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Mads Kjolby
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Camostat mesylate inhibits SARS-CoV-2 activation by TMPRSS2-related proteases and its metabolite GBPA exerts antiviral activity
M Hoffmann, H Hofmann-Winkler, JC Smith, N Krüger, P Arora, ...
EBioMedicine 65, 2021
3072021
Sort1, encoded by the cardiovascular risk locus 1p13. 3, is a regulator of hepatic lipoprotein export
M Kjolby, OM Andersen, T Breiderhoff, AW Fjorback, KM Pedersen, ...
Cell metabolism 12 (3), 213-223, 2010
2982010
IFI16 is required for DNA sensing in human macrophages by promoting production and function of cGAMP
KL Jønsson, A Laustsen, C Krapp, KA Skipper, K Thavachelvam, D Hotter, ...
Nature communications 8 (1), 14391, 2017
2832017
Sortilin mediates vascular calcification via its recruitment into extracellular vesicles
C Goettsch, JD Hutcheson, M Aikawa, H Iwata, T Pham, A Nykjaer, ...
The Journal of clinical investigation 126 (4), 1323-1336, 2016
2302016
Sortilin associates with Trk receptors to enhance anterograde transport and neurotrophin signaling
CB Vaegter, P Jansen, AW Fjorback, S Glerup, S Skeldal, M Kjolby, ...
Nature neuroscience 14 (1), 54-61, 2011
2122011
The hypercholesterolemia-risk gene SORT1 facilitates PCSK9 secretion
C Gustafsen, M Kjolby, M Nyegaard, M Mattheisen, J Lundhede, ...
Cell metabolism 19 (2), 310-318, 2014
1882014
Efficacy of the TMPRSS2 inhibitor camostat mesilate in patients hospitalized with Covid-19-a double-blind randomized controlled trial.
JD Gunst, NB Staerke, MH Pahus, LH Kristensen, J Bodilsen, N Lohse, ...
EClinicalMedicine 35, 2021
1642021
Targeting sortilin in immune cells reduces proinflammatory cytokines and atherosclerosis
MB Mortensen, M Kjolby, S Gunnersen, JV Larsen, J Palmfeldt, E Falk, ...
The Journal of clinical investigation 124 (12), 5317-5322, 2014
1392014
Diverse cellular architecture of atherosclerotic plaque derives from clonal expansion of a few medial SMCs
K Jacobsen, MB Lund, J Shim, S Gunnersen, EM Füchtbauer, M Kjolby, ...
JCI insight 2 (19), 2017
1362017
Camostat mesylate against SARS‐CoV‐2 and COVID‐19—Rationale, dosing and safety
P Breining, AL Frølund, JF Højen, JD Gunst, NB Staerke, E Saedder, ...
Basic & clinical pharmacology & toxicology 128 (2), 204-212, 2021
1322021
A single injection of gain-of-function mutant PCSK9 adeno-associated virus vector induces cardiovascular calcification in mice with no genetic modification
C Goettsch, JD Hutcheson, S Hagita, MA Rogers, MD Creager, T Pham, ...
Atherosclerosis 251, 109-118, 2016
1232016
Potential genetic modifiers of disease risk and age at onset in patients with frontotemporal lobar degeneration and GRN mutations: a genome-wide association study
C Pottier, X Zhou, RB Perkerson, M Baker, GD Jenkins, DJ Serie, ...
The Lancet Neurology 17 (6), 548-558, 2018
1132018
Sortilin and its multiple roles in cardiovascular and metabolic diseases
C Goettsch, M Kjolby, E Aikawa
Arteriosclerosis, thrombosis, and vascular biology 38 (1), 19-25, 2018
1052018
Plasma clearance of hemoglobin and haptoglobin in mice and effect of CD163 gene targeting disruption
A Etzerodt, M Kjolby, MJ Nielsen, M Maniecki, P Svendsen, SK Moestrup
Antioxidants & redox signaling 18 (17), 2254-2263, 2013
962013
SorCS2 regulates dopaminergic wiring and is processed into an apoptotic two-chain receptor in peripheral glia
S Glerup, D Olsen, CB Vaegter, C Gustafsen, SS Sjoegaard, G Hermey, ...
Neuron 82 (5), 1074-1087, 2014
932014
SorCS2 is required for BDNF-dependent plasticity in the hippocampus
S Glerup, U Bolcho, S Mølgaard, S Bøggild, CB Vaegter, AH Smith, ...
Molecular psychiatry 21 (12), 1740-1751, 2016
882016
Sortilin, encoded by the cardiovascular risk gene SORT1, and its suggested functions in cardiovascular disease
M Kjolby, MS Nielsen, CM Petersen
Current atherosclerosis reports 17, 1-9, 2015
872015
Volume natriuresis vs. pressure natriuresis
P Bie, S Wamberg, M Kjolby
Acta physiologica scandinavica 181 (4), 495-503, 2004
712004
SorLA controls neurotrophic activity by sorting of GDNF and its receptors GFRα1 and RET
S Glerup, M Lume, D Olsen, JR Nyengaard, CB Vaegter, C Gustafsen, ...
Cell reports 3 (1), 186-199, 2013
702013
Sortilins: new players in lipoprotein metabolism
TE Willnow, M Kjølby, A Nykjaer
Current opinion in lipidology 22 (2), 79-85, 2011
562011
Il sistema al momento non può eseguire l'operazione. Riprova più tardi.
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