Colitis-induced Th17 cells increase the risk for severe subsequent Clostridium difficile infection MM Saleh, AL Frisbee, JL Leslie, EL Buonomo, CA Cowardin, JZ Ma, ... Cell host & microbe 25 (5), 756-765. e5, 2019 | 122 | 2019 |
IL-33 drives group 2 innate lymphoid cell-mediated protection during Clostridium difficile infection AL Frisbee, MM Saleh, MK Young, JL Leslie, ME Simpson, ... Nature communications 10 (1), 1-13, 2019 | 106 | 2019 |
Gut microbiome communication with bone marrow regulates susceptibility to amebiasis SL Burgess, JL Leslie, MJ Uddin, DN Oakland, CA Gilchrist, GB Moreau, ... The Journal of Clinical Investigation, 2020 | 39 | 2020 |
Biological studies and target engagement of the 2-C-methyl-d-erythritol 4-phosphate cytidylyltransferase (IspD)-targeting antimalarial agent (1 R, 3 S)-MMV008138 and analogs M Ghavami, EF Merino, ZK Yao, R Elahi, ME Simpson, ... ACS infectious diseases 4 (4), 549-559, 2017 | 39 | 2017 |
Determination of the active stereoisomer of the MEP pathway-targeting antimalarial agent MMV008138, and initial structure–activity studies ZK Yao, PM Krai, EF Merino, ME Simpson, C Slebodnick, MB Cassera, ... Bioorganic & medicinal chemistry letters 25 (7), 1515-1519, 2015 | 32 | 2015 |
TLR2 as a Therapeutic Target in Bacterial Infection ME Simpson, WA Petri Jr Trends in molecular medicine, 2020 | 31 | 2020 |
Structure-activity studies of IspD-targeting antimalarials related to MMV008138 ZK Yao, M Ghavami, R Elahi, M Simpson, E Merino, M Totrov, M Cassera, ... ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 252, 2016 | | 2016 |
HIT TO LEAD OPTIMIZATION OF THE APICOPLAST-TARGETING ANTIMALARIAL AGENT MMV008138 ZK Yao, PM Krai, EF Merino, ME Simpson, C Slebodnick, MB Cassera, ... AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE 93 (4), 77-77, 2015 | | 2015 |