Dhruv Sethi, Ph.D.
Dhruv Sethi, Ph.D.
Dana-Farber Cancer Instt, Harvard Medical School
Verified email at dfci.harvard.edu
Title
Cited by
Cited by
Year
Deconstructing the peptide-MHC specificity of T cell recognition
ME Birnbaum, JL Mendoza, DK Sethi, S Dong, J Glanville, J Dobbins, ...
Cell 157 (5), 1073-1087, 2014
3422014
Crystal structure of the HLA-DM–HLA-DR1 complex defines mechanisms for rapid peptide selection
W Pos, DK Sethi, MJ Call, MSED Schulze, AK Anders, J Pyrdol, ...
Cell 151 (7), 1557-1568, 2012
1322012
Differential epitope positioning within the germline antibody paratope enhances promiscuity in the primary immune response
DK Sethi, A Agarwal, V Manivel, KVS Rao, DM Salunke
Immunity 24 (4), 429-438, 2006
1152006
A highly tilted binding mode by a self-reactive T cell receptor results in altered engagement of peptide and MHC
DK Sethi, DA Schubert, AK Anders, A Heroux, DA Bonsor, CP Thomas, ...
Journal of Experimental Medicine 208 (1), 91-102, 2011
882011
Self-reactive human CD4 T cell clones form unusual immunological synapses
DA Schubert, S Gordo, JJ Sabatino, S Vardhana, E Gagnon, DK Sethi, ...
The Journal of experimental medicine 209 (2), 335-352, 2012
672012
T cell receptor recognition of self and foreign antigens in the induction of autoimmunity
KW Wucherpfennig, D Sethi
Seminars in immunology 23 (2), 84-91, 2011
652011
Mechanisms of peptide repertoire selection by HLA-DM
W Pos, DK Sethi, KW Wucherpfennig
Trends in immunology 34 (10), 495-501, 2013
442013
Crystal Structures of the PNA− Porphyrin Complex in the Presence and Absence of Lactose: Mapping the Conformational Changes on Lactose Binding, Interacting Surfaces, and …
M Goel, RS Damai, DK Sethi, KJ Kaur, BG Maiya, MJ Swamy, ...
Biochemistry 44 (15), 5588-5596, 2005
312005
Crossreactivity of a human autoimmune TCR is dominated by a single TCR loop
DK Sethi, S Gordo, DA Schubert, KW Wucherpfennig
Nature communications 4 (1), 1-10, 2013
292013
Identification and characterization of EhCaBP2 a second member of the calcium-binding protein family of the protozoan parasite Entamoeba histolytica
P Chakrabarty, DK Sethi, N Padhan, KJ Kaur, DM Salunke, ...
Journal of Biological Chemistry 279 (13), 12898-12908, 2004
232004
Cell surface display of functional human MHC class II proteins: yeast display versus insect cell display
F Wen, DK Sethi, KW Wucherpfennig, H Zhao
Protein Engineering, Design & Selection 24 (9), 701-709, 2011
192011
Purification, identification and preliminary crystallographic studies of Pru du amandin, an allergenic protein from Prunus dulcis
V Gaur, DK Sethi, DM Salunke
Acta Crystallographica Section F: Structural Biology and Crystallization …, 2008
162008
Disruption of hydrogen bonds between major histocompatibility complex class II and the peptide N-terminus is not sufficient to form a human leukocyte antigen-DM receptive state …
MSED Schulze, AK Anders, DK Sethi, MJ Call
PLoS One 8 (7), e69228, 2013
152013
Purification, identification and preliminary crystallographic studies of an allergenic protein from Lathyrus sativus
IA Qureshi, DK Sethi, DM Salunke
Acta Crystallographica Section F: Structural Biology and Crystallization …, 2006
152006
Abstract LB-013: CAR-Ts armored with small molecule-regulated IL12 or CD40L cassettes for enhanced activity against solid tumors
M Ols, M Schebesta, E Brideau, K Elpek, M Fleury, J Gori, S Heller, DJ Li, ...
Cancer Research 79 (13 Supplement), LB-013-LB-013, 2019
12019
Drug responsive domain regulation of IL15-engineered T cells provides pharmacological control over antigen-independent cell expansion
S Shamah, K Elpek, T Ezell, M Fleury, M Gallo, J Gori, S Heller, M Inniss, ...
Cancer Research 80 (16 Supplement), 6604-6604, 2020
2020
Regulated Membrane-Bound IL15 Drives Controlled Expansion of Tumor Reactive Lymphocytes
KG Elpek, T Ezell, M Fleury, M Langley, K Tran, M Gallo, DK Sethi, D Sun, ...
MOLECULAR THERAPY 28 (4), 332-332, 2020
2020
Regulation of CD40L Transgene Expression in Human CAR-T Cells Using FDA Approved Ligands
E Weisman, E Brideau, K Elpek, M Fleury, S Heller, C Reardon, ...
MOLECULAR THERAPY 27 (4), 266-266, 2019
2019
Structure and Function of TCRαβ Receptors
KW Wucherpfennig, DK Sethi
Academic Press, 2016
2016
Structural Characterization of an Unusual Binding Mode of a Myelin-specific T Cell Receptor
D Sethi, D Schubert, K Wilbuer, K Wucherpfennig
Clinical Immunology, S71, 2010
2010
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Articles 1–20