piter bosma
piter bosma
associate professor of Gene Therapy, Tytgat Institute, AMC,Amsterdam
Email verificata su amc.uva.nl
Titolo
Citata da
Citata da
Anno
The genetic basis of the reduced expression of bilirubin UDP-glucuronosyltransferase 1 in Gilbert's syndrome
PJ Bosma, JR Chowdhury, C Bakker, S Gantla, A De Boer, BA Oostra, ...
New England Journal of Medicine 333 (18), 1171-1175, 1995
15951995
Ischemia/reperfusion injury and cardioprotective mechanisms: role of mitochondria and reactive oxygen species
MG Perrelli, P Pagliaro, C Penna
World journal of cardiology 3 (6), 186, 2011
997*2011
Congenital jaundice in rats with a mutation in a multidrug resistance-associated protein gene
CC Paulusma, PJ Bosma, GJR Zaman, CTM Bakker, M Otter, GL Scheffer, ...
Science 271 (5252), 1126-1128, 1996
9481996
Mutations in the MDR3 gene cause progressive familial intrahepatic cholestasis
JML De Vree, E Jacquemin, E Sturm, D Cresteil, PJ Bosma, J Aten, ...
Proceedings of the National Academy of Sciences 95 (1), 282-287, 1998
7761998
A mutation in the human canalicular multispecific organic anion transporter gene causes the Dubin‐Johnson syndrome
CC Paulusma, M Kool, PJ Bosma, GL Scheffer, F ter Borg, RJ Scheper, ...
Hepatology 25 (6), 1539-1542, 1997
6191997
The wide spectrum of multidrug resistance 3 deficiency: from neonatal cholestasis to cirrhosis of adulthood
E Jacquemin, O Bernard, M Hadchouel, D Cresteil, JML De Vree, M Paul, ...
Gastroenterology 120 (6), 1448-1458, 2001
4852001
Bilirubin UDP-glucuronosyltransferase 1 is the only relevant bilirubin glucuronidating isoform in man.
PJ Bosma, J Seppen, B Goldhoorn, C Bakker, RPO Elferink, ...
Journal of Biological Chemistry 269 (27), 17960-17964, 1994
4561994
Inherited disorders of bilirubin metabolism
PJ Bosma
Journal of hepatology 38 (1), 107-117, 2003
3122003
Prognostic significance of elevated cyclooxygenase 2 expression in patients with adenocarcinoma of the esophagus
CJ Buskens, BP Van Rees, A Sivula, JB Reitsma, C Haglund, PJ Bosma, ...
Gastroenterology 122 (7), 1800-1807, 2002
3102002
Plasminogen activator inhibitor 1: biosynthesis and mRNA level are increased by insulin in cultured human hepatocytes
T Kooistra, PJ Bosma, HAM Tns, AP Van den Berg, P Meyer, ...
Thrombosis and haemostasis 61 (02), 723-728, 1989
2341989
Sequence of exons and the flanking regions of human bilirubin‐UDP‐glucuronosyltransferase gene complex and identification of a genetic mutation in a patient with Crigler‐Najjar…
PJ Bosma, NR Chowdhury, BG Goldhoorn, MH Hofker, RPJO Elferink, ...
Hepatology 15 (5), 941-947, 1992
2111992
Correction of liver disease by hepatocyte transplantation in a mouse model of progressive familial intrahepatic cholestasis
JML De Vree, R Ottenhoff, PJ Bosma, AJ Smith, J Aten, RPJO Elferink
Gastroenterology 119 (6), 1720-1730, 2000
2022000
Human plasminogen activator inhibitor-1 gene. Promoter and structural gene nucleotide sequences.
PJ Bosma, EA Van den Berg, T Kooistra, DR Siemieniak, JL Slightom
Journal of Biological Chemistry 263 (19), 9129-9141, 1988
1911988
Discrimination between Crigler-Najjar type I and II by expression of mutant bilirubin uridine diphosphate-glucuronosyltransferase.
J Seppen, PJ Bosma, BG Goldhoorn, CT Bakker, JR Chowdhury, ...
The Journal of clinical investigation 94 (6), 2385-2391, 1994
1721994
Zonal down‐regulation and redistribution of the multidrug resistance protein 2 during bile duct ligation in rat liver
CC Paulusma, MJ Kothe, CT Bakker, PJ Bosma, I van Bokhoven, ...
Hepatology 31 (3), 684-693, 2000
1502000
Transcriptional profiling reveals novel markers of liver fibrogenesis gremlin and insulin-like growth factor-binding proteins
W Boers, S Aarrass, C Linthorst, M Pinzani, RO Elferink, P Bosma
Journal of Biological Chemistry 281 (24), 16289-16295, 2006
1452006
Improved gene transfer efficiency to primary and established human pancreatic carcinoma target cells via epidermal growth factor receptor and integrin-targeted adenoviral vectors
JG Wesseling, PJ Bosma, V Krasnykh, EA Kashentseva, JL Blackwell, ...
Gene therapy 8 (13), 969-976, 2001
1372001
Mechanisms of inherited deficiencies of multiple UDP‐glucuronosyltransferase isoforms in two patients with Crigler‐Najjar syndrome, type I
PJ Bosma, JR Chowdhury, TJ Huang, P Lahiri, RPJO Elferink, ...
The FASEB journal 6 (10), 2859-2863, 1992
1231992
A mutation in bilirubin uridine 5′-diphosphate-glucuronosyltransferase isoform 1 causing Crigler-Najjar syndrome type II
PJ Bosma, B Goldhoorn, RPJO Elferink, M Sinaasappel, BA Oostra, ...
Gastroenterology 105 (1), 216-220, 1993
1211993
Towards liver-directed gene therapy for Crigler-Najjar syndrome
PS Montenegro Miranda, PJ Bosma
Current gene therapy 9 (2), 72-82, 2009
892009
Il sistema al momento non pu eseguire l'operazione. Riprova pi tardi.
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