Scott Howard Altern

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Steven M. CramerInstitute Professor, Rensselaer Polytechnic InstituteVerified email at rpi.edu
Andrew J KocotPhD student, Rensselaer Polytechnic InstituteVerified email at rpi.edu
Sushmita S. KoleyStaff ScientistVerified email at bio-rad.com
Mayank VatsSr. Scientist, Merck & Co.Verified email at merck.com
Xuan HanAmgenVerified email at amgen.com
Camille BilodeauAssistant ProfessorVerified email at virginia.edu
John WelshPrincipal Consultant, Rivanna Bioprocess Solutions LLCVerified email at rivannabioprocess.com
Vijesh KumarUniversity of Delaware, USAVerified email at udel.edu
AM LenhoffUniversity of DelawareVerified email at udel.edu
Sean BurgessGenentechVerified email at gene.com
Jacob P. LeBarreNorth Carolina State UniversityVerified email at ncsu.edu
Cristiana BoiUniversity of BolognaVerified email at unibo.it
Stefano MenegattiNorth Carolina State UniversityVerified email at ncsu.edu
Dipendra BhandariPhD Student, Department of Physics, Oklahoma State UniversityVerified email at okstate.edu
Ruben G CarbonellProfessor, Chemical and Biomolecular Engineering, NC State UniversityVerified email at ncsu.edu
Eduardo BarbieriResearch AssistantVerified email at ncsu.edu
Wenning ChuPost-doctor, North Carolina State UniversityVerified email at ncsu.edu
Nicholas A VecchiarelloUVA

Scott Howard Altern

AbbVie Bioresearch Center

Verified email at abbvie.com - Homepage

Bioprocessing Chromatography Process Modeling High-throughput Screening Adsorption


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Evaluation of guanidine-based multimodal anion exchangers for protein selectivity and orthogonality S Koley, SH Altern, M Vats, X Han, D Jang, MA Snyder, C Belisle, ... Journal of Chromatography A 1653, 462398, 2021	8	2021
Isotherm model discrimination for multimodal chromatography using mechanistic models derived from high-throughput batch isotherm data SH Altern, JP Welsh, JY Lyall, AJ Kocot, S Burgess, V Kumar, C Williams, ... Journal of Chromatography A, 463878, 2023	7	2023
Quantifying orthogonality and separability: A method for optimizing resin selection and design CL Bilodeau, NA Vecchiarello, S Altern, SM Cramer Journal of Chromatography A 1628, 461429, 2020	7	2020
Mechanistic model-based characterization of size-exclusion-mixed-mode resins for removal of monoclonal antibody fragments SH Altern, AJ Kocot, JP LeBarre, C Boi, MW Phillips, DJ Roush, ... Journal of Chromatography A, 464717, 2024	1	2024
Mechanistic modeling of multimodal chromatography: from first-principles to principal applications SH Altern Rensselaer Polytechnic Institute, 2023	1	2023
Mixed-mode size-exclusion silica resin for polishing human antibodies in flow-through mode JP LeBarre, W Chu, SH Altern, AJ Kocot, D Bhandari, E Barbieri, J Sly, ... Journal of Chromatography A 1720, 464772, 2024		2024
High-throughput In Silico (HT-IS) Workflows for Mechanistic Modeling of Preparative Multimodal Chromatographic Processes SMC Scott H. Altern, Jessica Y. Lyall, John P. Welsh, Andrew J. Kocot ... ACS BIOT 2023, 2023		2023
Isotherm Model Discrimination for Multimodal Chromatography Using Mechanistic Models Derived From High-throughput Batch Isotherm Data SH Altern, J Lyall, JP Welsh, A Kocot, C Williams, AM Lenhoff, SM Cramer PREP 2022, 2022		2022
Optimization and characterization of multimodal chromatographic processes using mechanistic models derived from high-throughput batch isotherm data SH Altern, JY Lyall, C Williams, JP Welsh, J Peyser, V Kumar, AM Lenhoff, ... ACS BIOT 2021, 2021		2021
Bridging high-throughput screening and mechanistic modeling for the development of multimodal chromatographic processes SH Altern, J Yang, C Williams, JP Welsh, J Klockowski, J Peyser, V Kumar, ... ACS BIOT 2020, 2020		2020
Quantifying Orthogonality for Sets of Commercial Resins Using a Mathematical Framework SH Altern, NA Vecchiarello, CL Bilodeau, SM Cramer PREP 2019, 2019		2019

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