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Review of the pharmacokinetics and metabolism of reboxetine, a selective noradrenaline reuptake inhibitor P Dostert, MS Benedetti, I Poggesi European Neuropsychopharmacology 7 (1), S23-S35, 1997 | 181 | 1997 |
Physiologically based pharmacokinetics (PBPK) P Espié, D Tytgat, ML Sargentini-Maier, I Poggesi, JB Watelet Drug metabolism reviews 41 (3), 391-407, 2009 | 159 | 2009 |
Drug metabolism and pharmacokinetics MS Benedetti, R Whomsley, I Poggesi, W Cawello, FX Mathy, ML Delporte, ... Drug metabolism reviews 41 (3), 344-390, 2009 | 157 | 2009 |
Computational models for identifying potential P-glycoprotein substrates and inhibitors P Crivori, B Reinach, D Pezzetta, I Poggesi Molecular pharmaceutics 3 (1), 33-44, 2006 | 150 | 2006 |
Predicting the active doses in humans from animal studies: a novel approach in oncology M Rocchetti, M Simeoni, E Pesenti, G De Nicolao, I Poggesi European journal of cancer 43 (12), 1862-1868, 2007 | 114 | 2007 |
A mathematical model to study the effects of drugs administration on tumor growth dynamics P Magni, M Simeoni, I Poggesi, M Rocchetti, G De Nicolao Mathematical biosciences 200 (2), 127-151, 2006 | 109 | 2006 |
Child–Pugh Classification: Time to Abandon? B Kok, JG Abraldes Seminars in liver disease 39 (01), 096-103, 2019 | 106 | 2019 |
Computational approaches for predicting CYP-related metabolism properties in the screening of new drugs P Crivori, I Poggesi European journal of medicinal chemistry 41 (7), 795-808, 2006 | 98 | 2006 |
Physiologically‐based pharmacokinetic modeling in renal and hepatic impairment populations: a pharmaceutical industry perspective T Heimbach, Y Chen, J Chen, V Dixit, N Parrott, SA Peters, I Poggesi, ... Clinical Pharmacology & Therapeutics 110 (2), 297-310, 2021 | 91 | 2021 |
Population pharmacokinetic model of ibrutinib, a Bruton tyrosine kinase inhibitor, in patients with B cell malignancies E Marostica, J Sukbuntherng, D Loury, J De Jong, XW De Trixhe, ... Cancer chemotherapy and pharmacology 75, 111-121, 2015 | 88 | 2015 |
First Cdc7 kinase inhibitors: pyrrolopyridinones as potent and orally active antitumor agents. 2. Lead discovery M Menichincheri, A Bargiotti, J Berthelsen, JA Bertrand, R Bossi, ... Journal of medicinal chemistry 52 (2), 293-307, 2009 | 85 | 2009 |
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Correlation between prostate-specific antigen kinetics and overall survival in abiraterone acetate–treated castration-resistant prostate cancer patients XS Xu, CJ Ryan, K Stuyckens, MR Smith, F Saad, TW Griffin, YC Park, ... Clinical Cancer Research 21 (14), 3170-3177, 2015 | 77 | 2015 |
Model based on GRID-derived descriptors for estimating CYP3A4 enzyme stability of potential drug candidates P Crivori, I Zamora, B Speed, C Orrenius, I Poggesi Journal of computer-aided molecular design 18, 155-166, 2004 | 69 | 2004 |
Absolute bioavailability of reboxetine enantiomers and effect of gender on pharmacokinetics JC Fleishaker, M Mucci, C Pellizzoni, I Poggesi Biopharmaceutics & drug disposition 20 (1), 53-57, 1999 | 67 | 1999 |
Low environmental radiation background impairs biological defence of the yeast Saccharomyces cerevisiae to chemical radiomimetic agents L Satta, G Augusti-Tocco, R Ceccarelli, A Esposito, M Fiore, P Paggi, ... Mutation Research Letters 347 (3-4), 129-133, 1995 | 66 | 1995 |
Population pharmacokinetic analysis of abiraterone in chemotherapy-naïve and docetaxel-treated patients with metastatic castration-resistant prostate cancer K Stuyckens, F Saad, XS Xu, CJ Ryan, MR Smith, TW Griffin, MK Yu, ... Clinical pharmacokinetics 53, 1149-1160, 2014 | 57 | 2014 |
A predictive model for exemestane pharmacokinetics/pharmacodynamics incorporating the effect of food and formulation M Valle, E Di Salle, MG Jannuzzo, I Poggesi, M Rocchetti, R Spinelli, ... British journal of clinical pharmacology 59 (3), 355-364, 2005 | 54 | 2005 |