|Synthetic amyloid-β oligomers impair long-term memory independently of cellular prion protein|
C Balducci, M Beeg, M Stravalaci, A Bastone, A Sclip, E Biasini, L Tapella, ...
Proceedings of the National Academy of Sciences 107 (5), 2295-2300, 2010
|Mutant PrP is delayed in its exit from the endoplasmic reticulum, but neither wild-type nor mutant PrP undergoes retrotranslocation prior to proteasomal degradation|
B Drisaldi, RS Stewart, C Adles, LR Stewart, E Quaglio, E Biasini, L Fioriti, ...
Journal of Biological Chemistry 278 (24), 21732-21743, 2003
|An N-terminal fragment of the prion protein binds to amyloid-β oligomers and inhibits their neurotoxicity in vivo|
BR Fluharty, E Biasini, M Stravalaci, A Sclip, L Diomede, C Balducci, ...
Journal of Biological Chemistry 288 (11), 7857-7866, 2013
|Prion protein at the crossroads of physiology and disease|
E Biasini, JA Turnbaugh, U Unterberger, DA Harris
Trends in neurosciences 35 (2), 92-103, 2012
|Proteasome inhibition and aggregation in Parkinson's disease: a comparative study in untransfected and transfected cells|
E Biasini, L Fioriti, I Ceglia, R Invernizzi, A Bertoli, R Chiesa, G Forloni
Journal of neurochemistry 88 (3), 545-553, 2004
|Proteomic analysis of spinal cord of presymptomatic amyotrophic lateral sclerosis G93A SOD1 mouse|
T Massignan, F Casoni, M Basso, P Stefanazzi, E Biasini, M Tortarolo, ...
Biochemical and biophysical research communications 353 (3), 719-725, 2007
|Human prion proteins with pathogenic mutations share common conformational changes resulting in enhanced binding to glycosaminoglycans|
S Yin, N Pham, S Yu, C Li, P Wong, B Chang, SC Kang, E Biasini, P Tien, ...
Proceedings of the National Academy of Sciences 104 (18), 7546-7551, 2007
|An N-terminal polybasic domain and cell surface localization are required for mutant prion protein toxicity|
IH Solomon, N Khatri, E Biasini, T Massignan, JE Huettner, DA Harris
Journal of Biological Chemistry 286 (16), 14724-14736, 2011
|Aggregated, wild-type prion protein causes neurological dysfunction and synaptic abnormalities|
R Chiesa, P Piccardo, E Biasini, B Ghetti, DA Harris
Journal of Neuroscience 28 (49), 13258-13267, 2008
|The N-terminal, polybasic region of PrPC dictates the efficiency of prion propagation by binding to PrPSc|
JA Turnbaugh, U Unterberger, P SaŠ, T Massignan, BR Fluharty, ...
Journal of Neuroscience 32 (26), 8817-8830, 2012
|Non‐infectious aggregates of the prion protein react with several PrPSc‐directed antibodies|
E Biasini, ME Seegulam, BN Patti, L Solforosi, AZ Medrano, ...
Journal of neurochemistry 105 (6), 2190-2204, 2008
|Redox regulation of cyclophilin A by glutathionylation|
P Ghezzi, S Casagrande, T Massignan, M Basso, E Bellacchio, L Mollica, ...
Proteomics 6 (3), 817-825, 2006
|The N-terminal, polybasic region is critical for prion protein neuroprotective activity|
JA Turnbaugh, L Westergard, U Unterberger, E Biasini, DA Harris
PloS one 6 (9), e25675, 2011
|A mutant prion protein sensitizes neurons to glutamate-induced excitotoxicity|
E Biasini, U Unterberger, IH Solomon, T Massignan, A Senatore, H Bian, ...
Journal of Neuroscience 33 (6), 2408-2418, 2013
|A novel, drug-based, cellular assay for the activity of neurotoxic mutants of the prion protein|
T Massignan, RS Stewart, E Biasini, IH Solomon, V Bonetto, R Chiesa, ...
Journal of Biological Chemistry 285 (10), 7752-7765, 2010
|Multiple biochemical similarities between infectious and non‐infectious aggregates of a prion protein carrying an octapeptide insertion|
E Biasini, AZ Medrano, S Thellung, R Chiesa, DA Harris
Journal of neurochemistry 104 (5), 1293-1308, 2008
|GFP-tagged mutant prion protein forms intra-axonal aggregates in transgenic mice|
AZ Medrano, SJ Barmada, E Biasini, DA Harris
Neurobiology of disease 31 (1), 20-32, 2008
|Ion channels induced by the prion protein: mediators of neurotoxicity|
IH Solomon, E Biasini, DA Harris
Prion 6 (1), 40-45, 2012
|Mutant prion protein expression is associated with an alteration of the Rab GDP dissociation inhibitor α (GDI)/Rab11 pathway|
T Massignan, E Biasini, E Lauranzano, P Veglianese, M Pignataro, ...
Molecular & Cellular Proteomics 9 (4), 611-622, 2010
|Role of lipid rafts and GM1 in the segregation and processing of prion protein|
L Botto, D Cunati, S Coco, S Sesana, A Bulbarelli, E Biasini, L Colombo, ...
PLoS One 9 (5), e98344, 2014