Dmitri Kireev
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A chemical probe selectively inhibits G9a and GLP methyltransferase activity in cells
M Vedadi, D Barsyte-Lovejoy, F Liu, S Rival-Gervier, A Allali-Hassani, ...
Nat Chem Biol 7 (8), 566-574, 2011
Discovery of a 2, 4-diamino-7-aminoalkoxyquinazoline as a potent and selective inhibitor of histone lysine methyltransferase G9a
F Liu, X Chen, A Allali-Hassani, AM Quinn, GA Wasney, A Dong, ...
Journal of medicinal chemistry 52 (24), 7950-7953, 2009
Protein lysine methyltransferase G9a inhibitors: design, synthesis, and structure activity relationships of 2, 4-diamino-7-aminoalkoxy-quinazolines.
F Liu, X Chen, A Allali-Hassani, AM Quinn, TJ Wigle, GA Wasney, A Dong, ...
Journal of medicinal chemistry 53 (15), 5844-5857, 2010
Discovery of a chemical probe for the L3MBTL3 methyllysine reader domain
LI James, D Barsyte-Lovejoy, N Zhong, L Krichevsky, VK Korboukh, ...
Nature chemical biology 9 (3), 184-191, 2013
Multivalent histone engagement by the linked tandem Tudor and PHD domains of UHRF1 is required for the epigenetic inheritance of DNA methylation
SB Rothbart, BM Dickson, MS Ong, K Krajewski, S Houliston, DB Kireev, ...
Genes & development 27 (11), 1288-1298, 2013
Complete Thermodynamic Description of H‐Bonding in the Framework of Multiplicative Approach
OA Raevsky, VY Grigor'ev, DB Kireev, NS Zefirov
Quantitative Structure‐Activity Relationships 11 (1), 49-63, 1992
Small-molecule ligands of methyl-lysine binding proteins
JM Herold, TJ Wigle, JL Norris, R Lam, VK Korboukh, C Gao, ...
Journal of medicinal chemistry 54 (7), 2504-2511, 2011
UNC2025, a Potent and Orally Bioavailable MER/FLT3 Dual Inhibitor
W Zhang, D DeRyckere, D Hunter, J Liu, MA Stashko, KA Minson, ...
Journal of medicinal chemistry 57 (16), 7031-7041, 2014
Discovery of small molecule mer kinase inhibitors for the treatment of pediatric acute lymphoblastic leukemia
J Liu, C Yang, C Simpson, D DeRyckere, A Van Deusen, MJ Miley, ...
ACS medicinal chemistry letters 3 (2), 129-134, 2012
Structural protein–ligand interaction fingerprints (SPLIF) for structure-based virtual screening: method and benchmark study
C Da, D Kireev
Journal of chemical information and modeling 54 (9), 2555-2561, 2014
Screening for Inhibitors of Low-Affinity Epigenetic Peptide-Protein Interactions: An AlphaScreen™-Based Assay for Antagonists of Methyl-Lysine Binding Proteins
TJ Wigle, J Martin Herold, GA Senisterra, M Vedadi, DB Kireev, ...
Journal of biomolecular screening 15 (1), 62-71, 2010
A 3D QSAR study of a series of HEPT analogues: the influence of conformational mobility on HIV-1 reverse transcriptase inhibition
DB Kireev, JR Chrétien, DS Grierson, C Monneret
Journal of medicinal chemistry 40 (26), 4257-4264, 1997
UNC1062, a new and potent Mer inhibitor
J Liu, W Zhang, MA Stashko, D DeRyckere, CT Cummings, D Hunter, ...
European journal of medicinal chemistry 65, 83-93, 2013
Small-molecule ligands of methyl-lysine binding proteins: optimization of selectivity for L3MBTL3
LI James, VK Korboukh, L Krichevsky, BM Baughman, JM Herold, ...
Journal of medicinal chemistry 56 (18), 7358-7371, 2013
Pseudo-cyclization through intramolecular hydrogen bond enables discovery of pyridine substituted pyrimidines as new Mer kinase inhibitors
W Zhang, D Zhang, MA Stashko, D DeRyckere, D Hunter, D Kireev, ...
Journal of medicinal chemistry 56 (23), 9683-9692, 2013
UNC569, a novel small-molecule mer inhibitor with efficacy against acute lymphoblastic leukemia in vitro and in vivo
S Christoph, D DeRyckere, J Schlegel, JK Frazer, LA Batchelor, ...
Molecular cancer therapeutics 12 (11), 2367-2377, 2013
Identification of non-peptide malignant brain tumor (MBT) repeat antagonists by virtual screening of commercially available compounds
D Kireev, TJ Wigle, J Norris-Drouin, JM Herold, WP Janzen, SV Frye
Journal of medicinal chemistry 53 (21), 7625-7631, 2010
Discovery of Mer specific tyrosine kinase inhibitors for the treatment and prevention of thrombosis
W Zhang, AL McIver, MA Stashko, D DeRyckere, BR Branchford, D Hunter, ...
Journal of medicinal chemistry 56 (23), 9693-9700, 2013
Automated docking of 82 N-benzylpiperidine derivatives to mouse acetylcholinesterase and comparative molecular field analysis with 'natural' alignment
P Bernard, DB Kireev, JR Chrétien, PL Fortier, L Coppet
Journal of Computer-Aided Molecular Design 13, 355-371, 1999
High-throughput screening for RecA inhibitors using a transcreener adenosine 5′-O-diphosphate assay
EJR Peterson, WP Janzen, D Kireev, SF Singleton
Assay and drug development technologies 10 (3), 260-268, 2012
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