA ligand binding energies of F. tularensis enoyl‐ACP …
PC Su, CC Tsai, S Mehboob, KE Hevener, ME Johnson
Journal of computational chemistry 36 (25), 1859-1873, 2015
Effects of ligands and organic phosphates on functional properties of human adult hemoglobin
ME Johnson, C Ho
Biochemistry 13 (18), 3653-3661, 1974
Discovery of a novel and potent class of F. tularensis enoyl-reductase (FabI) inhibitors by molecular shape and electrostatic matching
KE Hevener, S Mehboob, PC Su, K Truong, T Boci, J Deng, M Ghassemi, ...
Journal of medicinal chemistry 55 (1), 268-279, 2012
Proposed cation‐π mediated binding by factor Xa: a novel enzymatic mechanism for molecular recognition
Z Lin, ME Johnson
FEBS letters 370 (1-2), 1-5, 1995
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