Dirk Drasdo
Dirk Drasdo
INRIA OR Max-Planck OR IZBI OR IFADO OR IMISE OR Warwick OR University of Goettingen OR RWTH Aachen
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Recent advances in 2D and 3D in vitro systems using primary hepatocytes, alternative hepatocyte sources and non-parenchymal liver cells and their use in investigating …
P Godoy, NJ Hewitt, U Albrecht, ME Andersen, N Ansari, S Bhattacharya, ...
Archives of toxicology 87 (8), 1315-1530, 2013
A single-cell-based model of tumor growth in vitro: monolayers and spheroids
D Drasdo, S Höhme
Physical biology 2 (3), 133, 2005
Prediction and validation of cell alignment along microvessels as order principle to restore tissue architecture in liver regeneration
S Hoehme, M Brulport, A Bauer, E Bedawy, W Schormann, M Hermes, ...
Proceedings of the National Academy of Sciences 107 (23), 10371-10376, 2010
Individual-based and continuum models of growing cell populations: a comparison
H Byrne, D Drasdo
Journal of mathematical biology 58 (4), 657-687, 2009
Modeling the effect of deregulated proliferation and apoptosis on the growth dynamics of epithelial cell populations in vitro
J Galle, M Loeffler, D Drasdo
Biophysical journal 88 (1), 62-75, 2005
Modeling the influence of the E-cadherin-β-catenin pathway in cancer cell invasion: a multiscale approach
I Ramis-Conde, D Drasdo, ARA Anderson, MAJ Chaplain
Biophysical journal 95 (1), 155-165, 2008
Adverse outcome pathways: opportunities, limitations and open questions
M Leist, A Ghallab, R Graepel, R Marchan, R Hassan, SH Bennekou, ...
Archives of toxicology 91 (11), 3477-3505, 2017
Monte Carlo approach to tissue-cell populations
D Drasdo, R Kree, JS McCaskill
Physical review E 52 (6), 6635, 1995
Simulating tissue mechanics with agent-based models: concepts, perspectives and some novel results
P Van Liedekerke, MM Palm, N Jagiella, D Drasdo
Computational particle mechanics 2 (4), 401-444, 2015
On the role of physics in the growth and pattern formation of multi-cellular systems: what can we learn from individual-cell based models?
D Drasdo, S Hoehme, M Block
Journal of Statistical Physics 128 (1), 287-345, 2007
Multi-scale modelling of cancer cell intravasation: the role of cadherins in metastasis
I Ramis-Conde, MAJ Chaplain, ARA Anderson, D Drasdo
Physical biology 6 (1), 016008, 2009
Individual-based approaches to birth and death in avascu1ar tumors
D Drasdo, S Höhme
Mathematical and Computer Modelling 37 (11), 1163-1175, 2003
A cell-based simulation software for multi-cellular systems
S Hoehme, D Drasdo
Bioinformatics 26 (20), 2641-2642, 2010
Protocols for staining of bile canalicular and sinusoidal networks of human, mouse and pig livers, three-dimensional reconstruction and quantification of tissue …
S Hammad, S Hoehme, A Friebel, I Von Recklinghausen, A Othman, ...
Archives of toxicology 88 (5), 1161-1183, 2014
Individual-based models to growth and folding in one-layered tissues: intestinal crypts and early development
D Drasdo, M Loeffler
Nonlinear Analysis: Theory, Methods & Applications 47 (1), 245-256, 2001
Buckling instabilities of one-layered growing tissues
D Drasdo
Physical review letters 84 (18), 4244, 2000
Model-guided identification of a therapeutic strategy to reduce hyperammonemia in liver diseases
A Ghallab, G Cellière, SG Henkel, D Driesch, S Hoehme, U Hofmann, ...
Journal of hepatology 64 (4), 860-871, 2016
Impact of oxygen environment on mesenchymal stem cell expansion and chondrogenic differentiation
A Krinner, M Zscharnack, A Bader, D Drasdo, J Galle
Cell proliferation 42 (4), 471-484, 2009
The virtual liver: a multidisciplinary, multilevel challenge for systems biology
HG Holzhütter, D Drasdo, T Preusser, J Lippert, AM Henney
Wiley Interdisciplinary Reviews: Systems Biology and Medicine 4 (3), 221-235, 2012
Modeling the interplay of generic and genetic mechanisms in cleavage, blastulation, and gastrulation
D Drasdo, G Forgacs
Developmental dynamics: an official publication of the American Association …, 2000
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