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Morgan Simpson
Morgan Simpson
Email verificata su virginia.edu
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Colitis-induced Th17 cells increase the risk for severe subsequent Clostridium difficile infection
MM Saleh, AL Frisbee, JL Leslie, EL Buonomo, CA Cowardin, JZ Ma, ...
Cell host & microbe 25 (5), 756-765. e5, 2019
1222019
IL-33 drives group 2 innate lymphoid cell-mediated protection during Clostridium difficile infection
AL Frisbee, MM Saleh, MK Young, JL Leslie, ME Simpson, ...
Nature communications 10 (1), 1-13, 2019
1062019
Gut microbiome communication with bone marrow regulates susceptibility to amebiasis
SL Burgess, JL Leslie, MJ Uddin, DN Oakland, CA Gilchrist, GB Moreau, ...
The Journal of Clinical Investigation, 2020
392020
Biological studies and target engagement of the 2-C-methyl-d-erythritol 4-phosphate cytidylyltransferase (IspD)-targeting antimalarial agent (1 R, 3 S)-MMV008138 and analogs
M Ghavami, EF Merino, ZK Yao, R Elahi, ME Simpson, ...
ACS infectious diseases 4 (4), 549-559, 2017
392017
Determination of the active stereoisomer of the MEP pathway-targeting antimalarial agent MMV008138, and initial structure–activity studies
ZK Yao, PM Krai, EF Merino, ME Simpson, C Slebodnick, MB Cassera, ...
Bioorganic & medicinal chemistry letters 25 (7), 1515-1519, 2015
322015
TLR2 as a Therapeutic Target in Bacterial Infection
ME Simpson, WA Petri Jr
Trends in molecular medicine, 2020
312020
Structure-activity studies of IspD-targeting antimalarials related to MMV008138
ZK Yao, M Ghavami, R Elahi, M Simpson, E Merino, M Totrov, M Cassera, ...
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 252, 2016
2016
HIT TO LEAD OPTIMIZATION OF THE APICOPLAST-TARGETING ANTIMALARIAL AGENT MMV008138
ZK Yao, PM Krai, EF Merino, ME Simpson, C Slebodnick, MB Cassera, ...
AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE 93 (4), 77-77, 2015
2015
Il sistema al momento non può eseguire l'operazione. Riprova più tardi.
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