| PGH synthase and lipoxygenase generate superoxide in the presence of NADH or NADPH. RC Kukreja, HA Kontos, ML Hess, EF Ellis Circulation research 59 (6), 612-619, 1986 | 663 | 1986 |
| The oxygen free radical system: from equations through membrane-protein interactions to cardiovascular injury and protection RC Kukreja, ML Hess Cardiovascular Research 26 (7), 641-655, 1992 | 554 | 1992 |
| Phosphodiesterase-5 inhibitor sildenafil preconditions adult cardiac myocytes against necrosis and apoptosis: essential role of nitric oxide signaling A Das, L Xi, RC Kukreja Journal of Biological Chemistry 280 (13), 12944-12955, 2005 | 460 | 2005 |
| Phosphodiesterase-5 inhibition with sildenafil attenuates cardiomyocyte apoptosis and left ventricular dysfunction in a chronic model of doxorubicin cardiotoxicity PW Fisher, F Salloum, A Das, H Hyder, RC Kukreja Circulation 111 (13), 1601-1610, 2005 | 429 | 2005 |
| Anakinra, a recombinant human interleukin-1 receptor antagonist, inhibits apoptosis in experimental acute myocardial infarction A Abbate, FN Salloum, E Vecile, A Das, NN Hoke, S Straino, ... Circulation 117 (20), 2670-2683, 2008 | 422 | 2008 |
| Sildenafil (Viagra) induces powerful cardioprotective effect via opening of mitochondrial KATP channels in rabbits R Ockaili, F Salloum, J Hawkins, RC Kukreja American Journal of Physiology-Heart and Circulatory Physiology 283 (3 …, 2002 | 383 | 2002 |
| Sildenafil induces delayed preconditioning through inducible nitric oxide synthase–dependent pathway in mouse heart F Salloum, C Yin, L Xi, RC Kukreja Circulation Research 92 (6), 595-597, 2003 | 311 | 2003 |
| HIF-1 activation attenuates postischemic myocardial injury: role for heme oxygenase-1 in modulating microvascular chemokine generation R Ockaili, R Natarajan, F Salloum, BJ Fisher, D Jones, AA Fowler III, ... American Journal of Physiology-Heart and Circulatory Physiology 289 (2 …, 2005 | 293 | 2005 |
| Deoxycholic acid (DCA) causes ligand-independent activation of epidermal growth factor receptor (EGFR) and FAS receptor in primary hepatocytes: inhibition of EGFR/mitogen … L Qiao, E Studer, K Leach, R McKinstry, S Gupta, R Decker, R Kukreja, ... Molecular biology of the cell 12 (9), 2629-2645, 2001 | 271 | 2001 |
| A novel role of microRNA in late preconditioning: upregulation of endothelial nitric oxide synthase and heat shock protein 70 C Yin, FN Salloum, RC Kukreja Circulation Research 104 (5), 572-575, 2009 | 262 | 2009 |
| Pharmacological preconditioning with sildenafil: basic mechanisms and clinical implications RC Kukreja, F Salloum, A Das, R Ockaili, C Yin, YA Bremer, PW Fisher, ... Vascular pharmacology 42 (5-6), 219-232, 2005 | 261 | 2005 |
| Attenuation of dysfunction in the postischemic'stunned'myocardium by dimethylthiourea. R Bolli, WX Zhu, CJ Hartley, LH Michael, JE Repine, ML Hess, ... Circulation 76 (2), 458-468, 1987 | 246 | 1987 |
| Mitochondrial-targeted Signal transducer and activator of transcription 3 (STAT3) protects against ischemia-induced changes in the electron transport chain and the generation … K Szczepanek, Q Chen, M Derecka, FN Salloum, Q Zhang, M Szelag, ... Journal of Biological Chemistry 286 (34), 29610-29620, 2011 | 241 | 2011 |
| PDE5 inhibitors as therapeutics for heart disease, diabetes and cancer A Das, D Durrant, FN Salloum, L Xi, RC Kukreja Pharmacology & therapeutics 147, 12-21, 2015 | 235 | 2015 |
| Sildenafil (Viagra) attenuates ischemic cardiomyopathy and improves left ventricular function in mice FN Salloum, A Abbate, A Das, JE Houser, CA Mudrick, IZ Qureshi, ... American Journal of Physiology-Heart and Circulatory Physiology 294 (3 …, 2008 | 234 | 2008 |
| Hypoxia inducible factor-1 activation by prolyl 4-hydroxylase-2 gene silencing attenuates myocardial ischemia reperfusion injury R Natarajan, FN Salloum, BJ Fisher, RC Kukreja, AA Fowler III Circulation research 98 (1), 133-140, 2006 | 234 | 2006 |
| Protein kinase G-dependent cardioprotective mechanism of phosphodiesterase-5 inhibition involves phosphorylation of ERK and GSK3β∗ A Das, L Xi, RC Kukreja Journal of Biological Chemistry 283 (43), 29572-29585, 2008 | 233 | 2008 |
| Rapamycin confers preconditioning-like protection against ischemia–reperfusion injury in isolated mouse heart and cardiomyocytes SA Khan, F Salloum, A Das, L Xi, GW Vetrovec, RC Kukreja Journal of molecular and cellular cardiology 41 (2), 256-264, 2006 | 221 | 2006 |
| Opening of mitochondrial KATPchannel induces early and delayed cardioprotective effect: role of nitric oxide R Ockaili, VR Emani, S Okubo, M Brown, K Krottapalli, RC Kukreja American Journal of Physiology-Heart and Circulatory Physiology 277 (6 …, 1999 | 214 | 1999 |
| Inducible Nitric Oxide Synthase Mediates Delayed Myocardial Protection Induced by Activation of Adenosine A1 Receptors: Evidence From Gene-Knockout Mice T Zhao, L Xi, J Chelliah, JE Levasseur, RC Kukreja Circulation 102 (8), 902-907, 2000 | 213 | 2000 |
