Zinc-induced cortical neuronal death: contribution of energy failure attributable to loss of NAD+ and inhibition of glycolysis CT Sheline, MM Behrens, DW Choi Journal of Neuroscience 20 (9), 3139-3146, 2000 | 429 | 2000 |
Activation of the HIV-1 enhancer by the LEF-1 HMG protein on nucleosome-assembled DNA in vitro. PL Sheridan, CT Sheline, K Cannon, ML Voz, MJ Pazin, JT Kadonaga, ... Genes & Development 9 (17), 2090-2104, 1995 | 205 | 1995 |
Two distinct nuclear transcription factors recognize loop and bulge residues of the HIV-1 TAR RNA hairpin. CT Sheline, LH Milocco, KA Jones Genes & development 5 (12b), 2508-2520, 1991 | 183 | 1991 |
Apoptotic insults impair Na+, K+-ATPase activity as a mechanism of neuronal death mediated by concurrent ATP deficiency and oxidant stress XQ Wang, AY Xiao, C Sheline, K Hyrc, A Yang, MP Goldberg, DW Choi, ... Journal of cell science 116 (10), 2099-2110, 2003 | 176 | 2003 |
Localization of a type II DNA topoisomerase to two sites at the periphery of the kinetoplast DNA of Crithidia fasciculata T Melendy, C Sheline, DS Ray Cell 55 (6), 1083-1088, 1988 | 176 | 1988 |
Decreased brain zinc availability reduces hippocampal neurogenesis in mice and rats SW Suh, SJ Won, AM Hamby, BH Yoo, Y Fan, CT Sheline, H Tamano, ... Journal of cerebral blood flow & metabolism 29 (9), 1579-1588, 2009 | 154 | 2009 |
L-type Ca2+ channel-mediated Zn2+ toxicity and modulation by ZnT-1 in PC12 cells AH Kim, CT Sheline, M Tian, T Higashi, RJ McMahon, RJ Cousins, ... Brain research 886 (1-2), 99-107, 2000 | 134 | 2000 |
Zinc-induced neuronal death in cortical neurons. D Lobner, LM Canzoniero, P Manzerra, F Gottron, H Ying, M Knudson, ... Cellular and molecular biology (Noisy-le-Grand, France) 46 (4), 797-806, 2000 | 122 | 2000 |
Trans-activation by human immunodeficiency virus Tat protein requires the C-terminal domain of RNA polymerase II. H Okamoto, CT Sheline, JL Corden, KA Jones, BM Peterlin Proceedings of the National Academy of Sciences 93 (21), 11575-11579, 1996 | 119 | 1996 |
Cu2+ toxicity inhibition of mitochondrial dehydrogenases in vitro and in vivo CT Sheline, DW Choi Annals of Neurology: Official Journal of the American Neurological …, 2004 | 117 | 2004 |
Sequential release of nitric oxide, zinc, and superoxide in hypoglycemic neuronal death SW Suh, AM Hamby, ET Gum, BS Shin, SJ Won, CT Sheline, PH Chan, ... Journal of Cerebral Blood Flow & Metabolism 28 (10), 1697-1706, 2008 | 105 | 2008 |
Zip4 (Slc39a4) expression is activated in hepatocellular carcinomas and functions to repress apoptosis, enhance cell cycle and increase migration BP Weaver, Y Zhang, S Hiscox, GL Guo, U Apte, KM Taylor, CT Sheline, ... PloS one 5 (10), e13158, 2010 | 102 | 2010 |
Sublethal oxygen–glucose deprivation alters hippocampal neuronal AMPA receptor expression and vulnerability to kainate-induced death HS Ying, JH Weishaupt, M Grabb, LMT Canzoniero, SL Sensi, CT Sheline, ... Journal of Neuroscience 17 (24), 9536-9544, 1997 | 87 | 1997 |
Zinc neurotoxicity is dependent on intracellular NAD+ levels and the sirtuin pathway AL Cai, GJ Zipfel, CT Sheline European Journal of Neuroscience 24 (8), 2169-2176, 2006 | 86 | 2006 |
Free radical-mediated neurotoxicity may be caused by inhibition of mitochondrial dehydrogenases in vitro and in vivo CT Sheline, L Wei Neuroscience 140 (1), 235-246, 2006 | 72 | 2006 |
Cofactors of mitochondrial enzymes attenuate copper‐induced death in vitro and in vivo CT Sheline, EH Choi, JS Kim‐Han, LL Dugan, DW Choi Annals of neurology 52 (2), 195-204, 2002 | 67 | 2002 |
Neuronal death in cultured murine cortical cells is induced by inhibition of GAPDH and triosephosphate isomerase CT Sheline, DW Choi Neurobiology of disease 5 (1), 47-54, 1998 | 64 | 1998 |
Membrane-permeant chelators can attenuate Zn2+-induced cortical neuronal death LMT Canzoniero, P Manzerra, CT Sheline, DW Choi Neuropharmacology 45 (3), 420-428, 2003 | 53 | 2003 |
Mitochondrial inhibitor models of Huntington’s disease and Parkinson’s disease induce zinc accumulation and are attenuated by inhibition of zinc neurotoxicity in vitro or in vivo CT Sheline, J Zhu, W Zhang, C Shi, AL Cai Neurodegenerative Diseases 11 (1), 49-58, 2012 | 51 | 2012 |
Depolarization-induced 65zinc influx into cultured cortical neurons CT Sheline, HS Ying, CS Ling, LMT Canzoniero, DW Choi Neurobiology of disease 10 (1), 41-53, 2002 | 48 | 2002 |