Promoting basal levels of autophagy in the nervous system enhances longevity and oxidant resistance in adult Drosophila A Simonsen, RC Cumming, A Brech, P Isakson, DR Schubert, KD Finley Autophagy 4 (2), 176-184, 2008 | 795 | 2008 |
Protein disulfide bond formation in the cytoplasm during oxidative stress RC Cumming, NL Andon, PA Haynes, M Park, WH Fischer, D Schubert Journal of biological chemistry 279 (21), 21749-21758, 2004 | 571 | 2004 |
The regulation of glucose metabolism by HIF-1 mediates a neuroprotective response to amyloid beta peptide T Soucek, R Cumming, R Dargusch, P Maher, D Schubert Neuron 39 (1), 43-56, 2003 | 304 | 2003 |
Fanconi anemia group C protein prevents apoptosis in hematopoietic cells through redox regulation of GSTP1 RC Cumming, J Lightfoot, K Beard, H Youssoufian, PJ O'Brien, ... Nature medicine 7 (7), 814-820, 2001 | 293 | 2001 |
Analysis of gene expression in a complex differentiation hierarchy by global amplification of cDNA from single cells G Brady, F Billia, J Knox, T Hoang, IR Kirsch, EB Voura, RG Hawley, ... Current Biology 5 (8), 909-922, 1995 | 232 | 1995 |
p62, Ref (2) P and ubiquitinated proteins are conserved markers of neuronal aging, aggregate formation and progressive autophagic defects BJ Bartlett, P Isakson, J Lewerenz, H Sanchez, RW Kotzebue, ... Autophagy 7 (6), 572-583, 2011 | 218 | 2011 |
Amyloid‐β induces disulfide bonding and aggregation of GAPDH in Alzheimer's disease RC Cumming, D Schubert The FASEB journal 19 (14), 2060-2062, 2005 | 156 | 2005 |
Amyloid beta resistance in nerve cell lines is mediated by the Warburg effect JT Newington, A Pitts, A Chien, R Arseneault, D Schubert, RC Cumming PloS one 6 (4), e19191, 2011 | 120 | 2011 |
Reevaluating metabolism in Alzheimer's disease from the perspective of the astrocyte-neuron lactate shuttle model JT Newington, RA Harris, RC Cumming Journal of neurodegenerative diseases 2013, 2013 | 119 | 2013 |
Overexpression of pyruvate dehydrogenase kinase 1 and lactate dehydrogenase A in nerve cells confers resistance to amyloid β and other toxins by decreasing mitochondrial … JT Newington, T Rappon, S Albers, DY Wong, RJ Rylett, RC Cumming Journal of Biological Chemistry 287 (44), 37245-37258, 2012 | 116 | 2012 |
Suppression of apoptosis in hematopoietic factor-dependent progenitor cell lines by expression of the FAC gene RC Cumming, JM Liu, H Youssoufian, M Buchwald | 102 | 1996 |
Blue cheese mutations define a novel, conserved gene involved in progressive neural degeneration KD Finley, PT Edeen, RC Cumming, MD Mardahl-Dumesnil, BJ Taylor, ... Journal of Neuroscience 23 (4), 1254-1264, 2003 | 94 | 2003 |
Aerobic glycolysis in the frontal cortex correlates with memory performance in wild-type mice but not the APP/PS1 mouse model of cerebral amyloidosis RA Harris, L Tindale, A Lone, O Singh, SL Macauley, M Stanley, ... Journal of Neuroscience 36 (6), 1871-1878, 2016 | 91 | 2016 |
Attenuation of LDHA expression in cancer cells leads to redox-dependent alterations in cytoskeletal structure and cell migration R Arseneault, A Chien, JT Newington, T Rappon, R Harris, RC Cumming Cancer letters 338 (2), 255-266, 2013 | 91 | 2013 |
Genetic Modifiers of the Drosophila Blue Cheese Gene Link Defects in Lysosomal Transport With Decreased Life Span and Altered Ubiquitinated-Protein Profiles A Simonsen, RC Cumming, K Lindmo, V Galaviz, S Cheng, TE Rusten, ... Genetics 176 (2), 1283-1297, 2007 | 88 | 2007 |
Age-dependent metabolic dysregulation in cancer and Alzheimer’s disease RA Harris, L Tindale, RC Cumming Biogerontology 15, 559-577, 2014 | 78 | 2014 |
Increase in expression levels and resistance to sulfhydryl oxidation of peroxiredoxin isoforms in amyloid β-resistant nerve cells RC Cumming, R Dargusch, WH Fischer, D Schubert Journal of biological chemistry 282 (42), 30523-30534, 2007 | 69 | 2007 |
Lactate preconditioning promotes a HIF-1α-mediated metabolic shift from OXPHOS to glycolysis in normal human diploid fibroblasts AM Kozlov, A Lone, DH Betts, RC Cumming Scientific reports 10 (1), 8388, 2020 | 53 | 2020 |
Aerobic glycolysis is required for spatial memory acquisition but not memory retrieval in mice RA Harris, A Lone, H Lim, F Martinez, AK Frame, TJ Scholl, RC Cumming Eneuro 6 (1), 2019 | 51 | 2019 |
High temperature tolerance and thermal plasticity in emerald ash borer Agrilus planipennis S Sobek, A Rajamohan, D Dillon, RC Cumming, BJ Sinclair Agricultural and Forest Entomology 13 (3), 333-340, 2011 | 46 | 2011 |